HOME >> BIOLOGY >> NEWS
Yale researchers develop first microarray chip for complete analysis of proteins

Yale University researcher Michael Snyder and his colleagues have created the first microchip able to analyze virtually all yeast proteins, the chemicals that carry out the activities necessary for life.

The new protein chip holds promise for significant advances in the study of the function of proteins in other organisms beside yeast, including humans. "Most development occurs through the interactions among proteins," said Snyder, professor and chair of the Yale Department of Molecular, Cellular and Developmental Biology. "Diseases can arise when proteins do not interact properly. This technology allows us to get at the function of many of the different proteins far faster than current methods. This is opening up whole new areas that have never been approached before."

Besides increasing knowledge about how proteins function, the new protein chips could speed the development of new diagnostic methods, advancements in drug discovery, and improvements in therapies for diseases.

Announcement of the development of the new protein chip came in the July 26 online version of the journal Science and appeared in an article published in the September 14 issue.

Development of the new protein chip was based on previous knowledge of the identity of all 6,200 genes in a yeast cell. Each gene encodes for a protein, which interacts with other proteins to develop and sustain cell life. Prior to the Yale scientists' discovery, studying proteins on a large, nearly complete scale had never been done, and many scientists believed it was not possible.

Snyder, who is also co-director of the recently announced Yale Center of Excellence in Biomedical Computing, directed the study, which involved the collaboration of Heng Zhu, a post-doctoral fellow in his laboratory, and other Yale colleagues, along with investigators from North Carolina State University. They cloned and purified 5,800 different yeast proteins, representing 80 percent of the
'"/>

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University
31-Oct-2001


Page: 1 2

Related biology news :

1. Belgian researchers explore revolutionary approach to angiogenesis
2. Award winning researchers reveal potential new role for Glivec
3. $7.5 Million grant to Yale researchers for role of viruses in cancer
4. New anti-inflammatory strategy for cancer therapy identified by UCSD researchers
5. Joslin researchers clarify mechanisms for beta-cell formation
6. Virginia Tech researchers to release findings on Smith River Project
7. Molecular motor myosin VI moves hand over hand, researchers say
8. ASU researchers demonstrate new technique that improves the power of atomic force micrscopy
9. Emory researchers map structure of anti-cancer molecule
10. Leukemia stem cells identified by Stanford researchers
11. EURYI Award given for the first time to 25 young European researchers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2016)... BANGALORE, India , April 28, 2016 ... subsidiary of Infosys (NYSE: INFY ), and Samsung ... global partnership that will provide end customers with a ... and payment services.      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ... for financial services, but it also plays a fundamental part ...
(Date:4/26/2016)... BANGALORE, India and LONDON ... Infosys Finacle, part of EdgeVerve Systems, a ... ), and Onegini today announced a partnership to ... banking solutions.      (Logo: http://photos.prnewswire.com/prnh/20151104/283829LOGO ... banks to provide their customers enhanced security to ...
(Date:4/19/2016)... April 20, 2016 The new ... a compact web-based "all-in-one" system solution for all door ... reader or the door interface with integration authorization management ... control systems. The minimal dimensions of the access control ... the building installations offer considerable freedom of design with ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... ... June 24, 2016 , ... Researchers at the Universita ... miRNAs in people with peritoneal or pleural mesothelioma. Their findings are the subject of ... now. , Diagnostic biomarkers are signposts in the blood, lung fluid or tissue ...
(Date:6/23/2016)... 23, 2016   Boston Biomedical , an ... designed to target cancer stemness pathways, announced that ... Orphan Drug Designation from the U.S. Food and ... cancer, including gastroesophageal junction (GEJ) cancer. Napabucasin is ... inhibit cancer stemness pathways by targeting STAT3, and ...
(Date:6/23/2016)... Houston Methodist Willowbrook Hospital has signed ... to serve as their official health care provider. ... will provide sponsorship support, athletic training services, and ... volunteers, athletes and families. "We are ... and to bring Houston Methodist quality services and ...
(Date:6/23/2016)... YORK , June, 23, 2016  The Biodesign ... to envision new ways to harness living systems and ... Modern Art (MoMA) in New York City ... than 130 participating students, showcased projects at MoMA,s Celeste ... Paola Antonelli , MoMA,s senior curator of architecture ...
Breaking Biology Technology:
Cached News: