HOME >> BIOLOGY >> NEWS
Abundance of myostatin in infected swine may result in reduced muscle mass

CHAMPAIGN, Ill. -- A study looking at chronic infectious respiratory diseases that affect most swine during their critical growing stage has shed new light on the reasons for restricted weight gain and reduced muscle mass.

In the November issue of the Journal of Nutrition, scientists at the University of Illinois at Urbana-Champaign report that the production of inflammatory cytokines by immune cells appears to be responsible for declines of both protein accretion and weight gain in swine infected with Porcine Reproductive and Respiratory Syndrome Virus (PRRSV).

The study also suggests that myostatin, a protein that limits muscle growth, is overproduced during infection, thereby reducing the growth of skeletal muscle, said Rodney W. Johnson, a professor in the department of animal sciences and the interdisciplinary Division of Nutritional Sciences.

Johnson and colleagues isolated pigs in disease-containment chambers and exposed different experimental groups to the bacterium Mycoplasma hyopneumoniae and/or PRRSV.

Almost all U.S. swine are exposed to the bacterium in production facilities, while about 60 percent are exposed to PRRSV. These pathogens open the way for other infectious agents. During the pivotal growing stage, pigs are at the most risk and suffer from cough, fevers and depressed appetite. Reduced market weight or increased time for pigs to reach a desired market weight can be a substantial cost to producers.

Infection from the bacterium alone did not reduce weight gain compared with the control group during the four-week-long experiment, but it did lead to the development of lesions that affected 8 percent of the total lung area in infected pigs. The finding was similar to earlier work in Johnson's laboratory. However, the introduction of PRRSV caused damage to the lungs from the bacterium to jump to 40 percent.

"One thing the virus does is suppress the immune system," Johnso
'"/>

Contact: Jim Barlow, Life Sciences Editor
jebarlow@uiuc.edu
217-333-5802
University of Illinois at Urbana-Champaign
17-Nov-2004


Page: 1 2

Related biology news :

1. Identified mechanism in the malaria parasite to help it adapt to infected individuals
2. Major breakthrough in understanding how HIV interferes with infected cell division
3. Manganese levels increase in scrapie-infected sheep before clinical symptoms develop
4. Anti-herpes treatment reduces HIV levels in women infected with both viruses
5. Antiretroviral resistance testing in HIV infected patients improves health and saves costs
6. Meth promotes spread of virus in HIV-infected users
7. HIVs cellular kiss of death explains loss of uninfected T cells in AIDS
8. Higher risk for cervical cancer seen among women infected with multiple HPV types
9. Viral protein helps infected T cells stick to uninfected cells
10. Zinc supplements safe for HIV-infected children
11. Mosquitoes are more attracted to individuals infected with malaria

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Abundance myostatin infected swine may result reduced muscle mass

(Date:8/3/2015)... SAN JOSE, Calif. , Aug. 3, 2015 /PRNewswire/ ... developer of human interface solutions, today announced that members ... investment community at the Pacific Crest Global Technology Leadership ... Mountain Time. The conference will be held at the ... The presentation may include forward-looking information. ...
(Date:7/31/2015)... Chine, 31 juillet 2015 La 10e ... ) sera organisée par le BGI du 22 ... en Chine. La conférence ... inauguration en 2006, l,ICG est devenue l,une des ... domaine des « omiques » et c,est aussi la plus ...
(Date:7/31/2015)... 2015 The 10 th International Conference on ... October 22-25, 2015, in Shenzhen , ... celebrating its 10 th anniversary this year. Since its inauguration ... influential annual meetings in the ,omics, fields, and is one ... ICG-10 focuses on recent breakthroughs and advances in ...
Breaking Biology News(10 mins):La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 2La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 3The 10th International Conference on Genomics (ICG-10) to Open in October 2
(Date:8/27/2015)... Aug. 27, 2015  Asterias Biotherapeutics, Inc. (NYSE MKT: ... of regenerative medicine, today announced that executives from the ... month of September.  , Pedro ... & Renshaw,s 17th Annual Global Investment Conference on Wednesday, ... St. Regis Hotel in New York City ...
(Date:8/27/2015)... ... August 27, 2015 , ... METTLER TOLEDO's web-based EasyFinder™ ... product choices to a manageable shortlist of bench and floor scales and terminals. ... fit best with the customer’s industry and application. , Side-by-side product comparisons ...
(Date:8/26/2015)... Aug. 26, 2015  Roka Bioscience, Inc. (NASDAQ: ... advanced testing solutions for the detection of foodborne pathogens, ... at the Sidoti & Company Emerging Growth Conference on ... held at the New York Marriott Marquis. ... available through the investor relations section of Roka Bioscience,s ...
(Date:8/26/2015)... August 26, 2015 Israel Proves Its Place ... 1 st place  Wayerz comes in 5 th ... Israel by venture capital fund JVP, with Chinese consulting ... China , Israel , ... Impressive achievement for the Israeli representatives in the final ...
Breaking Biology Technology:Asterias Biotherapeutics to Present at Upcoming Investor Conferences 2METTLER TOLEDO Updates Online Scale Selection Tool 2Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 2Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 3Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 4Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 5Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 6
Cached News: