HOME >> BIOLOGY >> NEWS
Weird Creatures Have Some Lessons For Organ Transplants

TAKING a tip from tiny animals that can live for more than a century, Japanese researchers have invented a new technique for storing human organs for transplant.

The team, which has successfully revived a rat's heart after 10 days in storage, says the work may lead to organ banks similar to blood banks. These would allow doctors to avoid the frantic dash to bring suitable organs straight from donors to the operating table.

Organs can usually be stored for only 30 hours before they have to be used. For hearts and lungs, the time limit is even less-just 4 hours. The main problem with keeping organs in cold storage is that water damages cell membranes at low temperatures. Unfortunately, removing water from tissues usually causes at least as much damage.

But Kunihiro Seki and his colleagues at Kanagawa University in Hiratsuka-shi, Japan, knew that animals called tardigrades can withstand extreme conditions by losing most of the water in their bodies (In Brief, 31 October, p 26). They can survive in this state for a century or more. When water was added to a dried-out moss kept in a museum for 120 years, tardigrades were later found crawling all over it.

To achieve this feat, tardigrades use a sugar called trehalose to stabilise the structure of their cell membranes. "This suggested that the physiological mechanism for preservation and resuscitation of tardigrades could be applied to the preservation of mammalian organs," says Seki.

To test this, the team flushed rat hearts with trehalose solution before packing them in silica gel to remove the water from their cells. The hearts were then immersed in perfluorocarbon, a biologically inert compound, and stored at 4 C in airtight jars. Ten days later, the team took the hearts out of the jars and resuscitated them. Within half an hour, they were beating again. Measurements of their electrical activity suggested that the heart cells had survived intact.

Sek
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-171-331-2751
New Scientist
4-Nov-1998


Page: 1 2

Related biology news :

1. Lessons from abroad: United States trails Europe in dependence on renewable energy
2. USGS Scientists Learn Lessons From Captive Released Manatees
3. Biosphere Lessons Can Be Applied To Space, Former Crew Co-Captain Says
4. Organization for Human Brain Mapping 2004 Annual Meeting
5. Office Depot partners with Conservation Organizations to incorporate science into paper procurement
6. Organization for Human Brain Mapping annual meeting abstract highlights
7. Organelles discovery challenges theory, could alter approach to disease treatment
8. Organization for Human Brain Mapping 2003 Annual Meeting
9. Organic and sustainable foods have more polyphenolics linked to health benefits
10. Organic & Biomolecular Chemistry
11. HHMI awards $2 million to European Molecular Biology Organization

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... 30, 2017  On April 6-7, 2017, Sequencing.com will ... hackathon at Microsoft,s headquarters in ... focus on developing health and wellness apps that provide ... the Genome is the first hackathon for personal ... largest companies in the genomics, tech and health industries ...
(Date:3/28/2017)... , March 28, 2017 ... Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video ... and Region - Global Forecast to 2022", published by ... in 2016 and is projected to reach USD 75.64 ... 2017 and 2022. The base year considered for the ...
(Date:3/23/2017)... March 23, 2017 The report "Gesture Recognition and Touchless ... and Geography - Global Forecast to 2022", published by MarketsandMarkets, the market is ... of 29.63% between 2017 and 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... ... wash is a basic first aid supply for any work environment, but most personal eye ... first if a dangerous substance enters both eyes? It’s one less decision, and likely quicker ... eye piece. , “Whether its dirt and debris, or an acid or alkali, getting anything ...
(Date:10/11/2017)... ... , ... Disappearing forests and increased emissions are the main causes of the ... Especially those living in larger cities are affected by air pollution related diseases. , ... pollution-affected countries globally - decided to take action. , “I knew I had to ...
(Date:10/10/2017)... (PRWEB) , ... October 10, 2017 , ... ... Science Center’s FirstHand program has won a US2020 STEM Mentoring Award. Representatives of ... award for Excellence in Volunteer Experience from US2020. , US2020’s mission is to ...
(Date:10/10/2017)... PITTSBURGH, PA (PRWEB) , ... October 10, 2017 ... ... this year’s recipients of 13 prestigious awards honoring scientists who ... be presented in a scheduled symposium during Pittcon 2018, the world’s leading conference ...
Breaking Biology Technology:
Cached News: