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Yeast Rises To A New Occasion

ablishing this group, as well as for carrying out this important project, on a self-made gene-cloning technologist, a woman scientist, and a Purdue graduate who for family reasons had never left Purdue after receiving her Ph.D."

Geneticist Zhengdao Chen and technician Adam Brainard, members of Ho's research group, also contributed to the development of the yeast.

In 1993, Amoco Corp. licensed the yeast strain. SWAN Biomass Co., a subsidiary of Amoco, was established to develop the yeast for commercial applications. The company tested the yeast in a large-scale testing facility at the National Renewable Energy Laboratory in Golden, Colo. The results confirmed that the yeast is effective at co-fermenting glucose and xylose from cellulosic biomass into ethanol, Ho says.

Robert Walker, president of SWAN Biomass Co., says, "The first commercial applications of this new technology are likely to be in the production of fuel ethanol from field wastes generated on farms or from wastes that result as crops are processed for sale."

Ho says the next step is to further improve the yeast. "We anticipate that our final engineered yeast strain may require only half the time to co-ferment the same amount of glucose and xylose as the current strain," Ho says. In addition, she says the new method they developed to integrate multiple copies of genes into the yeast chromosome could be used to make yeast capable of producing other high-value byproducts in addition to ethanol.

Ho's research has been funded by the Department of Energy through the Consortium for Plant Biotechnology Research Inc.; the U.S. Environmental Protection Agency; and industry, including SWAN Biomass. aas/9808 SP Ho.yeast/9807f28 Sources: Nancy Ho, (765) 494-7046; e-mail, nwyho@ecn.purdue.edu Robert Walker, SWAN Biomass Co., (630) 889-7126 Writer:
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Contact: Amanda Siegfried
amanda_siegfried@uns.purdue.edu
765-494-4709
Purdue University
20-Aug-1998


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