HOME >> BIOLOGY >> NEWS
Zebrafish's powerful heart gene could lead to transplant therapy

receives blood and passes it to the ventricles) and the ventricle (the pumping chamber). This work will allow the researchers to formulate specific hypotheses regarding the various cell interactions and molecules involved in these processes. The finding was reported in Developmental Biology.

With potential therapeutic implications, Stainier and a colleague also recently discovered that endothelial cells, which line the blood vessels, play a critical role in inducing the development, or proper differentiation, of red blood cells, the transporters of oxygen. When endothelial cells were removed from the developing zebrafish embryo, red blood cells did not form. When endothelial cells were restored, blood cells developed. (The researchers were able to conduct this experiment because the embryos can survive without blood for at least seven days.). Presumably, said Stainier, the endothelial cells act by releasing an as-yet-unidentified factor.

The finding represents the first demonstration in an animal model, Stainier said, that endothelial cells are necessary for the proper differentiation of red blood cells. He said he suspects the discovery, published in Development,5 will apply to the immune system's white blood cells, as well.

Identifying the factor released by endothelial cells could lead, said Stainier, to a mechanism for prompting naive, or undifferentiated, cells to develop into red blood cells, which could then be used to boost the blood supply. "The insights zebrafish can offer into human biology and medicine are boundless," said Stainier. "We will be learning from these animals for years to come."

http://pubaffr.ucsf.edu/imagedb/imsearch.php3?keywords=zebrafish


'"/>

Contact: Jennifer O'Brien
jobrien@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
8-Dec-1999


Page: 1 2 3 4 5 6

Related biology news :

1. FDA approves VYTORIN, first and only to powerfully reduce LDL cholesterol through dual inhibition
2. Spanish scientists develop powerful tool for exploration and integration of biological information
3. Volcanic soils yield new clues about the emergence of powerful chiefdoms in Hawaii
4. Fruits offer powerful protection from skin cancer
5. Grant of powerful computer to Rutgers-Newark will increase understanding of brain activity
6. Hopkins is first US institution to obtain powerful genotyping system
7. Atomic force microscope powerful new tool for measurement of particle attraction
8. Brain banks are a powerful tool for alcohol research
9. UCSD brings powerful visualization to high school classroom
10. Scientists harness powerful x-rays in new technique to study animal functions
11. Black raspberries a potentially powerful agent in fight against colon cancer

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Zebrafish powerful heart gene could lead transplant therapy

(Date:10/16/2014)... can be cultivated efficiently, they are anything but ... by monoculture cultivation is becoming increasingly evident. Despite ... form and are regarded as the sole possibility ... quite wrongfully, finds Bernhard Schmid, an ecology professor ... novel form of agriculture and forestry. After all, ...
(Date:10/15/2014)... our ability to assess the pandemic risk from strains ... we must not allow ourselves to become complacent that ... international consortium of scientists. , Influenza pandemics arise when ... yet to develop widespread immunity – spreads in the ... the past 100 years, the worst of which – ...
(Date:10/15/2014)... NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) ... growing mobile commerce market releases photos and video of the recent ... October 13 th . Gino Pereira , ... angel investor Mr. Chad A. Verdi rang the bell.  ... his investors and employees "for their work and dedication in bringing ...
Breaking Biology News(10 mins):Plant communities produce greater yield than monocultures 2Plant communities produce greater yield than monocultures 3Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3
(Date:10/20/2014)... 20, 2014 PureTech , a science ... healthcare problems, announced today the closing of a ... from Invesco Perpetual, a $120 Billion group of ... PureTech,s existing pipeline forward and to advance new ... scientific creativity to really go for the big ...
(Date:10/19/2014)... 2014 The Latin American hardware encryption ... Latin America with analysis and forecast of revenue. This ... is expected to reach $2,366.8 million by 2018, at ... Browse through the TOC of the Latin American hardware ... in-depth analysis provided. It also provides a glimpse of ...
(Date:10/19/2014)... The Asian Automatic patient billing report defines and ... of revenue. The Automatic patient billing market in Asia ... 2018, at a developing CAGR of 7.2% from 2013 ... Asian Automatic patient billing market, to get an idea ... glimpse of the segmentation of this market in the ...
(Date:10/19/2014)... 2014 The report "Unmanned Ground ... Security), Technology, Payload, Type & by Geography - ... global unmanned ground vehicle market into various sub ... market sizes. The report also identifies the factors ... it along with the adoption trends. , The ...
Breaking Biology Technology:PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 2The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 3The Asian Automatic patient billing market is estimated to grow to around $463.9 million by 2018 - New Report by MicroMarket Monitor 2The Asian Automatic patient billing market is estimated to grow to around $463.9 million by 2018 - New Report by MicroMarket Monitor 3Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 2Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 3Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 4Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 5
Cached News: