HOME >> BIOLOGY >> NEWS
Visualizing Alzheimer's disease

New Orleans, Nov. 12, 2003 -- Using recently developed techniques for imaging individual cells in living animals, a team led by researchers at Washington University School of Medicine in St. Louis has watched as Alzheimer's-like brain plaques damage mouse brain cells.

The results will be presented at 9 a.m. CT on Wednesday, Nov. 12, at the 33rd Annual Meeting of the Society for Neuroscience in New Orleans.

"This work is very exciting," says principal investigator David M. Holtzman, M.D. "We've been able to visualize damaged nerve connections in living animals and follow them over time in the same animal. Our next step is to determine whether such damage is reversible."

Holtzman is the Andrew B. and Gretchen P. Jones Professor of Neurology and head of the Department of Neurology, the Charlotte and Paul Hagemann Professor of Neurology and a professor of molecular biology and pharmacology. The first author is Robert P. Brendza, Ph.D., research instructor in neurology.

The study was conducted in collaboration with Brian Bacskai, Ph.D., investigator at Massachusetts General Institute for Neurodegenerative Disorders and an assistant professor of neurology at Harvard Medical School; and Bradley Hyman, M.D., Ph.D., director of the Alzheimer's Unit at the Massachusetts General Institute for Neurodegenerative Disorders; and John B. Penney Jr. Professor of Neurology at Harvard Medical School; William E. Klunk, M.D., Ph.D., director of psychiatry of the Alzheimer's Disease Research Center at the University of Pittsburgh; and Kelly Bales, senior biologist, and Steven Paul, M.D., executive vice president for science and technology at Eli Lilly and Co.

In the 1990s, biologists discovered the protein that makes certain jellyfish luminescent also could be used to generate fluorescent cells in other species. By shining light on a living mouse engineered to contain these proteins, researchers can watch cellular activity over time using a multi
'"/>

Contact: Gila Z. Reckess
reckessg@wustl.edu
314-286-0109
Washington University School of Medicine
12-Nov-2003


Page: 1 2

Related biology news :

1. Visualizing the central dogma
2. Visualizing protein synthesis in living neurons
3. Alzheimers disease is not accelerated aging
4. Study explores gene transfer to modify underlying course of Alzheimers disease
5. TANGO: towards faster prognosis of Alzheimers and Parkinsons diseases?
6. DHA-rich diet protects brain from Alzheimers damage, UCLA study shows
7. Decreasing toxins in brains of Alzheimers patients keep cognitive deficits at bay
8. Early clinical treatment can halt progression of Alzheimers disease, UCI researchers find
9. New UCF researchers, college will help fight Alzheimers disease, cancer
10. Herpes tool allows researchers to customize Alzheimers vaccine
11. Altered protein involved in a novel link to Alzheimers disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: