HOME >> BIOLOGY >> NEWS
Vitamin C produces gene-damaging compounds, test-tube study in Science reports

Vitamin C, known to be a DNA-protecting "antioxidant," is a switch hitter, also capable of inducing the production of DNA-damaging compounds, suggests a study in the 15 June issue of the international journal, Science. Mutations caused by these compounds have been found in a variety of tumors.

Such mutations can be repaired, however, and lead author Ian Blair of the Center for Cancer Pharmacology, at the University of Pennsylvania, cautioned that the study shouldn't be interpreted as a claim that vitamin C causes cancer. Nor does it question the wisdom of eating a balanced diet rich in fruits, vegetables, and whole grains, he said.

The findings, which come from test-tube experiments (in vitro), may help explain why vitamin C has thus far shown little effectiveness at preventing cancer in clinical trials, according to the Science authors.

"It's possible that vitamin C isn't working in cancer prevention studies because it's causing as much damage as it's preventing, but that's really speculation at this point. What we can say is that vitamin C clearly doesn't work when you expect it to, and now we're in a position to see if that's what's happening in vivo, [or, in living cells]" Blair said.

Some scientists have long recommended dietary supplements of vitamin C, particularly for treating and preventing cancer. But the supplements' effectiveness has been hotly debated, with critics saying they either have no effect or that they may be harmful.

"The logic being used [for vitamin C supplements] is that 'fruits, vegetables, etc. contain vitamin C; these foods prevent cancer; thus vitamin C prevents cancer," Blair said. "But our message is that it's the total diet that's important, not just one antioxidant in isolation."

Vitamin C is known to do beneficial work in the body, including acting as an antioxidant that "disarms" free radicals. These highly reactive ions are produc
'"/>

Contact: Cherita Gonzales
cgonzale@aaas.org
202-326-6414
American Association for the Advancement of Science
14-Jun-2001


Page: 1 2

Related biology news :

1. Vitamins do little to prevent recurrent stroke
2. Vitamin C may protect against ulcer-causing bacteria, study finds
3. Vitamin D analog found to boost radiation
4. As Vitamin B-6 levels go down, numbers of DNA strand breaks go up
5. UC Riverside biochemists develop technology to increase Vitamin C in plants
6. Vitamin D may be crucial in preventing colon cancer
7. Vitamin C transporter gene discovery in mice
8. Vitamin E and aspirin delay heart disease in mice even with high cholesterol levels
9. Rat genes increase Vitamin C in plants
10. Penn study finds signs folic acid and Vitamin B12 may lessen some ill effects of SMA
11. Vitamin deficiency may exacerbate motor neuron disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/30/2020)... ALAMOS, N.M. (PRWEB) , ... April 28, 2020 , ... ... of the world’s biggest challenges in agriculture and aquaculture with the mission of improving ... presenters at the 2020 F&A Next ' Next Heroes in Food- and Ag-Tech ' ...
(Date:4/28/2020)... ... April 27, 2020 , ... ... service was started by three teenagers with an idea to help millions of ... during the time of great need and suffering, an outlet has been created ...
(Date:4/23/2020)... FRANKLIN, Wis. (PRWEB) , ... April 23, 2020 ... ... with its expansion and recruitment plans. MDG provides critical infrastructure products for the ... to push MDG’s previous plans for expansion. Further, as supply channels from overseas ...
Breaking Biology News(10 mins):
(Date:5/21/2020)... Eden Prairie, MN (PRWEB) , ... May 19, 2020 , ... ... solution to help patients get dental implants and bone grafting through PIEZOSURGERY® ... surrounding tissues. This is often used to prepare a patient for dental implants, especially ...
(Date:5/15/2020)... Mass. (PRWEB) , ... May 14, 2020 , ... ... but to undergo multiple open heart surgeries before becoming adults. The ... , To address this critical unmet need, the Department of Defense has ...
(Date:5/14/2020)... , ... May 12, 2020 , ... ... for translational research, is bringing together thousands of industry leaders, clinicians, research scientists, ... highlights two plenary speakers, Carl June, MD, Director of the Center for Cellular ...
(Date:5/5/2020)... (PRWEB) , ... May 04, 2020 , ... ... process solutions for the life sciences industry, today announced that Informa Training Partners, ... officially changing its name to Red Nucleus Boston, effective immediately. , “The name ...
Breaking Biology Technology:
Cached News: