Full press releases on these presentations are available on the American Physiological Society website (http://www.the-aps.org/press/) or on EurekAlert. All abstracts may be accessed at http://www.faseb.org/meetings/eb2005/call/default.htm, through a searchable online program for both IUPS and Experimental Biology 2005.
Statins, other cholesterol depletors, may disrupt hypertension development: UCSD study
Cholesterol-lowering agents, such as statins, and cholesterol-blocking agents may prove to be novel therapeutic agents to modify cellular calcium that contributes to the development of pulmonary hypertension. The UCSD team found a previously unappreciated cellular and molecular mechanism for the disease process that may be amenable to treatment with current and future therapies and might provide more substantial, long-term benefit to those with hypertension.
"Cholesterol-depleting drugs, including statins, lower intracellular Ca2+ and inhibit proliferation in pulmonary artery smooth muscle cells in primary pulmonary hypertension." Physiology 933.6. Hemal H. Patel, Fiona Murray and Paul A. Insel, University of California, San Diego, Department of Pharmacology; Shen Zhang and Jason X-J Yuan, Dept. of Medicine, and Patricia A. Thistlethwaite, Dept. of Surgery.
Featured topic: Patel will participate in Session 898, "Overview: From organelles to organ," IUPS Calcium Signaling Track, Tuesday at 10:30 a.m., room 29C.
Cranberry juice modulates atherosclerotic vascular dysfunction
Taking cranberry juice powder regularly over six months saw a pronounced improvement in vascular function - ability of blood vessels to re