lood lipids like LDL, typically known as the "bad cholesterol". Drugs in the classes known as thiazolidinediones and glitazars activate PPAR and are often used to manage high cholesterol and risk for Type 2 diabetes.
In the current study, the rats that received cherries had both a lower level of fat in their livers, and a higher expression of the PPAR gene, than those that did not and the correlation between the two was dose-dependent.
Now, the Cardioprotection Laboratory team has embarked on a new study in rats that have Type 2 diabetes, both with and without obesity and in the presence of low-fat and high-fat diets. They will look at whether tart cherries have an impact on the storage of fat in fat tissue and in muscle, and on the production of specific blood lipids like LDL and HDL. In addition, they will characterize cherries chemically, to assess the levels of phytochemicals in whole cherries, cherry juice and dry cherries.
Meanwhile, U-M Integrative Medicine co-director Sara Warber. M.D., an assistant professor of family medicine at the U-M Medical School, will lead a pilot clinical trial of whole tart cherries in humans. The study will enroll healthy individuals who will spend a night at the U-M General Clinical Research Center, and have their blood tested multiple times to look for the breakdown products of cherries.
Page: 1 2 3 4 Related biology news :1
Contact: Kara Gavin
University of Michigan Health System
. Corn, oats, cherries and red wines high melatonin content can help delay aging2
. Climate change and permafrost thaw alter greenhouse gas emissions in northern wetlands3
. Prenatal alcohol exposure alters brain activity in the frontal-striatal areas4
. Antibody-altering protein found in developing B cells5
. New research seeks to enhance alternative fuel integration in public vehicle fleets6
. Researchers identify genetic mutation that may alter tumor cell proliferation7
. Regulating alternative splicing during neural development8
. UGR researchers design an alternative to blood test to detect drugs in the body9
. Cigarette smoke alters DNA in sperm, genetic damage could pass to offspring10
. Study identifying alteration in gene associated with uterine cancer11
. Effect on breast tumors of DNA alternations in 3 genes described