HOME >> BIOLOGY >> NEWS
Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin

GALVESTON, Texas -- In a fundamental discovery that someday may help cure type 1 diabetes by allowing people to grow their own insulin-producing cells for a damaged or defective pancreas, medical researchers here have reported that they have engineered adult stem cells derived from human umbilical cord blood to produce insulin.

The researchers announced their laboratory finding, which caps nearly four years of research, in the June 2007 issue of the medical journal Cell Proliferation, posted online this week. Their paper calls it "the first demonstration that human umbilical cord blood-derived stem cells can be engineered" to synthesize insulin.

"This discovery tells us that we have the potential to produce insulin from adult stem cells to help people with diabetes," said Dr. Randall J. Urban, senior author of the paper, professor and chair of internal medicine at the University of Texas Medical Branch at Galveston and director of UTMBs Nelda C. and Lutcher H. J. Stark Diabetes Center. Stressing that the reported discovery is extremely basic research, Urban cautioned: "It doesnt prove that were going to be able to do this in people its just the first step up the rung of the ladder."

The lead author of the paper, UTMB professor of internal medicine/endocrinology Larry Denner, said that by working with adult stem cells rather than embryonic stem cells, doctors practicing so-called regenerative medicine eventually might be able to extract stem cells from an individuals blood, then grow them in the laboratory to large numbers and tweak them so that they are directed to create a needed organ. In this way, he said, physicians might avoid the usual pitfall involved in transplanting cells or organs from other people organ rejection, which requires organ recipients to take immune-suppressing drugs for the rest of their lives.

Huge numbers of stem cells are thought to be required to create new organs. Researchers might remove th
'"/>

Contact: Tom Curtis
tcurtis@utmb.edu
409-772-2455
University of Texas Medical Branch at Galveston
25-May-2007


Page: 1 2 3

Related biology news :

1. Adult survivors of childhood leukemia exercise less, worsening high risk for obesity and illness
2. Adult stem/progenitor cells repair of damaged brain, pancreas, kidney cells newly understood
3. Adult stem cells to repair hearts damaged by severe coronary artery disease investigated
4. Adult neurogenesis newly adult-born neurons are functionally similar to mature neurons
5. Adults who go to bed lonely get stress hormone boost next morning
6. Adult stem cells are touchy-feely, need environmental clues
7. Adult stem cell research at UB targets damaged hearts
8. 4th International Conference on Teenage and Young Adult Cancer Medicine
9. Adult human neural stem cell therapy successful in treating spinal cord injury
10. Adult stem cells from adipose tissue could save lives
11. Adults can be retrained to learn second languages more easily, says UCL scientist

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/31/2020)... ... July 30, 2020 , ... Justin Zamirowski ... with a near term focus on Type 2 diabetes and associated comorbidities. , ... multiple therapeutic areas and classes. As Chief Commercial Officer, Justin will lead ...
(Date:7/10/2020)... ... ... Today CJ BIO announced the first in a series of Food Ingredient ... that is revolutionizing ingredient mixes, nutritional content and flavor profiles across a range of ... 2020 at11:00 AM (CDT) during SHIFT20, the virtual edition of the IFT Annual Meeting ...
(Date:7/1/2020)... ... July 01, 2020 , ... Cure Glioblastoma, ... glioblastoma—the most common and aggressive adult brain cancer—announced today the appointments of its ... are charged with supporting the organization’s initiatives and overall vision. , "Senior Fellows ...
Breaking Biology News(10 mins):
(Date:7/1/2020)... ... June 30, 2020 , ... ... data insights, today announced that the launch of a new clinical ... data about the tumor microenvironment (TME). , “Flagship’s TissueInsight is a service ...
(Date:6/28/2020)... ... June 25, 2020 , ... ... develop a vaccine or drug treatment. In an effort to better understand the ... released the world’s largest imaging dataset portraying therapeutic compound effects from over 1,600 ...
(Date:6/28/2020)... ... June 26, 2020 , ... The Security ... announced its strong opposition to the recently introduced bicameral Facial Recognition and ... on most federal use of nearly all biometric and related image analytics technologies, ...
(Date:6/23/2020)... ... 2020 , ... DeCurtis Corporation, the premier provider of location ... has been appointed CEO and President. Founder and former CEO, David DeCurtis, will ... Corporation has been on an incredible journey for the last twenty years, and ...
Breaking Biology Technology:
Cached News: