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$7.3 million NIH grant establishes Wellstone Muscular Dystrophy Research Center at the UI

over the principles governing the differentiation of these cells into muscle-forming precursor cells that can be used for cell transplantation therapies in mouse models of muscular dystrophies.

Core facility A, directed by Campbell, is an administrative core, which will coordinate and oversee the center's work.

Core B, directed by Moore and Rita Barresi, Ph.D., UI research associate, is a muscle tissue/cell culture/diagnostics core that will serve as a national tissue and cell culture resource for muscular dystrophy studies, provide diagnostic expertise for patients, and examine muscle biopsies from clinical trial participants to evaluate new treatments.

Core C, directed by Yang and Roger Williamson, M.D., UI professor of obstetrics and gynecology, will alter muscular dystrophy genes in embryonic stem cells, and coax the gene-targeted embryonic stem cells to become muscle tissue. The ultimate goal is to provide cell-based models of disease for development of therapies against the diverse forms of muscular dystrophy. The core will be a national resource of targeted stem cells.

University of Iowa Health Care describes the partnership between the UI Roy J. and Lucille A. Carver College of Medicine and UI Hospitals and Clinics and the patient care, medical education and research programs and services they provide. Visit UI Health Care online at http://www.uihealthcare.com.


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Contact: Jennifer Brown
jennifer-l-brown@uiowa.edu
319-335-9917
University of Iowa
1-Jul-2005


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