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A compound from olive-pomace oil gets 80 percent slowing down of HIV spread

cid inhibited replication of a primary HIV-1 isolate. For 25 g/ml a decrease in the cytopathic effect and in p24 antigen levels in the supernatant culture medium was detected. For 30 g/ml, there was total absence of the cytopathic effect and also a decrease of p24 antigen levels.

Pilot Plant

The UGR Faculty of Sciences hosts a unique maslinic acid production pilot plant where the company MANINVEST S.L. staffing scientists from the UGR departments of Organic Chemistry, Biochemistry and Parasitology, as well as a coordinating economist is carrying out research on technology implementation and business programmes tuning aimed at making manitol and maslinic and oleanolic acids programmes more profitable.

Whilst manitol is obtained from olive oil waste water (alpechn) and olive-tree leaves, both acids are extracted from dry olive-pomace oil (orujo) produced at the olive-milling stage during olive oil elaboration process.

To this day, only oleanolic acid produced in China has been marketed. However, maslinic acid has gained importance as it is not still on the market and has a greater biological activity.

Prof. Andrs Garca-Granadoss team intends to continue working in the design and implementation of new maslinic acid by-products to fight against HIV, as well as in other innovative research projects financed by the Spanish Ministry of Science and Technology and the Andalusian Regional Government.


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Contact: Professor Andrs Garca-Granados Lpez de Hierro
agarcia@ugr.es
34-958-243-364
Universidad de Granada
9-Jul-2007


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