Virus found to carry antibiotic against E. coli

COLLEGE STATION -- Part of a small virus that attacks only bacteria acts like an antibiotic to destroy E. coli, researchers with the Texas Agricultural Experiment Station have found.

A report on the antibiotic action of the small virus, "Q Beta," is reported in this week's Science magazine. The research was funded by the National Institute of Health's general medicine institute.

The finding provides a new approach for designing drugs to combat many serious bacterial diseases, including E. coli, pneumonia, staph infection, ear infections, Lyme's disease and cholera in humans, as well as bacterial diseases in pets, livestock and crops, according to Tom Bernhardt, biochemistry doctoral student, and Dr. Ing-Nang Wang, a lead investigator on the project.

New types of antibiotics are increasingly important because many disease- causing bacteria have become resistant to antibiotics, reducing the number of medicines available for treatment. Researchers fear that continued resistance could result in epidemics of diseases once thought controlled by antibiotics.

The research at the Experiment Station found that a protein within the small virus, known as a "phage" in scientific circles, does the same thing to bacterial cell walls as antibiotics. It blocks the ability of the cell to make its tough outer wall so bacteria blow up or destroy themselves rather than divide into more cells. Dead bacterial cells means an end to the illness.

"This 'protein antibiotic' is the answer to an old mystery: how Q-beta and other small phage kill bacteria," said Dr. Ry Young, a biochemist in whose lab at Texas A&M University the work was done, in collaboration with Dr. Douglas K. Struck, a medical biochemistry and genetics professor. "Basically they let the cell commit suicide by dividing without making a new cell wall."

The research team expects pharmaceutical companies to further explore phages for new types of antibiotics. "Ideally, the small bit

Contact: Kathleen Phillips
Texas A&M University

Page: 1 2

Related biology news :

1. Virus known for its photo ops makes its movie screen debut
2. Viruses clear bacterial contamination in chickens
3. Viruses may be environmentally friendly decontaminants
4. The Virus-Cancer Link: Examining the Role of Viruses in the Development of Cancer
5. Virus researchers close in on the secret life of DNA
6. Virus beats food bug
7. West Nile Virus cases analyzed for prevalence and symptoms
8. West Nile Virus can cause polio-like symptoms
9. Antibodies critical for fighting West Nile Virus infection
10. CDC Telebriefing: Smallpox educational activities and West Nile Virus update
11. West Nile Virus capsid protein causes encephalitic inflammation by triggering cell suicide

Post Your Comments:

(Date:11/12/2015)... Mass. , Nov. 12, 2015  Arxspan ... Institute of MIT and Harvard for use of ... discovery information management tools. The partnership will support ... both biological and chemical research information internally and ... will be used for managing the Institute,s electronic ...
(Date:11/11/2015)... Nov. 11, 2015   MedNet Solutions , an innovative ... clinical research, is pleased to announce that it will be ... (PCT) event, to be held November 17-19 in ... view live demonstrations of iMedNet , MedNet,s ... iMedNet has been able to deliver time and ...
(Date:11/10/2015)... Nov. 10, 2015 About ... that helps to identify and verify the identity ... considered as the secure and accurate method of ... a particular individual because each individual,s signature is ... especially when dynamic signature of an individual is ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... 24, 2015 Cepheid (NASDAQ: CPHD ) ... the following conference, and invited investors to participate via ...      Tuesday, December 1, 2015 at 11.00 a.m. Eastern ...      Tuesday, December 1, 2015 at 11.00 a.m. Eastern ... New York, NY      Tuesday, December 1, ...
(Date:11/24/2015)... ... November 24, 2015 , ... ... year and one of the premier annual events for pharmaceutical manufacturing: 2015 Annual ... November 2015, where ISPE hosted the largest number of attendees in more than ...
(Date:11/24/2015)... PHILADELPIA, PA (PRWEB) , ... November 24, 2015 , ... ... young entrepreneurs at competitive events in five states to develop and pitch their BIG ... student projects from each state are competing for votes to win the title of ...
(Date:11/24/2015)... Nov. 24, 2015  Tikcro Technologies Ltd. (OTCQB: TIKRF) today announced that ... 2015 at 11:00 a.m. Israel time, at the ... Yigal Allon Street, 36 th Floor, Tel Aviv, Israel ... Paneth and Izhak Tamir to the Board of Directors; ... external directors; , approval of an amendment to certain terms of ...
Breaking Biology Technology:
Cached News: