HOME >> BIOLOGY >> NEWS
Zebrafish's powerful heart gene could lead to transplant therapy

receives blood and passes it to the ventricles) and the ventricle (the pumping chamber). This work will allow the researchers to formulate specific hypotheses regarding the various cell interactions and molecules involved in these processes. The finding was reported in Developmental Biology.

With potential therapeutic implications, Stainier and a colleague also recently discovered that endothelial cells, which line the blood vessels, play a critical role in inducing the development, or proper differentiation, of red blood cells, the transporters of oxygen. When endothelial cells were removed from the developing zebrafish embryo, red blood cells did not form. When endothelial cells were restored, blood cells developed. (The researchers were able to conduct this experiment because the embryos can survive without blood for at least seven days.). Presumably, said Stainier, the endothelial cells act by releasing an as-yet-unidentified factor.

The finding represents the first demonstration in an animal model, Stainier said, that endothelial cells are necessary for the proper differentiation of red blood cells. He said he suspects the discovery, published in Development,5 will apply to the immune system's white blood cells, as well.

Identifying the factor released by endothelial cells could lead, said Stainier, to a mechanism for prompting naive, or undifferentiated, cells to develop into red blood cells, which could then be used to boost the blood supply. "The insights zebrafish can offer into human biology and medicine are boundless," said Stainier. "We will be learning from these animals for years to come."

http://pubaffr.ucsf.edu/imagedb/imsearch.php3?keywords=zebrafish


'"/>

Contact: Jennifer O'Brien
jobrien@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
8-Dec-1999


Page: 1 2 3 4 5 6

Related biology news :

1. FDA approves VYTORIN, first and only to powerfully reduce LDL cholesterol through dual inhibition
2. Spanish scientists develop powerful tool for exploration and integration of biological information
3. Volcanic soils yield new clues about the emergence of powerful chiefdoms in Hawaii
4. Fruits offer powerful protection from skin cancer
5. Grant of powerful computer to Rutgers-Newark will increase understanding of brain activity
6. Hopkins is first US institution to obtain powerful genotyping system
7. Atomic force microscope powerful new tool for measurement of particle attraction
8. Brain banks are a powerful tool for alcohol research
9. UCSD brings powerful visualization to high school classroom
10. Scientists harness powerful x-rays in new technique to study animal functions
11. Black raspberries a potentially powerful agent in fight against colon cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/13/2016)... , January 13, 2016 ... published a new market report titled - Biometric Sensors Market ... Forecast, 2015 - 2023. According to the report, the global biometric ... is anticipated to reach US$1,625.8 mn by 2023, expanding ... In terms of volume, the biometric sensors market is ...
(Date:1/11/2016)... 11, 2016 Synaptics Incorporated (NASDAQ: SYNA ... announced that its ClearPad ® TouchView ™ ... two separate categories in the 8 th Annual ... Technology Breakthrough. The Synaptics ® TDDI solution enables ... chain, thinner devices, brighter displays and borderless designs. ...
(Date:1/8/2016)... and MANCHESTER, United Kingdom , ... a developer of innovative sensor-based diagnostic products, today announced the ... by new and existing investors.  Proceeds from the financing will ... Scanner , a hand-held device for detecting early-stage pressure ulcers. ... Ireland after receiving CE Mark approval. The ...
Breaking Biology News(10 mins):
(Date:2/8/2016)... ... February 08, 2016 , ... Thomas J. Todorow has joined ... President for Corporate Services and the Chief Financial Officer at The Children’s Hospital ... Treasury, Managed Care Contracting, Supply Chain, and Investments. , Prior to joining CHOP ...
(Date:2/8/2016)... ... February 08, 2016 , ... Franz Inc. , an ... technology, today announced the availability of AllegroGraph 6, the leading Semantic Graph Database ... Certified Technology Program (CCPT). AllegroGraph is the first Semantic Graph Database to ...
(Date:2/8/2016)... 2016 --> ... "Company"), the ultra-rapid Point-Of-Care (POC) molecular diagnostics company, today announces ... trachomatis (CT) test to be launched on the Company,s io® ... the CT test is now cleared for sale within the ... The launch of the io® CT test signals a new ...
(Date:2/5/2016)... , Feb. 5, 2016  In the pharmaceutical ... for a host of launch activities including the identification ... this launch activity is especially high in the oncology ... Best Practices and the Role of Medical Affairs ... companies focused on oncology therapies find better ways to ...
Breaking Biology Technology:
Cached News: