HOME >> BIOLOGY >> NEWS
454 Life Sciences and Max Planck publish sequence of one million base pairs

BRANFORD, Conn. November 15, 2006 CuraGen Corporation's (NASDAQ: CRGN) majority-owned subsidiary 454 Life Sciences today announced that comparison of the human and chimpanzee genomes to Neandertal DNA sequences determined by 454 SequencingTM reveals that modern human and Neandertal DNA sequences diverged on average about 500,000 years ago and the effective size of the ancestral population of the two groups was similar to that of modern humans. The publication is the impetus of the collaboration with the Max Planck Institute of Evolutionary Anthropology to sequence the complete Neandertal genome. The research, published online (ahead of print) in the journal Nature, is titled: "Analysis of one million base pairs of Neandertal DNA".

"Direct high-throughput 454 Sequencing of a DNA extract from a Neandertal fossil has thus far yielded a significant portion of the Neandertal genome, including over one million base pairs of hominoid nuclear DNA sequences, giving us the confidence to commence with the sequencing of the entire Neandertal genome," explained Svante Pbo, Ph.D., Director of the Department of Evolutionary Anthropology at the Max Planck Institute and lead author of the Nature article. "Sequencing the Neandertal genome offers the unique possibility to identify genetic changes specific to the genome of anatomically fully modern humans."

A parallel study on the same Neandertal sample also appears online in the journal Science this week. "The study was performed with conventional library preparation and more than 90% of the base pairs generated were from 454 Sequencing,." continued Dr. Pbo, co-author of the Science paper.

"The publication of articles in both Nature and Science is further validation of 454 Sequencing technology and demonstrates that we are the emerging gold standard for broad, fast and accurate sequencing of any genome, even one from highly degraded samples," said Christopher McLeod, President and CEO o
'"/>

Contact: Ben Carmichael
benjamin.carmichael@eurorscg.com
212-845-4242
Noonan/Russo Communications
15-Nov-2006


Page: 1 2

Related biology news :

1. UT and Atom Sciences Collaborate on NIH grant to develop test for major african disease
2. 454 Life Sciences and Baylor College of Medicine complete sequencing of DNA pioneer
3. Berkeley Lab Life Sciences division awarded NIH grants for fruit fly, nematode studies
4. University of Arizona neurobiologist John Hildebrand elected to the National Academy of Sciences
5. Dr. Michael Petrides: Elected to the American Academy of Arts and Sciences
6. Einsteins Dr. Vern Schramm elected to the National Academy of Sciences
7. 5 Stanford professors elected to National Academy of Sciences
8. National Academy of Sciences elects 2 Rutgers professors
9. Salk scientist Ursula Bellugi elected to National Academy of Sciences
10. National Academy of Sciences elects 2 Brandeis University scientists to membership
11. Psychology professor elected to American Academy of Arts and Sciences

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/29/2018)... ... November 29, 2018 , ... ACEA Biosciences , now ... Engineering Research Center for Cell Manufacturing Technologies (CMaT). CMaT is a ... and technologies for the consistent, scalable and low-cost production of high-quality living therapeutic ...
(Date:11/27/2018)... ... November 26, 2018 , ... uBiome, the ... of the website IBDwatch and Gastroenterology Fellow at the University of Louisville, to ... around the world, Dr. Wuerth will bring to uBiome knowledge and research on ...
(Date:11/27/2018)... CARLSBAD, Calif. (PRWEB) , ... November 27, 2018 ... ... & Sons. The companies have worked together to integrate the LabArchives Classroom ... students. The combined offering will be available beginning January of 2019. ...
Breaking Biology News(10 mins):
(Date:12/5/2018)... ZOETERMEER, Netherlands (PRWEB) , ... December 05, 2018 , ... ... last week paid tribute to in the European Parliament by Carlos Moedas, the European ... High-Level Conference EU Research and Innovation in Our Daily Lives, Commissioner Moedas spoke at ...
(Date:11/28/2018)... ... 2018 , ... Earlier this month, Lajollacooks4u's Founder and Chef Jodi Abel traveled ... of truffle season. , Her first stop was Umbria, a region in ... Black Truffle Lodge in the small mountain village of Pettino, Chef Jodi was introduced ...
(Date:11/20/2018)... ... November 19, 2018 , ... Patients with missing teeth in Sandy ... from Dr. Dan Myers at THE DENTIST Centers without a referral. Dr. Myers ... for the last 20 years. He now offers skilled dental care in two practice ...
(Date:11/13/2018)... ... 13, 2018 , ... Renowned Honolulu veterinarian, Dr. Patrick Leadbeater, has begun offering ... Dr. Leadbeater, of Kahala Pet Hospital on Oahu, is a skilled surgeon ... to the island of Kauai on an almost weekly basis to perform surgery at ...
Breaking Biology Technology:
Cached News: