In their new research, scheduled for publication in the June 13 issue of Biochemistry, Paul Wentworth, Jr., and colleagues report that atheronals do have the potential to cause plaques. Atheronals accelerate or stimulate a number of processes regarded as critical for formation of atherosclerotic plaques, they found.
The Biochemistry report raises the possibility that atheronals may originate in part from ozone inhaled into the lung from polluted air. "As such, the atheronals may be a heretofore unrecognized chemical player in the known linkage between environmental pollution and cardiovascular disease," the report states.
ARTICLE #1
"Proatherogenic Effects of the Cholesterol Ozonolysis Products, Atheronal-A and Atheronal-B."
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CONTACT:
Paul Wentworth, Jr., Ph.D., FRSC
The Scripps Research Institute
Phone: 858-784-2576
Fax: 858-784-2593
Email: paulw@scripps.edu, paul.wentworth@bioch.ox.ac.uk
ARTICLE #2
A dozen cloves of garlic a day keeps the doctor away?
Journal of Agricultural & Food Chemistry
The classic fairy tale Goldilock
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Contact: Michael Woods
m_woods@acs.org
202-872-4400
American Chemical Society
30-May-2006