HOME >> BIOLOGY >> NEWS
Viruses help strep bacteria turn deadly

A common bacterium can turn into a potent killer if it picks up the right set of genes, but how and when those genes are acquired has remained poorly understood. In a new study, researchers show that special viruses are the culprits behind the emergence of virulent select new bacterial strains. Those viruses, called bacteriophages, specifically infect bacteria, capture some of their genes, and transfer the genes from one microbe to the next. By moving genes among their hosts, bacteriophages can create new bacterial strains with potentially deadly properties. The discovery, which will reported this week in the online edition of Proceedings of the National Academy of Sciences, highlights an important mechanism for bacterial evolution and identifies several potential targets for vaccines or drugs to prevent or treat some severe infections.

Group A Streptococcus (GAS) bacteria are common microbes that cause many different diseases, including strep throat, wound infections, toxic shock, "flesh-eating" disease, scarlet fever, rheumatic fever and kidney ailments. James Musser, M.D., Ph.D., of the National Institute of Allergy and Infectious Diseases (NIAID), seeks to understand why some GAS strains cause severe infections while others lead to milder illnesses. To accomplish that goal, he and his collaborators have turned to the GAS genome. By comparing the complete genetic blueprints of bacterial strains isolated from people with different GAS infections, the researchers hope to identify specific genes linked with individual diseases.

"We are trying to move past the technical phase of genome research and start using what we have learned from gene sequences to develop new ways to prevent and treat infections and to understand how new, virulent strains emerge," says Dr. Musser, who directs the human bacterial pathogenesis laboratory at NIAID's Rocky Mountain Laboratories in Hamilton, Mont.

In their most recent study, Dr. Musser, Stephen Beres
'"/>

Contact: Sam Perdue
sp189u@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
15-Jul-2002


Page: 1 2

Related biology news :

1. Viruses clear bacterial contamination in chickens
2. Viruses may be environmentally friendly decontaminants
3. The Virus-Cancer Link: Examining the Role of Viruses in the Development of Cancer
4. Viruses concentrate
5. American Red Cross Launches New Genetic Screening Technology To Directly Detect Viruses
6. Viral Harpoon Structure Suggests Measles, HIV And Ebola Viruses Related
7. Antibody Revolution Targets STDs, Stomach Viruses, Common Cold
8. Cellular Target Of Leprosy, Deadly Viruses Found
9. New Evidence Shows How Some Flu Viruses Become Lethal
10. University of Florida Researchers Develop Filter Coating That Traps Bacteria and Viruses
11. Inter-Element Recombination Between Retrotransposons May Be Strategy For Evolution Of Viruses Like HIV

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/7/2019)... ... 2019 , ... R3 Stem Cell is now offering its comprehensive Online ... code to use during checkout is FIFTYOFF and applies to both the one month ... regenerative therapies with over 12,000 successful stem cell procedures performed nationwide. A couple years ...
(Date:11/5/2019)... ... November 05, 2019 , ... Catalent, the ... biologics, gene therapies, and consumer health products, today announced it will present at ... Spain on Nov. 12 – 14, 2019. , On Wednesday, Nov. 13 at ...
(Date:10/30/2019)... ... 29, 2019 , ... LGC Maine Standards releases VALIDATE® UC1 ... 701sa & 704sa. The kits, in a human-urine matrix, evaluate CA, CL, CREA, ... kit, liquid, ready-to-use, and prepared using the CLSI EP06-A “equal delta” sample preparation, ...
Breaking Biology News(10 mins):
(Date:11/12/2019)... ... November 12, 2019 , ... Bode Technology ... of Forensic Genealogy, Melinde Lutz Byrne, to the organization. Byrne’s team will strengthen ... investigative leads to law enforcement through proven genealogy and DNA analysis methods. , ...
(Date:11/5/2019)... , ... November 04, 2019 ... ... of advanced delivery technologies, development, and manufacturing solutions for drugs, biologics, gene ... cell line development technology, GPEx® Boost. The technology enhances Catalent’s proven GPEx ...
(Date:11/2/2019)... ... October 31, 2019 , ... drug360 graph, a breakthrough knowledge ... drug360 brings tellic’s expertise in biomedical language processing and machine learning to bear ... between genes, diseases, variants, phenotypes, and other biomedical entities. Researchers and analysts ...
(Date:10/29/2019)... ... October 29, 2019 , ... Researchers ... Using Silios CMS-C multispectral imagers , researchers identified people by the image ... based on retinal imaging, face recognition, fingerprints and vasculature. , The new ...
Breaking Biology Technology:
Cached News: