HOME >> BIOLOGY >> NEWS
World's oldest mouse celebrates milestone birthday

ANN ARBOR, Mich. Yoda, the world's oldest mouse, celebrated his fourth birthday on Saturday, April 10, 2004. A dwarf mouse, Yoda lives in quiet seclusion with his cage mate, Princess Leia, in a pathogen-free rest home for geriatric mice belonging to Richard A. Miller, M.D., Ph.D., a professor of pathology in the Geriatrics Center of the University of Michigan Medical School.

Yoda was born on April 10, 2000 at the U-M Medical School. At 1,462-days-old, Yoda is now the equivalent of about 136 in human-years. The life span of the average laboratory mouse is slightly over two years.

"Yoda is only the second mouse I know to have made it to his fourth birthday without the rigors of a severe calorie-restricted diet," Miller says. "He's the oldest mouse we've seen in 14 years of research on aged mice at U-M. The previous record-holder in our colony died nine days short of his fourth birthday. 100-year-old people are much more common than four-year-old mice."

Miller is an expert on the genetics and cell biology of aging. To study the aging process, he has developed strains of mice, derived from wild mice captured in Idaho, that live longer, stay smaller and age more slowly than ordinary mice. Although extremely low-calorie diets have been shown by other scientists to produce very long-lived mice, the genetic approaches used in Miller's laboratory achieve longevity without the need to restrict food intake.

Miller's mouse colony also includes strains of mutant dwarf mice, developed at Jackson Laboratories, which are very small and long-lived. Yoda is the longest-living member of this unusual tribe.

Miller's geriatric mice are providing important clues about how genes and hormones affect the rate of human aging and risks of disease late in life. His current work focuses on identifying defects in T cells from aged mice that interfere with a normal immune response, and finding ways to reverse those defects.


'"/>

Contact: Sally Pobojewski
pobo@umich.edu
734-615-6912
University of Michigan Health System
12-Apr-2004


Page: 1

Related biology news :

1. Worlds largest scientific society convenes regional meeting June 2-4 in Indianapolis
2. Worlds oldest modern hummingbirds described in Science
3. Worlds largest tiger reserve declared in Myanmar
4. Worlds first databank for all living systems
5. Worlds largest-ever sea turtle symposium to address plummeting populations of sea turtles
6. Worlds first robot scientist proves a major success in the lab
7. Worlds leading mad cow diagnostic company, responds to USDAs additional BSE protection measures
8. Worlds largest scientific society holds regional meeting in Columbia, Mo.
9. Worlds most alkaline life forms found near Chicago
10. Worlds largest forest birds may produce worlds deepest bird calls
11. Worlds largest scientific society holds regional meeting in Long Beach, Calif.

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: World oldest mouse celebrates milestone birthday

(Date:4/16/2014)... Sometimes known as Kennedy,s disease, spinal and bulbar muscular atrophy ... progressive muscle weakness and atrophy. Researchers have long considered it ... the cells in the spinal cord and brainstem that control ... the April 16, 2014 online issue of Neuron , ...
(Date:4/16/2014)... store memories improves during childhood, associated with structural changes ... parietal cortices. New research from UC Davis is exploring ... Eventually, that could give insights into disorders that typically ... affect memory, such as schizophrenia and depression. , Located ...
(Date:4/15/2014)... Ohio (April 16, 2014)A new study from the Women,s ... D levels and menopause symptoms. The study was published ... The North American Menopause Society., The authors analyzed the ... a number of menopause symptoms, including hot flashes, night ...
Breaking Biology News(10 mins):Mutant protein in muscle linked to neuromuscular disorder 2How kids' brain structures grow as memory develops 2Low Vitamin D may not be a culprit in menopause symptoms 2
(Date:1/15/2014)... Two champions of science, technology, engineering, and ... annual competition for middle and high school students designed ... study. The competition presents students with real-world problems experienced ... Mathematics, and Sciences is a program administered by ...
(Date:1/15/2014)... Freeslate, Inc ., the leading provider of ... one of India’s top five pharmaceutical companies, has received ... for high throughput solid form screening. , Lupin, ... range of quality, affordable generic and branded formulations and ...
(Date:1/14/2014)... Carahsoft and CDS Federal Services have ... at 2pm EST (11am PST), “Natural Language Processing: Converting ... how technology can turn raw, heterogeneous data into actionable ... The online webinar will last approximately one hour. , ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 EquitiesIQ, a ... Inc. (OTCQB: ALQA). Alliqua is an emerging biomedical company ... the wound care market. , Free report download: ... with a seasoned management team and Board, which launched ...
Breaking Biology Technology:Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
Cached News: