HOME >> BIOLOGY >> NEWS
Abundance of myostatin in infected swine may result in reduced muscle mass

CHAMPAIGN, Ill. -- A study looking at chronic infectious respiratory diseases that affect most swine during their critical growing stage has shed new light on the reasons for restricted weight gain and reduced muscle mass.

In the November issue of the Journal of Nutrition, scientists at the University of Illinois at Urbana-Champaign report that the production of inflammatory cytokines by immune cells appears to be responsible for declines of both protein accretion and weight gain in swine infected with Porcine Reproductive and Respiratory Syndrome Virus (PRRSV).

The study also suggests that myostatin, a protein that limits muscle growth, is overproduced during infection, thereby reducing the growth of skeletal muscle, said Rodney W. Johnson, a professor in the department of animal sciences and the interdisciplinary Division of Nutritional Sciences.

Johnson and colleagues isolated pigs in disease-containment chambers and exposed different experimental groups to the bacterium Mycoplasma hyopneumoniae and/or PRRSV.

Almost all U.S. swine are exposed to the bacterium in production facilities, while about 60 percent are exposed to PRRSV. These pathogens open the way for other infectious agents. During the pivotal growing stage, pigs are at the most risk and suffer from cough, fevers and depressed appetite. Reduced market weight or increased time for pigs to reach a desired market weight can be a substantial cost to producers.

Infection from the bacterium alone did not reduce weight gain compared with the control group during the four-week-long experiment, but it did lead to the development of lesions that affected 8 percent of the total lung area in infected pigs. The finding was similar to earlier work in Johnson's laboratory. However, the introduction of PRRSV caused damage to the lungs from the bacterium to jump to 40 percent.

"One thing the virus does is suppress the immune system," Johnso
'"/>

Contact: Jim Barlow, Life Sciences Editor
jebarlow@uiuc.edu
217-333-5802
University of Illinois at Urbana-Champaign
17-Nov-2004


Page: 1 2

Related biology news :

1. Identified mechanism in the malaria parasite to help it adapt to infected individuals
2. Major breakthrough in understanding how HIV interferes with infected cell division
3. Manganese levels increase in scrapie-infected sheep before clinical symptoms develop
4. Anti-herpes treatment reduces HIV levels in women infected with both viruses
5. Antiretroviral resistance testing in HIV infected patients improves health and saves costs
6. Meth promotes spread of virus in HIV-infected users
7. HIVs cellular kiss of death explains loss of uninfected T cells in AIDS
8. Higher risk for cervical cancer seen among women infected with multiple HPV types
9. Viral protein helps infected T cells stick to uninfected cells
10. Zinc supplements safe for HIV-infected children
11. Mosquitoes are more attracted to individuals infected with malaria

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Abundance myostatin infected swine may result reduced muscle mass

(Date:6/24/2015)... 2015 Research and ... the "Huawei Ascend Mate 7 Fingerprint Sensor ... offering. Huawei,s technological choice for the ... than Apple,s and Samsung,s one. The Ascend Mate ... Fingerprint Cards, a main actor in capacitive sensing ...
(Date:6/23/2015)... June 23, 2015  Crossmatch™, a leading ... today announced enhanced functionality of its DigitalPersona ... The enhancements build on the native flexibility ... Altus platform and provide expanded mobile credential ... In today,s environment of increasing cyber-attacks and ...
(Date:6/17/2015)... 2015  Synaptics Inc. (NASDAQ: SYNA ), ... that Xiaomi, one of the world,s largest mobile ... ® family of capacitive touchscreen solutions and ... for its latest smartphones, the Xiaomi Mi Note ... in-cell display solutions and DDICs in discrete display ...
Breaking Biology News(10 mins):Huawei Ascend Mate 7 Fingerprint Sensor - Reverse Costing Analysis 2Crossmatch Releases Enhanced DigitalPersona Altus Advanced Authentication Functionality 2Synaptics Touchscreen and Display Driver IC Solutions Power Xiaomi's Latest Flagship Smartphones 2Synaptics Touchscreen and Display Driver IC Solutions Power Xiaomi's Latest Flagship Smartphones 3
(Date:7/2/2015)... -- Amici Procurement Migrates to the Cloud ... has chosen Microsoft Cloud Solution Provider iomart ...      (Logo: http://photos.prnewswire.com/prnh/20121126/579634) , ... the bio-tech sector with a unique procurement service, helping ... help them obtain best value. Its IT platform hosts ...
(Date:7/2/2015)... ... July 02, 2015 , ... ... of surgical instruments in Orthopedics, announced today the acquisition of Turner Medical, ... largest provider of surgical instruments to the Spine Industry. The acquisition of Turner ...
(Date:7/1/2015)... and PARIS , July ... and Genective, key developer of biotech crops, today ... of new generations of insect control traits. ... to counter the realities of advancing insect resistance. ... AgBiome,s unique insect control technology with Genective,s capability ...
(Date:7/1/2015)... ... , ... The next-generation sequencing (NGS) clinical market is poised for huge growth ... BCC Research reveals in its new report that the market drivers of this vibrant ... need for better diagnostics as part of a molecular diagnostics trend. , The global ...
Breaking Biology Technology:Biotech Procurement Company Moves to Office 365 with iomart 2In'Tech Medical Acquires Turner Medical to Become a World Leader in Orthopedic Contract-Manufacturing 2In'Tech Medical Acquires Turner Medical to Become a World Leader in Orthopedic Contract-Manufacturing 3AgBiome and Genective collaborate to create novel insect-resistant crops 2NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 2NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 3
Cached News: