HOME >> BIOLOGY >> NEWS
Vitamin D deficiency and bowel diseases connected

Research with mice at Penn State has demonstrated a connection between vitamin D deficiency and two bowel diseases that occur in one out of every 1,000 people in North America and Europe.

Dr. Margherita T. Cantorna, assistant professor of nutrition and director of the research project, says "Our experiments show that vitamin D deficiency worsens the symptoms of Chron's disease and ulcerative colitis. Treatment with Vitamin D for as little as two weeks lessens the symptoms of these inflammatory bowel diseases in mice."

Cantorna detailed her research in a paper, "Vitamin D Deficiency Exacerbates Experimental Inflammatory Bowel Disease," presented today (April 18) at the Experimental Biology conference in San Diego, Calif. Her co-authors are Carey Munsick, a Penn State undergraduate, and Candace Bemiss, a Penn State master's degree candidate in nutrition. Their paper is the first in which researchers report demonstrating a connection between vitamin D deficiency and inflammatory bowel disease (IBD).

In her team's experiments, mice genetically engineered to spontaneously develop the symptoms of either Chron's disease or ulcerative colitis were also made vitamin D deficient at birth. The mice were then either maintained deficient or given vitamin D supplements in their food to bring them up to the normal level. The treated mice had less bowel inflammation than the untreated mice did. In addition, the mice that did not receive the supplements began to die at seven weeks of age and by nine weeks more than half were dead. In contrast none of the mice that received the supplements died during the experiment period.

"Vitamin D deficiency is more common in people who have inflammatory bowel disease. In addition, the anti-inflammatory drugs often used to treat IBD can cause bone loss as a side effect," Cantorna says. "Vitamin D taken in combination with these drugs may be able to reduce the effective dose of anti-inflammatory needed to tr
'"/>

Contact: Barbara Hale
bah@psu.edu
814-865-9481
Penn State
17-Apr-2000


Page: 1 2 3

Related biology news :

1. Vitamins do little to prevent recurrent stroke
2. Vitamin C may protect against ulcer-causing bacteria, study finds
3. Vitamin D analog found to boost radiation
4. As Vitamin B-6 levels go down, numbers of DNA strand breaks go up
5. UC Riverside biochemists develop technology to increase Vitamin C in plants
6. Vitamin D may be crucial in preventing colon cancer
7. Vitamin C transporter gene discovery in mice
8. Vitamin E and aspirin delay heart disease in mice even with high cholesterol levels
9. Rat genes increase Vitamin C in plants
10. Vitamin C produces gene-damaging compounds, test-tube study in Science reports
11. Penn study finds signs folic acid and Vitamin B12 may lessen some ill effects of SMA

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/29/2016)... Nearly one billion matches per second with DERMALOG,s high-speed AFIS    ... ... DERMALOG is Germany's largest Multi-Biometric supplier: The company's Fingerprint ... ... Multi-Biometric supplier: The company's Fingerprint Identification System is part of an efficient ...
(Date:11/22/2016)... According to the new market research report "Biometric System Market by ... Component (Hardware and Software), Function (Contact and Non-contact), Application, and Region - ... grow from USD 10.74 Billion in 2015 to reach USD 32.73 Billion ... Continue Reading ... ...
(Date:11/19/2016)... 18, 2016 Securus Technologies, a leading provider ... safety, investigation, corrections and monitoring, announced today that it ... to have an independent technology judge determine who has ... high tech/sophisticated telephone calling platform, and the best customer ... do most of what we do – which clearly ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... ... 2016 , ... Orthogonal, a Chicago-based medical device software company, ... 510(k) clearance for their flagship medical device, SimplECG. , With this FDA approval, ... rely on cloth-based nanosensors. While other companies have attempted to focus on wearable ...
(Date:12/2/2016)... ... December 02, 2016 , ... Robots will storm the Prudential ... December 3rd, 2016. The event, which is held on the United Nations International Day ... with Disabilities back into the workplace. Suitable Technologies is partnering with NTI to showcase ...
(Date:12/2/2016)... The immunohistochemistry (IHC) market is projected ... of 7.3% during the forecast period of 2016 to 2021 dominated ... accounted for the largest share of immunohistochemistry (IHC) market, by end ... , , ... market spread across 225 pages, profiling 10 companies and supported with ...
(Date:11/30/2016)... ... 30, 2016 , ... BEI Kimco, a brand of Sensata ... design that ensures high alignment accuracy by preventing unwanted shaft rotation. The new ... extreme precision is required, such as in medical equipment, laboratory instrumentation, clean rooms, ...
Breaking Biology Technology:
Cached News: