HOME >> BIOLOGY >> NEWS
World's first 'robot scientist' proves a major success in the lab

A "robot scientist" that generates hypotheses about the function of particular genes in baker's yeast - and then designs and carries out experiments to test them - has been developed by a team of British scientists, according to new research published in the journal Nature today [14 January 2004].

"This research is very exciting as we have given the robot under our supervision - the ability to design the experiments and interpret the data for us," says Professor Ross King from the University of Wales, Aberystwyth. "There is increasing need for automation in the biological sciences and, although the problems we set for the robot were relatively simple, we have shown that it could be used to help solve real-world problems."

The researchers set the robot the problem of discovering the function of different genes in baker's yeast (Saccharomyces cerevisiae). The functions of about 30% of the 6,000 genes in yeast are still unknown and, with many of these genes thought to be common to the human genome, they could prove to be medically important in the future. The research involved using "knockout" strains of yeast that have had one gene removed. By observing how the yeast grows, or doesn't grow, on defined chemical substrates, it is possible to start establishing different possible functions for the gene being investigated. "This is like trying to understand what the different components in a car do by removing them one by one, " says Professor King.

The robot scientist generates a set of hypotheses from what it knows about biochemistry and then plans an experiment that will eliminate as many hypotheses as possible, as fast and as cheaply as possible. It conducts experiments by dispensing and mixing liquids and then measuring the growth of yeast using an adjacent plate reader that feeds the results back into the system. The robot then evaluates the results against the set of hypotheses, generates new hypotheses, and the process starts again
'"/>

Contact: Professor Ross King, University of Wales, Aberystwyth
rdk@aber.ac.uk
44-197-062-2432
Biotechnology and Biological Sciences Research Council
14-Jan-2004


Page: 1 2

Related biology news :

1. Worlds largest scientific society convenes regional meeting June 2-4 in Indianapolis
2. Worlds oldest modern hummingbirds described in Science
3. Worlds oldest mouse celebrates milestone birthday
4. Worlds largest tiger reserve declared in Myanmar
5. Worlds first databank for all living systems
6. Worlds largest-ever sea turtle symposium to address plummeting populations of sea turtles
7. Worlds leading mad cow diagnostic company, responds to USDAs additional BSE protection measures
8. Worlds largest scientific society holds regional meeting in Columbia, Mo.
9. Worlds most alkaline life forms found near Chicago
10. Worlds largest forest birds may produce worlds deepest bird calls
11. Worlds largest scientific society holds regional meeting in Long Beach, Calif.

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/22/2020)... , ... July 21, 2020 , ... ... transformation and innovation in technology and compliance, announces a new solution to manage ... must ensure every layer of their technology stack complies with FDA and global ...
(Date:7/18/2020)... ... ... Commercial launch readiness is a critical stage in a product life cycle. While ... global economic downturn will only increase price pressures overall for the industry. The era ... from every product launch is critical. However, history shows that only a third of ...
(Date:7/10/2020)... ... July 09, 2020 , ... Today CJ BIO announced the first in ... on the “fifth taste” phenomenon that is revolutionizing ingredient mixes, nutritional content and flavor ... live on Monday, July 13, 2020 at11:00 AM (CDT) during SHIFT20, the virtual edition ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... , ... July 29, 2020 , ... ... of the top radiation centers in 16 countries, has reached its 20th anniversary ... is now in routine use at top universities including University of Pennsylvania, University ...
(Date:7/18/2020)... ... 16, 2020 , ... “We are thrilled to deliver this new technology to ... of its kind on the market and we were pleased that the IFT jury ... traditional cultured ingredients, creating a natural way to extend the shelf life and improve ...
(Date:7/10/2020)... , ... July 09, 2020 ... ... company, announced today that Massachusetts Institute of Technology (MIT) has expanded the ... license allows PathSensors to move into the point-of-care diagnostic market, focusing initially ...
(Date:7/7/2020)... ... July 06, 2020 , ... Bio-IT World has announced the ... Squibb, the University of Chicago, Massachusetts General Hospital, Mission: Cure, and the Pistoia ... program, highlighting outstanding examples of how technology innovations and strategic initiatives can be ...
Breaking Biology Technology:
Cached News: