HOME >> BIOLOGY >> NEWS
Why does caffeine delay exercise-induced fatigue?

If the researchers were correct, the CNS administration of caffeine will increase run time to fatigue, whereas NECA will reduce run time to fatigue. Furthermore, pretreatment with caffeine before NECA will weaken the fatigue-inducing effects of NECA.

The authors of "Central Nervous System Effects of Caffeine and Adenosine on Fatigue," are J. Mark Davis, Zuowei Zhao, Howard S. Stock, Kristen A. Mehl, James Buggy, and Gregory A. Hand, all from the Schools of Public Health and Medicine, University of South Carolina, Columbia, SC. Their findings appear in the February 2003 edition of the American Journal of Physiology Regulatory, Integrative and Comparative Physiology. The journal is one of 14 peer-reviewed publications produced monthly by the American Physiological Society (APS).

Methodology

Male Wistar rats, five weeks old and weighing 200-250 grams, were used in this study, and randomly assigned to intracerebroventricular or intraperitoneal injection groups. Rats were given two weeks of treadmill acclimation of running for 15 minutes a day. The treadmill speed was slowly increased from eight meters a minute, 7.5 percent grade at the beginning, progressing to 20 meters a minute at the end of the acclimation period. Gentle hand prodding and mild electric shock were combined to encourage the animals to run throughout the study.

After the first two weeks of acclimation, rats assigned to the intracerebroventricular group were anesthetized with pentobarbital sodium, and tubes were implanted bilaterally into the lateral ventricles. After seven days of recovery from surgery, the rats were again acclimated to treadmill running for another one to two weeks, until they were able to run easily for at least 15 minutes per day for 5 consecutive days at a speed of 20 meters a minute at a 7.5 percent grade. Animals that were unable to run at that pace were excluded.

Four drug treatments were used in the study: NECA, caffeine, caffeine
'"/>

Contact: Donna Krupa
djkrupa1@aol.com
703-527-7357
American Physiological Society
18-Mar-2003


Page: 1 2 3 4

Related biology news :

1. Why some neonates need caffeine
2. Researchers study metabolic, cardiovascular effects of caffeine consumed with naringin
3. The genetic basis for caffeine-induced anxiety discovered
4. UT Southwestern scientist explores caffeine-signaling activity in brain function
5. Findings conclude sustained caffeine intake negates the benefits of creatine supplements
6. Medicines, caffeine and antibacterial soap among contaminants found in American streams
7. Moderate caffeine use does not increase miscarriage risk but high caffeine use doubles risk
8. Pollutant causes delayed flowering in plants
9. Mammoths stranded on Bering Sea island delayed extinction
10. Pesticide delays sexual maturation
11. Genetics mutations resulting in delayed puberty are focus of MCG study

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... March 24, 2017 The Controller General of Immigration ... Abdulla Algeen have received the prestigious international IAIR Award for ... Continue Reading ... ... Deputy Controller Abdulla Algeen (small picture on the right) have received the ...
(Date:3/23/2017)... DUBLIN , Mar. 23, 2017 Research ... Anti-Theft System Market Analysis & Trends - Industry Forecast to 2025" ... ... to grow at a CAGR of around 8.8% over the next ... This industry report analyzes the market estimates and forecasts for all ...
(Date:3/22/2017)... March 21, 2017 Vigilant Solutions , ... law enforcement agencies, announced today the appointment of retired ... of public safety business development. Mr. Sheridan ... experience, including a focus on the aviation transportation sector, ... recent position, Mr. Sheridan served as the Aviation Liaison ...
Breaking Biology News(10 mins):
(Date:4/27/2017)... and RESEARCH TRIANGLE PARK, N.C. ... Corporation (NASDAQ: UTHR ) today announced that ... to $250 million of the company,s common stock. This ... through December 31, 2017. Purchases may be made in ... negotiated transactions from time to time as determined by ...
(Date:4/27/2017)... ... April 27, 2017 , ... This month ... (eConsent) solution that simplifies research studies, accelerates study startup, and improves participant engagement. ... Consent™ is the first and only IRB-integrated eConsent solution . , “Our ...
(Date:4/27/2017)... (PRWEB) , ... April 27, ... ... today announced a comprehensive rebrand and a name change to Fluence Analytics. ... industrial and laboratory monitoring of polymer and biopharmaceutical manufacturing processes and R&D ...
(Date:4/27/2017)... April 27, 2017  Kinexum, a distinguished resource for ... announces the appointment of Thomas C. Seoh ... Fleming, M.D., Kinexum founder, who becomes Executive Chairman and ... Kinexum clients. Thomas Seoh commented, ... Kinexum mission and lead the firm,s remarkable team of ...
Breaking Biology Technology:
Cached News: