Pediatric burn victims' recovery, diabetes, metabolism aided by fenofibrate (Tricor)

Increasing cell fat metabolism with fenofibrate (Tricor) in seriously burned children also improved glucose metabolism to nearly normal levels, according to clinical work at University of Texas Medical Branch and Shriners Hospital for Children. With diabetes a common reaction to trauma and surgery, directly treating insulin resistance could speed recovery. The researchers found that a surprising 70% of victims 4 to 14 with over 40% surface burns suffered insulin sensitivity about half of healthy children.

"Fenofibrate improves glucose metabolism in pediatric burns patients." Physiology 361.2. Melanie Green Cree, Alse Aarsland, David Chinkes, David N. Herndon and Robert R. Wolfe from the University of Texas Medical Branch and Shriners Hospital for Children, Galveston.

Moderate aerobic exercise improves cardiovascular and nervous system function in HIV+

First study to demonstrate the profound effects of aerobic fitness on pre-clinical manifestations of cardiovascular and autonomic dysfunction in HIV was conducted at Teachers College/ Columbia University, and Coler Goldwater Specialty Hospital, New York. Moderate exercise was 10 weeks, 3 times a week, 45 minutes/session. Cardio-vascular and autonomic profiles of the fit HIV+ subjects were significantly improved compared to a similar group that didn't exercise -- regardless if they had HIV or not.

"Fitness is associated with improved arterial compliance and parasympathetic modulation in HIV," Physiology 347.11. David K. Spierer, Adrienne Zion, Gregory Gates and Ronald De Meersman, Dept. of Biobehavioral Sciences, Teachers Col
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4-Apr-2005