HOME >> BIOLOGY >> NEWS
Activating ATR

NOTE: This research was made available thru advanced online publication.

ATR coordinates the cellular response to DNA damage, both by sensing that damage has occurred, and helping to propagate the intracellular signal to fix it. But how ATR recognizes several disparate forms of DNA damage (ie., UV-induced cross-links, oxidative damage, and polymerase toxins) had remained elusive. Now, Dr. Karlene Cimprich and colleagues have identified how a single-stranded DNA structure can serve as a common intermediate to activate ATR in response to various forms of genotoxic stress. Emphasizing the importance of this finding, Dr. Cimprich explains that "Cells must properly detect and respond to DNA lesions, and this activity is critical for maintaining the integrity of the genome and the prevention of cancer."


'"/>

Contact: Heather Cosel
coselpie@cshl.edu
Cold Spring Harbor Laboratory
18-Apr-2005


Page: 1

Related biology news :

1. Waters off Washington state only second place in world where glass sponge reefs found
2. Pioneering approach to wastewater treatment earns Stanford engineer the 2007 Stockholm Water Prize
3. Water theory is watertight, researchers say
4. Water Treatment and Reuse -- II
5. Water filtration technique removes dangerous freshwater algae toxins
6. NJIT professor to address Water Industry Conference At Harvard Club about desalinating water
7. Caltechs Emmanuel Candes to receive $500,000 Waterman Award
8. Water management in cells
9. Water quality a major focus of $14 million grant to the University of Arizona
10. Water and the environment
11. National Academy news: Water quality improvement in southwestern Pennsylvania

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Activating ATR

(Date:6/23/2015)... BEACH GARDENS, Fla. , June 23, ... multi-factor identity management and authentication solutions, today announced ... Altus strong, multi-factor authentication solution.  The enhancements ... of use of the DigitalPersona Altus platform ... biometric reader compatibility. In today,s ...
(Date:6/17/2015)... 2015  Synaptics Inc. (NASDAQ: SYNA ), ... that Xiaomi, one of the world,s largest mobile ... ® family of capacitive touchscreen solutions and ... for its latest smartphones, the Xiaomi Mi Note ... in-cell display solutions and DDICs in discrete display ...
(Date:6/16/2015)... GOTHENBURG, Sweden , June 16, 2015 ... 2015 from previously communicated that it will amount to at ... 390 MSEK. Due to the rapid increase in market growth ... from the previously communicated guidance that revenue for 2015 will ... 2015 will amount to approximately 2,200 MSEK. Due ...
Breaking Biology News(10 mins):Crossmatch Releases Enhanced DigitalPersona Altus Advanced Authentication Functionality 2Synaptics Touchscreen and Display Driver IC Solutions Power Xiaomi's Latest Flagship Smartphones 2Synaptics Touchscreen and Display Driver IC Solutions Power Xiaomi's Latest Flagship Smartphones 3Fingerprint Cards Raises the Revenue Guidance for Q2 2015 and for the Full Year 2015 2Fingerprint Cards Raises the Revenue Guidance for Q2 2015 and for the Full Year 2015 3
(Date:7/6/2015)... 29, 2015 Research ... addition of the "Biotechnology for the Non-Biotechnologist" ... for the Non-Biotechnologist, ideal for non-Scientists and Scientists ... and potential of biotechnology. Ideal for ... theory, principles, techniques, and potential of biotechnology ...
(Date:7/6/2015)... -- ImmunoCellular Therapeutics, Ltd. ("ImmunoCellular") (NYSE MKT: IMUC) today ... Clinical (Novella), to conduct the phase 3 registration ... Novella is a full-service, global clinical research organization (CRO) ... companies. The ICT-107 phase 3 trial will include approximately ... and Canada , and ...
(Date:7/3/2015)... , July 3, 2015 ... voivat hakea verkossa osoitteessa  http://www.openinnovationinscience.at ... Open Innovation in Science" -jatkokoulutusohjelmaan ... Boltzmann Gesellschaftin (LBG) tekemän, kansainvälisiä ... mukaan terveystieteiden kaksi suurinta haastetta ...
(Date:7/3/2015)... Forskare kan ansöka ... http://www.openinnovationinscience.at till det återkommande utbildningsprogrammet "Lab ... i Wien .  ... forskare och vetenskapsmän som genomfördes av Ludwig ... utmaningar bristen på incitament för att undersöka ...
Breaking Biology Technology:ImmunoCellular Therapeutics Establishes Agreement with Novella Clinical to Conduct ICT-107 Phase 3 Registration Trial in Glioblastoma 2Maailman ensimmäinen tiedemiesten koulutukseen suunniteltu avoimen innovaation ohjelma käynnistyy 2Maailman ensimmäinen tiedemiesten koulutukseen suunniteltu avoimen innovaation ohjelma käynnistyy 3Lansering av världens första program för öppen innovation för att utbilda forskare 2Lansering av världens första program för öppen innovation för att utbilda forskare 3
Cached News: