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Vitamins do little to prevent recurrent stroke

ary heart disease "event," usually a heart attack, compared to 6.3 percent of patients on the high dose. Overall deaths from any cause totaled 5.4 percent of the high-dose group compared to 6.3 percent of the low-dose group.

Just after the start of VISP, folate fortification of the U.S. grain supply began (which increased folic acid in breads and other foods containing grains) and it became mandatory in January 1998. This "profoundly reduced" the number of people with low levels of folate and high total homocysteine levels, Toole said.

The study was stopped in December 2002, when the study's performance and safety monitoring board told the funding agency, the National Institute of Neurological Disorders and Stroke, that "there was no chance of showing any difference between the two treatment groups during the remaining follow-up period."


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Contact: Robert Conn
rconn@wfubmc.edu
336-716-4587
Wake Forest University Baptist Medical Center
3-Feb-2004


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