HOME >> BIOLOGY >> NEWS
Yale researchers develop first microarray chip for complete analysis of proteins

Yale University researcher Michael Snyder and his colleagues have created the first microchip able to analyze virtually all yeast proteins, the chemicals that carry out the activities necessary for life.

The new protein chip holds promise for significant advances in the study of the function of proteins in other organisms beside yeast, including humans. "Most development occurs through the interactions among proteins," said Snyder, professor and chair of the Yale Department of Molecular, Cellular and Developmental Biology. "Diseases can arise when proteins do not interact properly. This technology allows us to get at the function of many of the different proteins far faster than current methods. This is opening up whole new areas that have never been approached before."

Besides increasing knowledge about how proteins function, the new protein chips could speed the development of new diagnostic methods, advancements in drug discovery, and improvements in therapies for diseases.

Announcement of the development of the new protein chip came in the July 26 online version of the journal Science and appeared in an article published in the September 14 issue.

Development of the new protein chip was based on previous knowledge of the identity of all 6,200 genes in a yeast cell. Each gene encodes for a protein, which interacts with other proteins to develop and sustain cell life. Prior to the Yale scientists' discovery, studying proteins on a large, nearly complete scale had never been done, and many scientists believed it was not possible.

Snyder, who is also co-director of the recently announced Yale Center of Excellence in Biomedical Computing, directed the study, which involved the collaboration of Heng Zhu, a post-doctoral fellow in his laboratory, and other Yale colleagues, along with investigators from North Carolina State University. They cloned and purified 5,800 different yeast proteins, representing 80 percent of the
'"/>

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University
31-Oct-2001


Page: 1 2

Related biology news :

1. Belgian researchers explore revolutionary approach to angiogenesis
2. Award winning researchers reveal potential new role for Glivec
3. $7.5 Million grant to Yale researchers for role of viruses in cancer
4. New anti-inflammatory strategy for cancer therapy identified by UCSD researchers
5. Joslin researchers clarify mechanisms for beta-cell formation
6. Virginia Tech researchers to release findings on Smith River Project
7. Molecular motor myosin VI moves hand over hand, researchers say
8. ASU researchers demonstrate new technique that improves the power of atomic force micrscopy
9. Emory researchers map structure of anti-cancer molecule
10. Leukemia stem cells identified by Stanford researchers
11. EURYI Award given for the first time to 25 young European researchers

Post Your Comments:
(Date:8/21/2014)... , Aug. 21, 2014 /PRNewswire-iReach/ -- ... it has agreed to a partnership with Gabriel ... fastest growing Certified Nursing Assistant ... Health Institute  an exclusive member of Binary,s LiveScan ... Binary Biometrics will improve its service capabilities ...
(Date:8/21/2014)... Nine researchers from Beth Israel Deaconess Medical ... "The World,s Most Influential Scientific Minds 2014," ... Reuters ScienceWatch, a web resource for science metrics and ... as among the most influential "are performing and publishing ... advancement of their science," according to a Thomson Reuters ...
(Date:8/21/2014)... Mller the Fram Strait is a key region in the ... between Greenland and Svalbard warm Atlantic water flows to the ... cold Arctic water masses and sea ice push their way ... portion of the Atlantic water cools here on its way ... of the water caused in this manner drives the global ...
Breaking Biology News(10 mins):LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 2LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 3BIDMC researchers named among 'the most influential scientific minds' 2BIDMC researchers named among 'the most influential scientific minds' 3Arctic sea ice influenced force of the Gulf Stream 2Arctic sea ice influenced force of the Gulf Stream 3
(Date:8/22/2014)... The identification of protein-coding variants underlying ... by exome sequencing. Built on Roche NimbleGen’s proprietary ... EZ Developer system has been a proven tool ... present how he achieved coverage statistics similar to ... exome kits. With over 236,000 SNPs and over ...
(Date:8/21/2014)... 21, 2014  BioSpecifics Technologies Corp. (NASDAQ: ... in class collagenase-based products marketed as XIAFLEX ® ... U.S. and XIAPEX ® in the EU, ... randomized, double-blind Phase 2a study of CCH for ... panniculopathy. The results showed that all three doses ...
(Date:8/21/2014)... at the Institute for Molecular Medicine Finland (FIMM), ... developed a novel "man and machine" decision support ... aid was described in PLOS One ... based on computer vision algorithms similar to those ... of only the diagnostically most relevant areas. Tablet ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 ... Fertilizer Industry” is a professional and in-depth ... The report provides basic Seaweed Fertilizer information, ... industry chain structure as well as industry ... analysis, including domestic market as well as ...
Breaking Biology Technology:Efficient Identification of Protein-Coding Variants in a Model Organism Through Exome Sequencing, New Webinar Hosted by Xtalks 2BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 2BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 3BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 4BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 5A novel 'man and machine' decision support system makes malaria diagnostics more effective 2Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 2Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 3
Cached News: