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AACR, FDA and NCI announce cancer biomarkers collaborative at the AACR 2007 annual meeting

LOS ANGELES The American Association for Cancer Research, together with the Food and Drug Administration and National Cancer Institute, today announces the formation of the AACR-FDA-NCI Cancer Biomarkers Collaborative (CBC) to facilitate the use of validated biomarkers in clinical trials and ultimately in evidence-based oncology and cancer medicine.

The Collaborative brings together leaders from academia, government, industry, and patient advocacy groups to develop a set of guidelines for effectively integrating predictive biomarkers into clinical trials.

"Major advances in cancer biology over the last quarter century have provided us with a better fundamental understanding of cancer in all of its forms, yet the translation of this knowledge into medical practice remains painstakingly slow," said William N. Hait, M.D., Ph.D., President of the American Association for Cancer Research. "Therefore, we are joining forces with our partners to find new ways of exploring the use of biomarkers in cancer detection and treatment, without sacrificing high standards for safety and efficacy."

"The FDA's Critical Path is an important initiative that aims to modernize the processes and methods used to evaluate the safety, efficacy and quality of medical products as they move from product selection and design to mass manufacture," said Samir Khleif, M.D., of the NCI and Special Assistant to the FDA Commissioner.

The Collaborative evolved from a special "Think Tank" session of academic, industry and government researchers and patient advocacy groups held at AACR's headquarters in Philadelphia in November, 2006. Think Tank participants laid the groundwork for the new collaborative and identified four priority areas of research to focus on: biospecimens, bioinformatics, assay validation, and information sharing.

This summer, the Collaborative will meet again in Philadelphia to discuss various aspects of these four are
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Contact: Staci Vernick Goldberg
goldberg@aacr.org
267-646-0616
American Association for Cancer Research
17-Apr-2007


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