HOME >> BIOLOGY >> NEWS
Whitehead Receives $7 million NIH Grant To Build High-Speed Sequencing Machines

The Whitehead Institute for Biomedical Research has received a three-year, $7 million grant from the National Human Genome Research Institute to develop chip- based genome sequencing machines that can sequence 7 million DNA letters per day, or 2 billion letters per year. Once these machines are up and running, it would be possible to use as few as 20 machines to sequence an entire mammalian genome in one year, according to Whitehead scientists.

Slated for introduction into NIH genome laboratories in three years, these machines will accelerate the U.S. Human Genome Project's efforts to sequence the entire 3 billion DNA letters that make up a human being by year 2003. They also will reduce the cost of the capital equipment for future facilities by a factor of ten. Scientists anticipate that the need for cost-effective DNA sequencing machines will continue to increase in the new millennium as applications of the Genome Project extend into biomedicine.

The proposed sequencing machines will incorporate a microfabricated "chip" device that miniaturizes the process of electrophoresis, the method currently used to read DNA landmarks. The device can sequence DNA at 10 times the speed of existing commercial technology, and it is completely automated, eliminating the need for tedious labor. The machines will be 10 to 20 times more productive than the systems announced by Perkin Elmer and Celera corporation. In addition, the Whitehead Institute machines will be geared to read significantly longer stretches of DNA--crucial to reduce the time it takes to piece together overlapping fragments.

"This project is a collaborative effort between the Whitehead Institute BioMEMS Engineering Group, and the Whitehead/MIT Center for Genome Research," says Dr. Paul Matsudaira, Member of the Whitehead Institute. "Our goal is to create, on a rapid timetable, a transferable technology that can substantially accelerate the efforts of NIH Genome Centers to sequence the h
'"/>

Contact: Seema Kumar or Eve Nichols
kumar@wi.mit.edu or nichols@wi.mit.edu
617-258-5183
Whitehead Institute for Biomedical Research
12-Mar-1999


Page: 1 2 3

Related biology news :

1. Whitehead press seminar 2001: new horizons in the post-genome world
2. Whitehead Institute receives National Science Foundation grant to sequence Neurospora
3. Whitehead press seminar: Beyond the scientific frontier
4. Millennium and the Whitehead Institute identify novel protein important in fat absorption
5. Whitehead Receives $35 Million Grant From National Human Genome Research Institute (NHGRI)
6. Whitehead Study Supports Existence Of Ancient RNA World, Helps Provide Insight Into Early Evolution Of Life
7. Whitehead Study Establishes Role Of DNA Methylation In The Stability Of DNA, Suggests Possible Role Of Undermethylation In Cancer
8. Stanford Chemical Engineer Chaitan Khosla Receives Alan T. Waterman Award From NSF
9. UCSFs Elizabeth Blackburn Receives Two Major Science Awards
10. Wildlife Conservation Society Receives $700,000 Grant From Doris Duke Charitable Foundation
11. Ohio State Professor Receives Patent For Infectious Bursal Disease Virus Detection Kit

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/11/2020)... (PRWEB) , ... February 11, ... ... dedicated to solving complex problems for life sciences companies and government agencies, ... 30 years of management consulting expertise to Tunnell, with significant experience assessing, ...
(Date:2/6/2020)... ... 06, 2020 , ... Kerafast Inc. , developers of ... announced an agreement with The Good Food Institute , a nonprofit organization ... partnership, terrestrial meat and aquatic cell lines will be made available to scientists ...
(Date:1/29/2020)... , ... January 29, 2020 , ... ... the new Analytics and Data Sciences practice, providing consulting services for strategy, research ... was announced by Mike Townley, co-founder and Managing Partner of CREO, an innovative ...
Breaking Biology News(10 mins):
(Date:1/22/2020)... ... 21, 2020 , ... Microbial Discovery Group LLC (MDG) is ... and Institutional (I&I) Account Manager. Darrell will focus on servicing MDG’s partners with ... 30 years of sales experience working across multiple different market sectors such as; ...
(Date:1/10/2020)... ... January 09, 2020 , ... A new report from ... vendor qualification process, a critical element of clinical trial set up and execution. ... vendor qualification process creates delays in initiation in 7% of clinical trials for ...
(Date:1/8/2020)... SHREWSBURY, Mass. (PRWEB) , ... January 08, 2020 ... ... engineered clad metal wire composites that can achieve specific properties for use in ... Composite Clad Metal Wire combines up to three metals or alloys to ...
(Date:1/7/2020)... N.J. (PRWEB) , ... January 07, 2020 , ... Vuja ... prevent cancer progression and recurrence, today announced the appointments of Chand Khanna, DVM, PhD, ... Co-founder and CEO of Vuja De said, “We are delighted to welcome Chand and ...
Breaking Biology Technology:
Cached News: