HOME >> BIOLOGY >> NEWS
Yale professor receives Johnson & Johnson Focused Giving award

New Haven, Conn. -- Sidney Altman, Sterling Professor of Molecular, Cellular and Developmental Biology at Yale University has been awarded a three-year, Focused Giving Grant by Johnson & Johnson to support his work on coordinated regulation of the protein subunits of RNase P in HeLa Cells.

Professor Altman received the Nobel Prize for chemistry in 1989 for his work on RNaseP demonstrating that RNA as well as protein can have catalytic properties. The RNaseP enzyme in mammals contains at least 10 protein subunits in addition to the RNA subunit.

With this grant Altman's group will pursue the basis of their observation that directly inhibiting expression of one of the protein subunits (Rpp38) in human nuclear RNase P turned off the expression of some, but not all, subunits without further cell manipulation.

The research will use external guide sequences (EGS), RNA sequences that bind to the target RNA so that the complex looks like a normal substrate for RNase P, to identify and inactivate messages for the protein subunits. The presence of the EGS in cells subsequently works rapidly and specifically and has been used in the past to target essential virus genes and decrease infection. Understanding how to affect the expression of multiple genes in a coordinated manner has important implications for many basic biological functions, and disease treatments.


'"/>

Contact: Janet Rettig Emanuel
janet.emanuel@yale.edu
203-432-2157
Yale University
7-Jun-2004


Page: 1

Related biology news :

1. NJIT professor receives Presidential Award for breakthrough research with adult stem cells
2. Virginia Tech professor honored with DeLaval Award
3. New and better drugs for tuberculosis goal of UH professor
4. UCSB professor and director receives two national awards
5. K-State professor combines love of teaching, research to examine eye development
6. LSU vet school professor uses gene therapy to destroy cancerous tumors
7. COPD is forgotten killer, says University of Toronto professor
8. UC Riverside professor to spend year with US State Department
9. UGA professor Jeffrey Bennetzen named to National Academy of Sciences
10. Four IU professors are 2004 Guggenheim Fellows
11. Ohio State wetlands professor wins prestigious Water Prize

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: