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Women are more likely to suffer recurrent miscarriages if their first child is a boy

reject the theory of an impact of male specific antigens on the reproductive performance of women with SRM."

However Dr Christiansen believes his theory is probably correct because he has conducted two placebo-controlled trials in which infusions of intravenous immunoglobulin have been given to women with SRM to try to make their immune systems tolerate the male-specific antigens. This treatment increased the live birth rate by a factor of 2.3, whereas no effect could be detected in women who had never had a child and who suffered recurrent miscarriages.

"For many years it has been well-known that pregnancies with boys carry an increased risk for a long series of obstetrical complications compared with girl pregnancies. We believe that our research will be able to clarify whether these complications may be related to immunization against male-specific antigens. If this turns out to be the case, then I believe that we already have a quite efficient treatment, as our trials have shown."


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Contact: Emma Mason
wordmason@aol.com
44-0-1376-563090
European Society for Human Reproduction and Embryology
1-Jul-2003


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