HOME >> BIOLOGY >> NEWS
A novel virus for croup

A forthcoming paper in the international, open-access journal PLoS Medicine makes the strongest association yet between a newly identified virus and the pediatric respiratory disease commonly known as croup. Following their recent description of the coronavirus HCoV-NL63, Lia van der Hoek and colleagues suggest this is one of the most frequently detected viruses in children with lower respiratory tract infections (LRTIs). These infections are estimated by the World Health Organization to be responsible for one fifth of all deaths in children under five years old.

The team, including researchers from University Medical Centres in Amsterdam, Bochum and Freiberg, determined the incidence of this novel virus in a sample of children under three years old with such respiratory infections. Nine hundred and forty nine samples of nasopharyngeal secretions were collected from both hospitalized patients and outpatients in four different regions of Germany. The study found that forty-nine samples (5.2%) were positive for the virus HCoV-NL63 overall, with a greater incidence in outpatients (7.9%) than hospitalized patients (3.2%). Co-infection with two other viruses also known to be prominent in the cause of LRTIs, was also frequently observed.

The researchers also investigated the occurrence of HCoV-NL63 in cases of respiratory disease where no other virus could be detected. Here, a strong relationship with the clinical symptoms associated with croup was apparent: 43% of the HCoV-NL63 positive patients with high HCoV-NL63 load and absence of co-infection had croup, compared with 6% of HCoV-NL63 negative patients. Previous studies have reported trends in croup, such as the relative susceptibility of boys to the disease, its peak occurrence in the second year of life and its predominance in late autumn and earlier winter, that are matched by patterns of HCoV-NL63 occurrence.

This systematic association of croup with HCoV-NL63 is particularly time
'"/>

Contact: Paul Ocampo
press@plos.org
415-624-1224
Public Library of Science
22-Aug-2005


Page: 1 2

Related biology news :

1. CTRC enrolls first patients in novel phase II study for sarcoma -- living virus destroys cancer cell
2. UB scientist discovers novel iron-copper alliance
3. A novel molecular dictator with a conscience discovered
4. Researchers pit novel version of common virus against cancer
5. UCLA researchers discover novel pathway that may promote immune system balance
6. pHLIP, a novel technology to locate and treat tumors
7. Bioluminescence at the service of a novel cerebral imaging technique
8. Application of Genomatix in silico methods reveals novel cancer associated genes
9. Two studies: Speeding development of novel tracer for prostate cancer
10. Erythrocyte G protein as a novel target for malarial chemotherapy
11. U of MN researchers find novel genes critical in organ development

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/26/2020)... ... August 25, 2020 , ... Catalent, the leading global provider ... gene therapies, and consumer health products, today announced that two Catalent Biologics experts ... taking place between Aug. 31 – September 4, 2020. , On Wednesday, Sept. ...
(Date:8/23/2020)... Texas (PRWEB) , ... August 21, 2020 , ... ... Rigaku Corporation has been published and is now available on the ... crystal X-ray diffraction—serves the X-ray analysis community, presenting current news and crystallographic research. ...
(Date:8/21/2020)... ... August 19, 2020 , ... “How can ... businesses dedicated to Salivary Bioscience for more than twenty years. Together with Douglas ... Springer, " Salivary Bioscience: Foundations of Interdisciplinary Saliva Research and Applications ," and ...
Breaking Biology News(10 mins):
(Date:7/22/2020)... TORONTO (PRWEB) , ... July 22, 2020 , ... Join ... and John Lorenc, Sr. Manager Regulatory Solutions, in a one hour live webinar ... is the regulating body in China for drugs and medical devices. Specifically, for medical ...
(Date:7/10/2020)... (PRWEB) , ... July 08, 2020 , ... ... services and products, announces a significant expansion of laboratory operations through its ... for agencies implementing testing programs. , Bode-CARES provides a turnkey ...
(Date:7/7/2020)... ... July 06, 2020 , ... Bio-IT World has announced the ... Squibb, the University of Chicago, Massachusetts General Hospital, Mission: Cure, and the Pistoia ... program, highlighting outstanding examples of how technology innovations and strategic initiatives can be ...
(Date:6/28/2020)... Calif. (PRWEB) , ... June 25, 2020 , ... ... researchers are racing to develop a vaccine or drug treatment. In an effort ... Recursion has publicly released the world’s largest imaging dataset portraying therapeutic compound ...
Breaking Biology Technology:
Cached News: