HOME >> BIOLOGY >> NEWS
A plastic pill for periodontal problems

NEW BRUNSWICK/PISCATAWAY, N.J. Rutgers scientists today announced a revolutionary new treatment for killing the bacteria that attack gum tissue during periodontal disease, while also promoting healing and the regeneration of tissue and bone around the teeth.

Eight to 12 percent of Americans have periodontal disease serious enough to require some type of advanced treatment, such as surgery. Left untreated, the condition can lead to tooth loss.

The breakthrough technology a polymer-based drug delivery system that may be implanted in pockets between the teeth and the gum developed at Rutgers, The State University of New Jersey, was presented at the 232nd National Meeting of the American Chemical Society in San Francisco by Michelle Johnson, a graduate student in the research group of paper co-author Kathryn Uhrich, a professor of chemistry and chemical biology at Rutgers.

"There has never been anything like this available to clinicians and it will certainly find a very prominent role in periodontal therapy in the future," said Mark Reynolds, chair of the department of periodontics at the University of Maryland Dental School, who collaborates with Uhrich on the research.

The new polymer or "plastic" material, when inserted between tooth and diseased gum, treats the bacterial infection, inflammation and pain with pharmaceuticals incorporated into the material itself, Johnson explained. It employs salicylic acid, the active ingredient in aspirin, for the swelling and discomfort, and three antimicrobials each with a different release rate compounds of clindamycin, chlorhexidrine and minocycline.

Once implanted, the polymer gradually breaks down to release the salicylic acid, which relieves pain and reduces inflammation, and the antimicrobials which inhibit infection at a sustained pace, Uhrich added.

Periodontal disease occurs when plaque that forms on the tooth surface spreads and grows below the gum line. Th
'"/>

Contact: Joseph Blumberg
blumberg@ur.rutgers.edu
732-932-7084 x652
Rutgers, the State University of New Jersey
14-Sep-2006


Page: 1 2

Related biology news :

1. Negative effects of plastics additive blocked by nutrient supplements
2. Engineers develop process to recycle unused paint by blending it into common plastics
3. Vitamin C and water not just healthy for people -- healthy for plastics, too
4. Carnegie Mellon scientists use green approach to transform plastics manufacturing
5. New wood-plastic composites to boost industry, help use waste products
6. Iowa State corn/soy plastics to be made into hog feeders
7. Cortical plasticity: its time to get excited about inhibition
8. Study provides insight into how the brain loses plasticity of youth
9. Potato blight pathogenicity explained by genome plasticity
10. Microbes convert Styrofoam into biodegradable plastic
11. Herbal supplements, a smoking gun in plastic surgery

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/6/2019)... ... 2019 , ... VetStem Biopharma has long been ... experience. In November it spun out a human regenerative medicine subsidiary, ... of the first cGMP cell manufacturing facilities in California , VetStem signed ...
(Date:8/6/2019)... ... August 05, 2019 , ... ... announce its attendance at the Microscopy & Microanalysis 2019 Meeting ( M&M 2019 ... Oregon Convention Center. , The Microscopy & Microanalysis Meeting, organized by the Microscopy ...
(Date:8/4/2019)... ... August 02, 2019 , ... Stay on top of current hot topics ... industries. Access to all webinars is free, so be sure to register today to ... Visit http://www.xtalks.com to see our upcoming webinars: , CLINICAL OPERATIONS , August ...
Breaking Biology News(10 mins):
(Date:8/23/2019)... ... August 22, 2019 , ... An upcoming ... is scheduled to broadcast 4Q/2019. Check your local listings for more information. , ... generic drug delivery. Focusing on therapeutics for children and the elderly, viewers will ...
(Date:8/14/2019)... COLLEGE, Pa. (PRWEB) , ... August 13, 2019 ... ... in nuclear receptor and in vitro toxicology testing solutions, announced the appointment of ... healthcare industry experience to the Board. , Mark McLoughlin will lend his healthcare ...
(Date:8/8/2019)... ... August 08, 2019 , ... ... for sales and service organizations, today announced that the company’s Studio Intelligent ... for the IVA market . Inference will officially accept the award at Frost ...
(Date:8/6/2019)... DIEGO (PRWEB) , ... August 06, 2019 , ... ... Marketing Radio (LSMR) have joined forces in launching the biweekly SDBN BUZZ podcast ... further growth. SDBN BUZZ podcast will also serve to promote the region and ...
Breaking Biology Technology:
Cached News: