HOME >> BIOLOGY >> NEWS
Viral proteins may prevent bacterial infections

KEY BISCAYNE, FL August 5, 2004 --Researchers from Rockefeller University are enlisting proteins produced by viruses in a novel strategy that may someday help prevent bacterial infections in hospitals and nursing homes.

Bacterial viruses, or bacteriophage, worm their way into bacterial cells, copy themselves and then, as an exit strategy, produce enzymes that quickly destroy the bacterial cell wall, killing the bacteria and releasing the viral offspring.

"These are highly evolved enzymes that work efficiently and rapidly to kill specific bacteria. The best use of these enzymes is to decolonize humans from carrying pathogenic bacteria in certain settings, such as hospitals, nursing homes and day care centers," says Vincent Fischetti, who is presenting data today at the American Society for Microbiology's Conference on the New Phage Biology.

Bacteria such as group A streptococci, Streptococcus pneumoniae and Staphylococcus aureus are common causes of infections, ranging from minor skin infections and ear infections in day care centers to deadly pneumonia in nursing homes and hospitals. In most instances human beings are the only reservoir of these bacteria, often carrying them unknowingly in their nose or throat. Enzymes targeting these bacteria could be delivered orally or nasally to reduce or eliminate colonization.

"If you greatly reduce the number of bacteria that are carried by individuals in these settings, the chance of infection will be minimized or even eliminated," says Fischetti.

In animal model experiments, Fischetti and his colleagues colonized mice with streptococcal or pneumococcal bacteria, either orally or nasally. They were able to remove the colonization completely using phage enzymes delivered in a single dose.

Because these enzymes are derived from viruses that infect and kill specific bacteria, they are like smart bombs that target and kill only the species or strain of bacteria for whic
'"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
5-Aug-2004


Page: 1 2

Related biology news :

1. Viral suspect for amphibian decline traced to human spread through bait
2. Viral immunosuppression: Not just a game of hide and go seek
3. Viral protein may be associated with human brain tumors
4. Viral proteins may be associated with human brain tumors, according to findings by Temple researchers
5. New Study By TSRI Scientists Sheds Light On Viral Clearance In Acute Hepatitis B Infection
6. Viral Harpoon Structure Suggests Measles, HIV And Ebola Viruses Related
7. Antiviral From Advanced Viral Research Corp. Inhibits CCR5 Cell Receptor For HIV
8. Newly Discovered Viral Gateway Into Cells Could Play Role In Diagnosis And Treatment Of Leukemia, HIV And Other Viral Diseases
9. Novel Viral Vaccine Protects Aids In Animal Model
10. Viral Vector Delivers Dystophin Gene To Mouse Muscle
11. Experts Say That Future Inhaled Anti-Viral Drug, Zanamivir Is Effective For Treatment And Prevention Of Influenza

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... DUBLIN , Apr. 11, 2017 Research ... Tracking Market 2017-2021" report to their offering. ... The global eye tracking market to grow at ... The report, Global Eye Tracking Market 2017-2021, has been prepared based ... report covers the market landscape and its growth prospects over the ...
(Date:4/6/2017)... , April 6, 2017 ... RFID, ANPR, Document Readers, by End-Use (Transportation & Logistics, ... Facility, Oil, Gas & Fossil Generation Facility, Nuclear Power), ... Educational, Other) Are you looking for a ... sector? ...
(Date:4/5/2017)... , April 4, 2017 KEY FINDINGS ... to expand at a CAGR of 25.76% during the ... is the primary factor for the growth of the ... https://www.reportbuyer.com/product/4807905/ MARKET INSIGHTS The global stem ... technology, application, and geography. The stem cell market of ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ... any gene in its endogenous context, enabling overexpression experiments and avoiding the use ... with small RNA guides is transformative for performing systematic gain-of-function studies. , ...
(Date:10/11/2017)... ... 11, 2017 , ... ComplianceOnline’s Medical Device Summit is back for its 4th ... in San Francisco, CA. The Summit brings together current and former FDA office bearers, ... and government officials from around the world to address key issues in device compliance, ...
(Date:10/11/2017)... BioMarketing, a leading provider of patient support solutions, has announced ... network, which will launch this week. The VMS CNEs will ... to enhance the patient care experience by delivering peer-to-peer education ... professionals to help women who have been diagnosed and are ... ...
(Date:10/11/2017)... Tbilisi, Georgia (PRWEB) , ... October 11, 2017 , ... ... disaster, taking the lives of over 5.5 million people each year. Especially those living ... the greenovative startup Treepex - based in one of the most pollution-affected countries globally ...
Breaking Biology Technology:
Cached News: