HOME >> BIOLOGY >> NEWS
African-American women less likely to undergo genetic testing than white women

There are large racial disparities in the use of genetic testing for breast and ovarian cancer, according to a study in the April 13 issue of JAMA.

Mutations in the genes BRCA1 or BRCA2 confer a significantly increased risk of breast and ovarian cancer, according to background information in the article. Women with a BRCA1/2 mutation have a lifetime breast cancer risk of 50 percent to 85 percent and a lifetime ovarian cancer risk of 14 percent to 40 percent. Testing for mutations in BRCA1/2 can provide individual information about breast and ovarian cancer risk that may affect decisions about prophylactic surgery, chemoprevention, and screening. Although clinical testing for BRCA1/2 mutations became available in 1996, relatively little is known about the determinants of testing use in the general population, including potential racial differences in utilization.

Katrina Armstrong, M.D., M.S.C.E., of the University of Pennsylvania School of Medicine, Philadelphia, and colleagues conducted a study to assess the association between race and use of genetic counseling for BRCA1/2 testing among women at risk of carrying a BRCA1/2 mutation and to evaluate the potential contributions of cancer risk perception and worry, socioeconomic characteristics and attitudes about genetic testing.

The study, conducted from December 1999 to August 2003, included 408 women with a family history of breast or ovarian cancer, of whom 217 underwent genetic counseling for BRCA1/2 testing (cases) and 191 women did not (controls).

The researchers found that "African American women with a family history of breast or ovarian cancer are much less likely [78 percent less likely] to undergo genetic counseling for BRCA1/2 testing than are white women with a family history of breast or ovarian cancer. Furthermore, this racial disparity is not explained by differences in the probability of carrying a BRCA1/2 mutation, socioeconomic status, cancer risk perception and wo
'"/>

Contact: Olivia Fermano
215-349-5653
JAMA and Archives Journals
12-Apr-2005


Page: 1 2 3

Related biology news :

1. New clue why MS affects African-Americans differently than Caucasians
2. Slow wave activity during sleep is lower in African-Americans than Caucasians
3. OSA symptoms more common among African-American women than Caucasians
4. Survey finds perceived risk of recurrence low in African-American breast cancer survivors
5. African-Americans at increased risk for earlier preterm births
6. Missouris African-American mothers more likely to deliver prematurely
7. African-Americans with prostate cancer more likely to have family history of prostate, breast cancer
8. Genetic variant is associated with higher rate of premature delivery in African-American women
9. Faulty cell cycle checkpoints linked to lung cancer risk in African-Americans
10. Breast cancer risk increased for African-Americans with mitochondrial DNA variant
11. NJIT ranked 9th in the nation for graduating African-American engineers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/29/2016)... RATON, Florida , March 29, 2016 ... or the "Company") LegacyXChange "LEGX" and SelectaDNA/CSI Protect are ... DNA in ink used in a variety of writing ... theft. Buyers of originally created collectibles from athletes on ... through forensic analysis of the DNA. ...
(Date:3/18/2016)... 18, 2016 --> ... ICT, Manned & Unmanned Vehicles, Physical infrastructure and Perimeter Surveillance ... in the border security market and the continuing migration crisis ... Europe has led visiongain to publish this ... --> defence & security companies in the ...
(Date:3/14/2016)... , Allemagne, March 14, 2016 ... ) - --> - Renvoi : image ... --> --> ... biométriques, fournit de nouveaux lecteurs d,empreintes digitales pour ... de DERMALOG sera utilisé pour produire des cartes ...
Breaking Biology News(10 mins):
(Date:5/3/2016)... May 3, 2016 - And ... and Producers of Those Competitor Biologics  - ... Activities and Prospects ,  Who are the ... And what are their sales potentials? Discover, in our ... results, trends, opportunities and revenue forecasting. ...
(Date:5/2/2016)... (PRWEB) , ... May 02, 2016 , ... ... with its clients in mind, the fresh look and added functionality give the ... “Recent years have seen a dynamic shift in agriculture – from precision farming ...
(Date:4/29/2016)... ... April 29, 2016 , ... Amendia, ... spinal surgical procedures, today announced the completion of a significant transaction and partnership ... and future customers and partners. Kohlberg & Company, L.L.C. (“Kohlberg”), a leading ...
(Date:4/29/2016)... Elekta is pleased to announce ... industry-leading treatment planning software, is available for clinical release. ... version 5.11 provides significant performance speed enhancements over ... to four times faster than in previous versions of ... standard Monte Carlo algorithm, users ...
Breaking Biology Technology:
Cached News: