HOME >> BIOLOGY >> NEWS
Zebrafish's powerful heart gene could lead to transplant therapy

receives blood and passes it to the ventricles) and the ventricle (the pumping chamber). This work will allow the researchers to formulate specific hypotheses regarding the various cell interactions and molecules involved in these processes. The finding was reported in Developmental Biology.

With potential therapeutic implications, Stainier and a colleague also recently discovered that endothelial cells, which line the blood vessels, play a critical role in inducing the development, or proper differentiation, of red blood cells, the transporters of oxygen. When endothelial cells were removed from the developing zebrafish embryo, red blood cells did not form. When endothelial cells were restored, blood cells developed. (The researchers were able to conduct this experiment because the embryos can survive without blood for at least seven days.). Presumably, said Stainier, the endothelial cells act by releasing an as-yet-unidentified factor.

The finding represents the first demonstration in an animal model, Stainier said, that endothelial cells are necessary for the proper differentiation of red blood cells. He said he suspects the discovery, published in Development,5 will apply to the immune system's white blood cells, as well.

Identifying the factor released by endothelial cells could lead, said Stainier, to a mechanism for prompting naive, or undifferentiated, cells to develop into red blood cells, which could then be used to boost the blood supply. "The insights zebrafish can offer into human biology and medicine are boundless," said Stainier. "We will be learning from these animals for years to come."

http://pubaffr.ucsf.edu/imagedb/imsearch.php3?keywords=zebrafish


'"/>

Contact: Jennifer O'Brien
jobrien@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
8-Dec-1999


Page: 1 2 3 4 5 6

Related biology news :

1. FDA approves VYTORIN, first and only to powerfully reduce LDL cholesterol through dual inhibition
2. Spanish scientists develop powerful tool for exploration and integration of biological information
3. Volcanic soils yield new clues about the emergence of powerful chiefdoms in Hawaii
4. Fruits offer powerful protection from skin cancer
5. Grant of powerful computer to Rutgers-Newark will increase understanding of brain activity
6. Hopkins is first US institution to obtain powerful genotyping system
7. Atomic force microscope powerful new tool for measurement of particle attraction
8. Brain banks are a powerful tool for alcohol research
9. UCSD brings powerful visualization to high school classroom
10. Scientists harness powerful x-rays in new technique to study animal functions
11. Black raspberries a potentially powerful agent in fight against colon cancer

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Zebrafish powerful heart gene could lead transplant therapy

(Date:10/22/2014)... 2014  Leading identity analyst firm Acuity Market Intelligence ... world,s population will have a chip-based National eID card, ... . Asia , with its vast ... more than 60% of all National eID cards issued ... "The Global National eID Industry Report: 2014 ...
(Date:10/19/2014)... in India over the last 30 years contributed ... growth during that time, according to a new ... Change ., "Energy access is fundamental to development: ... including education, communication, and health," says IIASA researcher ... increased energy access is widely agreed to be ...
(Date:10/18/2014)... referred for evaluation of suspected genetic conditions, whole-exome ... percent, including detection of a number of rare ... according to a study appearing in JAMA ... with the American Society of Human Genetics annual ... coding regions of thousands of genes simultaneously using ...
Breaking Biology News(10 mins):Half the World's Population Will Have Chip-Based National Electronic Identity (eID) Cards by 2018 2Improved electricity access has little impact on climate change 2Whole-exome sequencing shows potential as diagnostic tool 2
(Date:10/22/2014)... NJ (PRWEB) October 22, 2014 ... and services – has been working with a team ... and New Haven Farms Community Farming Collaborative to provide ... ePRO solution. The study, which started in May, ... program that provides participants weekly exposure to and participation ...
(Date:10/22/2014)... (PRWEB) October 22, 2014 Grace Century, ... and healthcare projects, announces the addition of Dr. ... to its advisory team. Dr. Siddiqui will provide further ... , A graduate of University College Medical School ... degreed in medicine in 2001. With further certification as ...
(Date:10/22/2014)... 22, 2014 According to new ... Service Type (Consulting, Integration, Deployment & Support), by ... Model (Public, Private, Others (Hybrid & Community)) - ... and segments the Cloud Professional Services Market into ... of revenues. It also identifies the drivers and ...
(Date:10/22/2014)... /PRNewswire/ - iCo Therapeutics ("iCo" or "the Company") (TSX-V: ... its Oral Amphotericin B program.  The company recently ... work involving samples from HIV/AIDS patients exposed ... pre clinical studies and regulatory filings to move ... utilizing approximately $700,000 of funding and technological advice ...
Breaking Biology Technology:myPROpad™ Topic of Panel Discussion at the Yale Food Systems Symposium 2myPROpad™ Topic of Panel Discussion at the Yale Food Systems Symposium 3Dr. Yousef Siddiqui joins the Grace Century Advisory Team 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 3Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 4Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 5iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 3
Cached News: