Vioxx in high doses causes hypertension

. There are so many drugs out there," Griffin said. "I personally think that the best thing would be to get rid of the 50-milligram dose, or sell it only in packages of five.

"You hate to make people jump through hoops to get things but it should be harder to prescribe drugs that would potentially do harm."

Others who contributed to the Vanderbilt study were Patrick G. Arbogast, Ph.D., assistant professor of Preventive Medicine; James R. Daugherty, M.S., computer systems analyst in the department; and David J. Graham, M.D., of the U.S. Food and Drug Administration.

Griffin consults for Merck Research Laboratories, part of Merck & Co., Inc., which makes Vioxx, but none of the funding for this study was provided by Merck or any other pharmaceutical company.


Contact: Clinton Colmenares
Vanderbilt University Medical Center

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