HOME >> BIOLOGY >> NEWS
A tNOX-based protocol for early detection of lung cancer in smokers and nonsmokers

CHICAGO -- Lung cancer is a formidable disease. While it is one of the most preventable cancers, with the vast majority of 160,000 annual deaths in the United States due to smoking, it is invariably difficult to find early when it is most amenable to treatment. As a result, it remains the top cancer killer in the nation.

But a new test for the early detection of lung cancer that involves measuring levels of a certain protein may provide hope for thousands of smokers worldwide. While the findings are preliminary and involve a small group of subjects, the researchers see their early results as extremely promising.

Results were presented at the first meeting on Molecular Diagnostics in Cancer Therapeutic Development, organized by the American Association for Cancer Research.

A team led by Dorothy M. Morre, Ph.D., professor of foods and nutrition at Purdue University in West Lafayette, Indiana, and D. James Morre, Ph.D., distinguished professor of medicinal chemistry at Purdue, wanted to come up with a robust lung cancer screening procedure for people who smoke.

"We'd like to have a means of detecting lung cancer early in individuals who smoke with a low incidence of false positives," Dorothy Morre said. "There's apparently no good method of finding this and there is a lot of interest at the National Cancer Institute in developing such a protocol."

The Morres -- along with colleagues at Purdue, NOX Technologies, Inc., also in West Lafayette, and at Mount Sinai Medical Center in New York -- focused their efforts on a protein called tNOX, a member of a family of proteins that are involved in cell growth. Normal cells express the NOX enzyme only when they are dividing in response to growth hormone signals. In contrast, cancer cells have gained the ability to express NOX activity at all times. This overactive form of NOX, known as tNOX for tumor-associated NOX has long been assumed to be vital for the growth of cancer cell
'"/>

Contact: Warren Froelich
froelich@aacr.org
215-440-9300
American Association for Cancer Research
13-Sep-2006


Page: 1 2 3

Related biology news :

1. Newborn hearing screening programs may benefit from the standardization of testing protocols
2. The American Physiological Society publishes resource book for animal exercise protocols
3. New protocol tracks how land use influences the way streams work
4. New cyber security protocol for online banking, and more
5. An early ape shows its hand
6. Purdue-IU researchers explore new method for early disease diagnosis
7. Nearly 90 percent of babies receive recommended newborn screening tests
8. A first-principles model of early evolution
9. New blood test might offer early warning of deep belly fat
10. Marine worm opens new window on early cell development
11. Modular leukemia drug shows promise in early testing

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/6/2016)... Dec. 6, 2016 Valencell , the leading ... has seen a third consecutive year of triple digit ... in 2016 with a 360 percent increase in companies ... increase was driven by sales of its wrist and ... in its technology for hearables for fitness and healthcare ...
(Date:12/2/2016)... AUSTIN, Texas , Dec. 1, 2016 /PRNewswire/ ... provider, today announced BioLock , an electrocardiogram ... and health monitoring, a key IoT asset. The ... embedded into a vehicle,s steering wheel and mobile ... a simple touch. As vehicle technology ...
(Date:11/29/2016)... , Nov. 29, 2016   ... identification and object recognition technologies, today released ... for fingerprint recognition solutions that run on ... fingerprint template using less than 128KB of ... compact devices that have limited on-board resources, ...
Breaking Biology News(10 mins):
(Date:12/8/2016)...  The Board of Directors of the Pittsburgh ... only pure life sciences investment firm, today ... succession plan developed by the Nominating and Governance Committee ... (Jim) F. Jordan is selected to serve as ... Manzetti , who is elected to the position of ...
(Date:12/8/2016)... AskLinkerReports.com has published a report on Amyloglucosidase Market ... Market Research Report. From a basic outline of the Amyloglucosidase ... covered in the report. This report projects investment feasibility analysis, ... Amyloglucosidase industry. ... , Complete report on ...
(Date:12/8/2016)... ... December 08, 2016 , ... Opal Kelly, ... essential device-to-computer interconnect using USB or PCI Express, announced the FOMD-ACV-A4, the company's ... is a small, thin, SODIMM-style module that fits a standard 204-pin SODIMM socket ...
(Date:12/8/2016)... (PRWEB) , ... December 08, ... ... announces the commercial launch of flexible packaging for their exceptionally efficient human ... bag system extends RoosterBio’s portfolio of bioprocess media products engineered to radically ...
Breaking Biology Technology:
Cached News: