HOME >> BIOLOGY >> NEWS
Activating ATR

NOTE: This research was made available thru advanced online publication.

ATR coordinates the cellular response to DNA damage, both by sensing that damage has occurred, and helping to propagate the intracellular signal to fix it. But how ATR recognizes several disparate forms of DNA damage (ie., UV-induced cross-links, oxidative damage, and polymerase toxins) had remained elusive. Now, Dr. Karlene Cimprich and colleagues have identified how a single-stranded DNA structure can serve as a common intermediate to activate ATR in response to various forms of genotoxic stress. Emphasizing the importance of this finding, Dr. Cimprich explains that "Cells must properly detect and respond to DNA lesions, and this activity is critical for maintaining the integrity of the genome and the prevention of cancer."


'"/>

Contact: Heather Cosel
coselpie@cshl.edu
Cold Spring Harbor Laboratory
18-Apr-2005


Page: 1

Related biology news :

1. Waters off Washington state only second place in world where glass sponge reefs found
2. Pioneering approach to wastewater treatment earns Stanford engineer the 2007 Stockholm Water Prize
3. Water theory is watertight, researchers say
4. Water Treatment and Reuse -- II
5. Water filtration technique removes dangerous freshwater algae toxins
6. NJIT professor to address Water Industry Conference At Harvard Club about desalinating water
7. Caltechs Emmanuel Candes to receive $500,000 Waterman Award
8. Water management in cells
9. Water quality a major focus of $14 million grant to the University of Arizona
10. Water and the environment
11. National Academy news: Water quality improvement in southwestern Pennsylvania

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/2/2017)... LONDON , March 2, 2017 Who ... infringement lawsuits? Download the full report: https://www.reportbuyer.com/product/4313699/ ... ON THE FINGERPRINT SENSOR FIELD? Fingerprint sensors using ... smartphones. The fingerprint sensor vendor Idex forecasts an increase ... in mobile devices and of the fingerprint sensor market ...
(Date:2/28/2017)... DORTMUND, Germany , February 28, 2017 ... ... Amsterdam from 14 to 16 March, ... to destination, and show how seamless travel is a real benefit ... Materna has added biometrics to their passenger touch point solutions to ...
(Date:2/24/2017)... -- EyeLock LLC, a leader of iris-based identity authentication ... solution on the latest Qualcomm® Snapdragon™ 835 mobile ... Congress 2017 (February 27 – March 2, ... Stand 3E10. The Snapdragon 835 ... combination of hardware, software and biometrics technologies ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... BETHESDA, Md. , March 23, 2017 /PRNewswire/ ... company developing DCVax® personalized immune therapies for solid ... on the $7.5 million financing it announced last ... Company sold to several institutional investors securities totaling ... $.26 per share, and 10,000,000 shares of Class ...
(Date:3/23/2017)... ... March 23, 2017 , ... Ellen Matloff, president and ... Council (CTC) as a 2017 Women of Innovation® finalist. Matloff will be among ... Dinner. , The dinner recognizes women accomplished in science, technology, engineering and math ...
(Date:3/23/2017)... , March 23, 2017  Agriculture technology company ... A financing and note conversion to commercialize its Cool ... is focused on developing products that are simultaneously profitable ... million in the last 18 months. This latest round ... Bridge Venture Partners. The company,s primary ...
(Date:3/22/2017)... ... 22, 2017 , ... Researchers face a fundamental challenge as ... full-size tissues, bones, even whole organs to implant in people to treat disease ... into the developing tissue. , Current bioengineering techniques, including 3-D printing, can’t ...
Breaking Biology Technology:
Cached News: