HOME >> BIOLOGY >> NEWS
Virus found to carry antibiotic against E. coli

COLLEGE STATION -- Part of a small virus that attacks only bacteria acts like an antibiotic to destroy E. coli, researchers with the Texas Agricultural Experiment Station have found.

A report on the antibiotic action of the small virus, "Q Beta," is reported in this week's Science magazine. The research was funded by the National Institute of Health's general medicine institute.

The finding provides a new approach for designing drugs to combat many serious bacterial diseases, including E. coli, pneumonia, staph infection, ear infections, Lyme's disease and cholera in humans, as well as bacterial diseases in pets, livestock and crops, according to Tom Bernhardt, biochemistry doctoral student, and Dr. Ing-Nang Wang, a lead investigator on the project.

New types of antibiotics are increasingly important because many disease- causing bacteria have become resistant to antibiotics, reducing the number of medicines available for treatment. Researchers fear that continued resistance could result in epidemics of diseases once thought controlled by antibiotics.

The research at the Experiment Station found that a protein within the small virus, known as a "phage" in scientific circles, does the same thing to bacterial cell walls as antibiotics. It blocks the ability of the cell to make its tough outer wall so bacteria blow up or destroy themselves rather than divide into more cells. Dead bacterial cells means an end to the illness.

"This 'protein antibiotic' is the answer to an old mystery: how Q-beta and other small phage kill bacteria," said Dr. Ry Young, a biochemist in whose lab at Texas A&M University the work was done, in collaboration with Dr. Douglas K. Struck, a medical biochemistry and genetics professor. "Basically they let the cell commit suicide by dividing without making a new cell wall."

The research team expects pharmaceutical companies to further explore phages for new types of antibiotics. "Ideally, the small bit
'"/>

Contact: Kathleen Phillips
ka-phillips@tamu.edu
979-845-2872
Texas A&M University
21-Jun-2001


Page: 1 2

Related biology news :

1. Virus known for its photo ops makes its movie screen debut
2. Viruses clear bacterial contamination in chickens
3. Viruses may be environmentally friendly decontaminants
4. The Virus-Cancer Link: Examining the Role of Viruses in the Development of Cancer
5. Virus researchers close in on the secret life of DNA
6. Virus beats food bug
7. West Nile Virus cases analyzed for prevalence and symptoms
8. West Nile Virus can cause polio-like symptoms
9. Antibodies critical for fighting West Nile Virus infection
10. CDC Telebriefing: Smallpox educational activities and West Nile Virus update
11. West Nile Virus capsid protein causes encephalitic inflammation by triggering cell suicide

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/22/2016)... June 22, 2016   Acuant , ... verification solutions, has partnered with RightCrowd ® ... for Visitor Management, Self-Service Kiosks and Continuous ... that add functional enhancements to existing physical ... and venues with an automated ID verification ...
(Date:6/16/2016)... 2016 The global ... reach USD 1.83 billion by 2024, according to ... Technological proliferation and increasing demand in commercial buildings, ... drive the market growth.      (Logo: ... development of advanced multimodal techniques for biometric authentication ...
(Date:6/7/2016)... 2016  Syngrafii Inc. and San Antonio Credit ... includes integrating Syngrafii,s patented LongPen™ eSignature "Wet" solution ... will result in greater convenience for SACU members ... maintaining existing document workflow and compliance requirements. ... Highlights: ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Houston Methodist Willowbrook Hospital has signed ... to serve as their official health care provider. ... will provide sponsorship support, athletic training services, and ... volunteers, athletes and families. "We are ... and to bring Houston Methodist quality services and ...
(Date:6/23/2016)... FRANCISCO , June 23, 2016   EpiBiome ... has secured $1 million in debt financing from Silicon ... ramp up automation and to advance its drug development ... its new facility. "SVB has been an ... beyond the services a traditional bank would provide," said ...
(Date:6/23/2016)... , June 23, 2016 Apellis ... Phase 1 clinical trials of its complement C3 ... single and multiple ascending dose studies designed to ... (PD) of subcutaneous injection in healthy adult volunteers. ... (SC) either as a single dose (ranging from ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... the Pennsylvania Convention Center and will showcase its product’s latest features from June ... be presenting a scientific poster on Disrupting Clinical Trials in The Cloud during ...
Breaking Biology Technology:
Cached News: