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A prickly subject: The sea urchin genome is sequenced

fan base among scientists. One reason it was chosen for the genome-sequencing project is the size of the sea urchin research community. Over 140 laboratories are using sea urchins as a primary research organism. Annotation of the sequenced genome was conducted by 240 scientists in 11 countries.

In fact, it was research conducted on sea urchins over a hundred years ago that led to one of the breakthroughs of modern biology, when Theodor Boveri discovered in 1902 that normal development requires that every cell in an embryo have a full set of chromosomes carrying the genetic or inherited material for an organism.

One reason sea urchins have been so popular with scientists is that they are easy to work with. They can live in a laboratory comfortably, release their eggs readily, and have transparent embryos. That makes it easy to observe their fertilization and development, which is surprisingly similar to human embryonic development in some ways. As Dr. Coffman says, "Studying gene function and regulation in early sea urchin embryos is relatively easy compared with other model organisms such as mice, and much faster."

Sea urchins are also incredibly fecund. A single female discharges millions of eggs. In fact, most of an urchin's body mass consists of its reproductive organs, and that's what people are consuming when they eat the "roe" from a sea urchin.

At first glance, sea urchins seem to be inanimate, although people who have been around sea urchins know that the spines will move quickly in reaction to a light touch. The genome project, however, revealed that urchins have genes encoding some of the same sensory proteins involved in vision and hearing in humans. Yet the sea urchin has no eyes and ears, at least as we know them. Some of the visual sensory proteins are localized to an appendage known as the tube foot, and probably function in sensory processes there.

"The sea urchin r
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Contact: Jerilyn Bowers
jeri@mdibl.org
207-288-3147
Mount Desert Island Biological Laboratory
9-Nov-2006


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Related biology news :

1. Sea urchin genome suprisingly similar to man and may hold key to cures
2. Sea urchin genome is a biology boon and a computational feat
3. Decoded sea urchin genome shows surprising relationship to humans
4. Insight into evolution of adaptive immunity boosted by sea urchin genome sequencing
5. Carnegie Mellon scientist plays key role in unveiling sea urchin genome
6. Decoded sea urchin genome shows surprising relationship to man
7. Sea urchins unexpectedly diverse innate immune capability points to new research avenue
8. How the sea urchin grows new spines
9. Unravelling new complexity in the genome
10. One species, many genomes
11. First genome-wide study of infectious disease opens new avenues for HIV treatment, vaccines

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