Welch Award honors McConnell for insights into physical chemistry, cell membranes

ear magnetic resonance (NMR) data to the structure of molecules. He modified the equations governing NMR to include the effects of chemical reactions, and used the results to measure chemical kinetics, i.e., the speed at which reactions take place. He has also pioneered research on free radicals an extremely reactive type of chemical that occurs in chemical and biological settings; this ultimately led to the development of the McConnell Relation, which describes the distribution of electron spin in free radicals.

When Dr. McConnell moved to Stanford University in 1964, he began to use the methods of physical chemistry to study biological problems. There, he introduced a method called spin labels, in which electron and NMR spectra are used to study the structure and kinetics of proteins and lipids. His work showed how to measure the movement of molecules through and within membranes in the laboratory; this was later shown by many researchers to apply to living cell membranes. His research also showed how a protein present in the body combines with that of a foreign peptide on the cell membrane to enable the body to recognize a pathogenic invader.

Some of these discoveries are critical to understanding many properties of membranes, says Dr. McConnell, and a large portion of biology takes place in and on membranes, so understanding them is crucial.

Dr. McConnells recent work has focused on the behavior of cholesterol in membranes. Discoveries by his team concerning the properties of monomolecular films on the surface of water have shed light on cholesterol-phospholipid interactions that previously had puzzled scientists in several different fields of research.

Cholesterol forms special condensed complexes, says Dr. McConnell. By describing them mathematically, one can predict many of the properties that have been observed regarding cholesterol and phospholipid mixtures, which are major components of animal cell membranes. He believes th

Contact: Melissa Quiroz
The Welch Foundation

Page: 1 2 3

Related biology news :

1. Harden McConnell named winner of 2002 Welch Award in Chemistry
2. Welch honors Kornberg for insights into DNA transcription
3. Welch Award honors 2 for unlocking natures secrets
4. Gladstone investigator Mike McCune wins prestigious NIH Directors Pioneer Award
5. UT Southwestern biochemist honored with NIH Directors Pioneer Award
6. Award winning researchers reveal potential new role for Glivec
7. UMaine anthropologist wins Solon T. Kimball Award
8. Secretary of Energy announces seven E.O. Lawrence Award Winners
9. Martin Saunders to receive the James Flack Norris Award
10. Berkeley Lab soil scientist Margaret Torn receives Presidential Early Career Award
11. NJIT professor receives Presidential Award for breakthrough research with adult stem cells

Post Your Comments:

(Date:4/11/2017)... NXT-ID, Inc. (NASDAQ:   NXTD ) ... appointment of independent Directors Mr. Robin D. Richards ... Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , Chief Executive ... their guidance and benefiting from their considerable expertise as we ...
(Date:4/5/2017)... , April 5, 2017 Today HYPR ... that the server component of the HYPR platform is ... providing the end-to-end security architecture that empowers biometric authentication ... HYPR has already secured over 15 million users across ... manufacturers of connected home product suites and physical access ...
(Date:4/3/2017)... WASHINGTON , April 3, 2017 /PRNewswire-USNewswire/ ... single-cell precision engineering platform, detected a statistically ... cell product prior to treatment and objective ... highlight the potential to predict whether cancer ... prior to treatment, as well as to ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... ... company advancing targeted antibody-drug conjugate (ADC) therapeutics, today confirmed licensing rights that ... Polymerized Liposomal Nanoparticle), a technology developed in collaboration with Children’s Hospital Los ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... optimization firm for the life sciences and healthcare industries, announces a presentation by ... Francisco. , The presentation, “Automating GxP Validation for Agile Cloud Platforms,” will present ...
(Date:10/9/2017)... ... October 09, 2017 , ... The Giving ... marijuana products targeting the needs of consumers who are incorporating medical marijuana into ... in Phoenix, Arizona. , As operators of two successful Valley dispensaries, The Giving ...
(Date:10/6/2017)... ... October 06, 2017 , ... The HealthTech Venture ... sector at their fourth annual Conference where founders, investors, innovative practitioners and collaborators ... ELEVATE pitch competition showcasing early stage digital health and med tech companies. , ...
Breaking Biology Technology:
Cached News: