HOME >> BIOLOGY >> NEWS
World's oldest mouse celebrates milestone birthday

ANN ARBOR, Mich. Yoda, the world's oldest mouse, celebrated his fourth birthday on Saturday, April 10, 2004. A dwarf mouse, Yoda lives in quiet seclusion with his cage mate, Princess Leia, in a pathogen-free rest home for geriatric mice belonging to Richard A. Miller, M.D., Ph.D., a professor of pathology in the Geriatrics Center of the University of Michigan Medical School.

Yoda was born on April 10, 2000 at the U-M Medical School. At 1,462-days-old, Yoda is now the equivalent of about 136 in human-years. The life span of the average laboratory mouse is slightly over two years.

"Yoda is only the second mouse I know to have made it to his fourth birthday without the rigors of a severe calorie-restricted diet," Miller says. "He's the oldest mouse we've seen in 14 years of research on aged mice at U-M. The previous record-holder in our colony died nine days short of his fourth birthday. 100-year-old people are much more common than four-year-old mice."

Miller is an expert on the genetics and cell biology of aging. To study the aging process, he has developed strains of mice, derived from wild mice captured in Idaho, that live longer, stay smaller and age more slowly than ordinary mice. Although extremely low-calorie diets have been shown by other scientists to produce very long-lived mice, the genetic approaches used in Miller's laboratory achieve longevity without the need to restrict food intake.

Miller's mouse colony also includes strains of mutant dwarf mice, developed at Jackson Laboratories, which are very small and long-lived. Yoda is the longest-living member of this unusual tribe.

Miller's geriatric mice are providing important clues about how genes and hormones affect the rate of human aging and risks of disease late in life. His current work focuses on identifying defects in T cells from aged mice that interfere with a normal immune response, and finding ways to reverse those defects.


'"/>

Contact: Sally Pobojewski
pobo@umich.edu
734-615-6912
University of Michigan Health System
12-Apr-2004


Page: 1

Related biology news :

1. Worlds largest scientific society convenes regional meeting June 2-4 in Indianapolis
2. Worlds oldest modern hummingbirds described in Science
3. Worlds largest tiger reserve declared in Myanmar
4. Worlds first databank for all living systems
5. Worlds largest-ever sea turtle symposium to address plummeting populations of sea turtles
6. Worlds first robot scientist proves a major success in the lab
7. Worlds leading mad cow diagnostic company, responds to USDAs additional BSE protection measures
8. Worlds largest scientific society holds regional meeting in Columbia, Mo.
9. Worlds most alkaline life forms found near Chicago
10. Worlds largest forest birds may produce worlds deepest bird calls
11. Worlds largest scientific society holds regional meeting in Long Beach, Calif.

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/3/2018)... , ... November 01, 2018 , ... ... the morphology, physiology and pathology of the human dental pulp and periradicular tissues. ... of the human teeth, but, over the last decade, non-destructive, high-resolution micro-CT 3D ...
(Date:10/31/2018)... ... October 31, 2018 , ... RPS Diagnostics, ... the way for its immediate launch in the European Union and all countries ... point-of-care test that is expected to contribute towards a diagnostic solution to the ...
(Date:10/26/2018)... ... ... uBiome, the leader in microbial genomics, announces the addition of Dr. Jonathan ... of California Los Angeles (UCLA), to its Scientific Advisory Board. Joining the board of ... a deep expertise on the role of the immune system in resistance and susceptibility ...
Breaking Biology News(10 mins):
(Date:11/9/2018)... ... November 08, 2018 , ... uBiome, the leader in microbial ... and President of Andes Biotechnologies, to its Scientific Advisory Board. Joining the board ... uBiome expertise on the genetic studies of hepatitis viruses. The appointment will help ...
(Date:11/7/2018)... Mass. (PRWEB) , ... November 07, 2018 , ... ... system for algae at AzCATI, the Arizona Center for Algae Technology and Innovation at ... facilitate process development and trials for those involved with algal and predator control applications. ...
(Date:11/5/2018)... ... 05, 2018 , ... GlycoMark, Inc., the exclusive provider of ... website, http://www.glycomark.com , as part of National Diabetes Month. The new ... website in November from 9 a.m. – 5 p.m. ET weekdays for healthcare ...
(Date:10/31/2018)... ... ... Rooam , the premier payment platform for the nightlife and hospitality industry, announced ... Tally payment app, the leading payment platform in Chicago that allows users to track ... and increase the number of restaurant and bar locations offered on its payment platform. ...
Breaking Biology Technology:
Cached News: