Philadelphia The American Association for Cancer Research announces the first 11 recipients of the new Jeannik M. Littlefield-AACR Grants in Metastatic Colon Cancer Research. The awards, ranging to $250,000, were established in February 2006, to support innovative research projects designed to accelerate the discovery and development of new agents to treat metastatic colon cancer. Grant awards were selected through a rigorous and highly competitive process by a committee of accomplished senior scientists. AACR is currently distributing a total of $2,644,977 to the successful investigators.
"Among the 114 applications submitted, these 11 awardees were judged to have the most merit," said David Irwin, Ph.D., managing director of the Science and Education Division of the AACR. "We offer our sincere congratulations to the investigators, and anticipate they will make substantial contributions to this field of cancer research."
The Jeannik M. Littlefield-AACR Grants in Metastatic Colon Cancer Research are sponsored by Jacques and Sandy Littlefield of Portolo Valley, California, who donated $3 million to the AACR in late 2005. They are named for Mr. Littlefield's mother.
Recipients of the 2006 Jeannik M. Littlefield-AACR Grants in Metastatic Colon Cancer Research are:
Peter Carmeliet, M.D., Ph.D., Flanders Interuniversity Institute for Biotechnology, "Preclinical Development of anti-P1GF Antibodies for Metastatic Colon Cancer." In the quest to block angiogenesis, this study will test a homologue of VEGF P1GF. Antibodies to P1GF will be used in cell lines and xenograft models. The approach has strong potential for clinical application because blocking P1GF should not interfere with normal angiogenesis.
Steven A. Curley, M.D., University of Texas M.D. Anderson Cancer Center, "Carbon Nanotubules and Gold Nanoparticles as Radiofrequency Targets." The goals are to couple antibodies to nanotubules a