HOME >> BIOLOGY >> NEWS
World's oldest mouse celebrates milestone birthday

ANN ARBOR, Mich. Yoda, the world's oldest mouse, celebrated his fourth birthday on Saturday, April 10, 2004. A dwarf mouse, Yoda lives in quiet seclusion with his cage mate, Princess Leia, in a pathogen-free rest home for geriatric mice belonging to Richard A. Miller, M.D., Ph.D., a professor of pathology in the Geriatrics Center of the University of Michigan Medical School.

Yoda was born on April 10, 2000 at the U-M Medical School. At 1,462-days-old, Yoda is now the equivalent of about 136 in human-years. The life span of the average laboratory mouse is slightly over two years.

"Yoda is only the second mouse I know to have made it to his fourth birthday without the rigors of a severe calorie-restricted diet," Miller says. "He's the oldest mouse we've seen in 14 years of research on aged mice at U-M. The previous record-holder in our colony died nine days short of his fourth birthday. 100-year-old people are much more common than four-year-old mice."

Miller is an expert on the genetics and cell biology of aging. To study the aging process, he has developed strains of mice, derived from wild mice captured in Idaho, that live longer, stay smaller and age more slowly than ordinary mice. Although extremely low-calorie diets have been shown by other scientists to produce very long-lived mice, the genetic approaches used in Miller's laboratory achieve longevity without the need to restrict food intake.

Miller's mouse colony also includes strains of mutant dwarf mice, developed at Jackson Laboratories, which are very small and long-lived. Yoda is the longest-living member of this unusual tribe.

Miller's geriatric mice are providing important clues about how genes and hormones affect the rate of human aging and risks of disease late in life. His current work focuses on identifying defects in T cells from aged mice that interfere with a normal immune response, and finding ways to reverse those defects.


'"/>

Contact: Sally Pobojewski
pobo@umich.edu
734-615-6912
University of Michigan Health System
12-Apr-2004


Page: 1

Related biology news :

1. Worlds largest scientific society convenes regional meeting June 2-4 in Indianapolis
2. Worlds oldest modern hummingbirds described in Science
3. Worlds largest tiger reserve declared in Myanmar
4. Worlds first databank for all living systems
5. Worlds largest-ever sea turtle symposium to address plummeting populations of sea turtles
6. Worlds first robot scientist proves a major success in the lab
7. Worlds leading mad cow diagnostic company, responds to USDAs additional BSE protection measures
8. Worlds largest scientific society holds regional meeting in Columbia, Mo.
9. Worlds most alkaline life forms found near Chicago
10. Worlds largest forest birds may produce worlds deepest bird calls
11. Worlds largest scientific society holds regional meeting in Long Beach, Calif.

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: World oldest mouse celebrates milestone birthday

(Date:10/22/2014)... identity analyst firm Acuity Market Intelligence forecasts that in ... have a chip-based National eID card, including near-complete regional ... Asia , with its vast population, is expected ... of all National eID cards issued between 2014 and ... National eID Industry Report: 2014 Edition" — projects ...
(Date:10/18/2014)... a group of 2,000 patients referred for evaluation ... potential molecular diagnosis for 25 percent, including detection ... new mutations contributing to disease, according to a ... is being released to coincide with the American ... sequencing analyzes the exons or coding regions of ...
(Date:10/17/2014)... for the first time how bacteria can grow directly ... the opportunity to get tremendous insights into bacteria behavior ... discovered the bacterial growth in chronic lung infections among ... by the immune cells. The researchers discovered the immune ... bacteria, forcing the bacteria to switch to a much ...
Breaking Biology News(10 mins):Half the World's Population Will Have Chip-Based National Electronic Identity (eID) Cards by 2018 2Whole-exome sequencing shows potential as diagnostic tool 2Scientists opens black box on bacterial growth in cystic fibrosis lung infection 2
(Date:10/22/2014)... Oct. 22, 2014 Research and ... "Global DNA Diagnostics Market (Product types, Application, ... Global Trends, Company Profiles, Demand, Insights, Analysis, Research, ... report to their offering. ... applications, techniques, end users and Geography) Global Size, ...
(Date:10/22/2014)... October 22, 2014 Involution Studios ... release of a new infographic, Understanding Ebola . ... a beautifully designed, easy to follow informative tool for ... of outbreak, symptoms and prevention. , "As the news ... the 2014 Ebola outbreak represents not only a healthcare ...
(Date:10/22/2014)... According to new market research ... (Consulting, Integration, Deployment & Support), by Service Model ... Private, Others (Hybrid & Community)) - Global Forecast ... the Cloud Professional Services Market into various sub-segments ... It also identifies the drivers and restraints for ...
(Date:10/22/2014)... KONG , Oct. 22, 2014  aTyr Pharma ... that rare disease expert John C. McKew , ... McKew brings more than two decades of expertise in ... Institutes of Health, Wyeth Research and Genetics Institute, Inc. ... aTyr,s efforts to expand and translate its novel Physiocrine ...
Breaking Biology Technology:Global DNA Diagnostics Market (Product types, Application, Technology, End User and Geography) - Forecast to 2020 2Global DNA Diagnostics Market (Product types, Application, Technology, End User and Geography) - Forecast to 2020 3Involution Studios' Ebola Infographic Provides Key Disease Information and Statistics at a Glance 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 3Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 4Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 5aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 2aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 3
Cached News: