HOME >> BIOLOGY >> NEWS
A unique arrangement for egg cell division

Heidelberg, 09 August 2007 - Which genes are passed on from mother to child is decided very early on during the maturation of the egg cell in the ovary. In a cell division process that is unique to egg cells, half of the chromosomes are eliminated from the egg before it is fertilised. Using a powerful microscope, researchers from the European Molecular Biology Laboratory (EMBL) have now revealed how the molecular machinery functions that is responsible for chromosome reduction of egg cells in mice. In the current issue of Cell they report the assembly of this machinery, which is very different from what happens in all other cells in the body. The process is likely conserved across species and the new insights might help shed light on defects occurring in human egg cell development.

The first step in the development of an egg cell is the division of its progenitor cell, the oocyte. Unlike other cells in the body, an oocyte does not divide equally to produce two identical daughter cells. Instead, it undergoes a reducing division, which halves its genetic material to generate a single egg cell with 23 instead of the normal 46 chromosomes in humans. It is crucial that the egg has half the normal set of chromosomes, because the second half is brought in by the sperm cell during fertilisation. The molecular apparatus that makes sure that the egg ends up with the correct number of chromosomes is a bipolar spindle consisting of protein filaments, called microtubules that are part of the cells skeleton. Spindle microtubules attach themselves to the chromosomes, separate them and pull one half out of the oocyte into a small polar body that is later discarded.

Microtubule spindles are found in all dividing cells. What is special about oocytes is that they lack specialised spindle-forming organelles, called centrosomes, says Jan Ellenberg, Coordinator of the Gene Expression Unit at EMBL, all other cells contain two centrosomes from where the microtubules originate.
'"/>

Contact: Lena Raditsch
lena.raditsch@embl.de
49-622-138-78125
European Molecular Biology Laboratory
9-Aug-2007


Page: 1 2

Related biology news :

1. Genomics study provides insight into the evolution of unique human traits
2. Geologists witness unique volcanic mudflow in action in New Zealand
3. Liverpool amongst first in UK to install unique DNA sequencing technology
4. UD awarded $11M for osteoarthritis research and unique mentoring program for women scientists
5. Tumor vessels identified by unique molecular markers
6. New DNA study helps explain unique diversity among Melanesians
7. A unique twin study on the increased cardiometabolic risk in obesity
8. DNA gets new twist: Carnegie Mellon scientists develop unique DNA nanotags
9. New studies find amazing concentration of species unique to East African mountains
10. Dartmouth researchers find that arsenic triggers unique mechanism in rare leukemia
11. New study pinpoints unique genetic susceptibility for viral encephalitis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/18/2019)... ... June 18, 2019 , ... Cirrascale ... introduced Data Science Workstations-as-a-Service as part of its dedicated, multi-GPU, deep learning cloud ... Data Science Workstations feature NVIDIA® Quadro RTX™ GPUs for up to 260 teraflops ...
(Date:6/14/2019)... Va. (PRWEB) , ... June 14, 2019 , ... Molecular ... is estimated to be $8,760 million in 2019. Major segments that are expected ... These are all broken out and forecasted as segments in Kalorama’s The World ...
(Date:6/11/2019)... ... 12, 2019 , ... With a rapidly growing customer base ... Geneious Biologics platform as a premium hub for bioinformatics and computer programming capabilities. ... Geneious team has done an excellent job accommodating our specific data, resulting in ...
Breaking Biology News(10 mins):
(Date:5/2/2019)... ... 2019 , ... Stay on top of current hot topics through free webinars ... all webinars is free, so be sure to register today to save your place! ... to see our upcoming webinars: , CLINICAL TRIALS , May 7 – Oncology ...
(Date:5/2/2019)... ... May 02, 2019 , ... Boston Robotic Hair Restoration ... Gone are the days of painful hair transplant procedures. Boston Robotic Hair Restoration ... the only robotic intelligent solution to offer a minimally invasive procedure. With the ...
(Date:4/25/2019)... SAN FRANCISCO (PRWEB) , ... April 24, 2019 ... ... Intelligent Virtual Agents for sales and service organizations, today announced global ... contact center software providers and enterprises of all sizes to harness the power ...
(Date:4/16/2019)... ... April 16, 2019 , ... On April ... partner, the U.S. Army Center for Environmental Health Research (USACEHR), with an award ... , Blue Sources, a veteran-owned company located at the Frederick Innovative Technology Center, ...
Breaking Biology Technology:
Cached News: