HOME >> BIOLOGY >> NEWS
African-American women less likely to undergo genetic testing than white women

There are large racial disparities in the use of genetic testing for breast and ovarian cancer, according to a study in the April 13 issue of JAMA.

Mutations in the genes BRCA1 or BRCA2 confer a significantly increased risk of breast and ovarian cancer, according to background information in the article. Women with a BRCA1/2 mutation have a lifetime breast cancer risk of 50 percent to 85 percent and a lifetime ovarian cancer risk of 14 percent to 40 percent. Testing for mutations in BRCA1/2 can provide individual information about breast and ovarian cancer risk that may affect decisions about prophylactic surgery, chemoprevention, and screening. Although clinical testing for BRCA1/2 mutations became available in 1996, relatively little is known about the determinants of testing use in the general population, including potential racial differences in utilization.

Katrina Armstrong, M.D., M.S.C.E., of the University of Pennsylvania School of Medicine, Philadelphia, and colleagues conducted a study to assess the association between race and use of genetic counseling for BRCA1/2 testing among women at risk of carrying a BRCA1/2 mutation and to evaluate the potential contributions of cancer risk perception and worry, socioeconomic characteristics and attitudes about genetic testing.

The study, conducted from December 1999 to August 2003, included 408 women with a family history of breast or ovarian cancer, of whom 217 underwent genetic counseling for BRCA1/2 testing (cases) and 191 women did not (controls).

The researchers found that "African American women with a family history of breast or ovarian cancer are much less likely [78 percent less likely] to undergo genetic counseling for BRCA1/2 testing than are white women with a family history of breast or ovarian cancer. Furthermore, this racial disparity is not explained by differences in the probability of carrying a BRCA1/2 mutation, socioeconomic status, cancer risk perception and wo
'"/>

Contact: Olivia Fermano
215-349-5653
JAMA and Archives Journals
12-Apr-2005


Page: 1 2 3

Related biology news :

1. New clue why MS affects African-Americans differently than Caucasians
2. Slow wave activity during sleep is lower in African-Americans than Caucasians
3. OSA symptoms more common among African-American women than Caucasians
4. Survey finds perceived risk of recurrence low in African-American breast cancer survivors
5. African-Americans at increased risk for earlier preterm births
6. Missouris African-American mothers more likely to deliver prematurely
7. African-Americans with prostate cancer more likely to have family history of prostate, breast cancer
8. Genetic variant is associated with higher rate of premature delivery in African-American women
9. Faulty cell cycle checkpoints linked to lung cancer risk in African-Americans
10. Breast cancer risk increased for African-Americans with mitochondrial DNA variant
11. NJIT ranked 9th in the nation for graduating African-American engineers

Post Your Comments:
(Date:8/20/2015)... The wearable technology market has traditionally ... healthy. However, wearable technology has the potential to ... improve diagnostic capabilities and therapeutic outcomes. Today, Leaf ... Technologies Conference 2015 , where Barrett Larson ... healthcare.    "Over the past decade, ...
(Date:8/20/2015)... ., Aug. 20, 2015 NXT-ID, Inc. ... biometric authentication company focused on the growing mobile commerce ... it has joined The Smart Card Alliance and the ... Card Alliance and the Smart Card Alliance Latin America ... to industry peers and thought leaders promoting adoption of ...
(Date:8/18/2015)... , Aug. 18, 2015  Navitas today ... contributor to the Submission Content Management webinar ... a non-profit forum. Dedicated to the Implementation of ... neutral platform for industry, vendors, health authorities, ... and work towards a standard method of ...
Breaking Biology News(10 mins):Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 2Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 3NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 2NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 3NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 4Navitas, a Key Contributor in IRISS Forum Webinar 2Navitas, a Key Contributor in IRISS Forum Webinar 3
(Date:9/2/2015)... ... ... Temarry Recycling's new $100,000 waste to energy capital project ... to contribute to the sustainability of our natural resources. , Waste to Energy ... operating at their Mexico facility, Recicladora Temarry, for the last 7 years. While ...
(Date:9/2/2015)... ... September 02, 2015 , ... Genedata, a leading provider of ... Genedata Screener ® version 13.0 at ELRIG Drug Discovery 2015. This latest version ... set of new capabilities. Screener now supports High Throughput Flow Cytometry (HT-Flow) and ...
(Date:9/1/2015)... Blythewood, South Carolina (PRWEB) , ... September 02, 2015 , ... ... solutions, has released new features to its eCommerce site Spirax Sarco Anytime. This ... , Why wait to place your next order? Log on to Spirax ...
(Date:9/1/2015)... N.J. , Sept. 1, 2015  ContraVir Pharmaceuticals, ... on the development and commercialization of targeted antiviral therapies, ... & Renshaw 17 th Annual Global Investment Conference ... place September 8-10, 2015 at The St. Regis Hotel ... James Sapirstein , Chief Executive Officer, ...
Breaking Biology Technology:Temarry Recycling’s New $100,000 Waste to Energy Renovation 2New Genedata Screener 13.0 with Support for High Throughput Flow Cytometry and DMPK Unveiled at ELRIG 2New Genedata Screener 13.0 with Support for High Throughput Flow Cytometry and DMPK Unveiled at ELRIG 3New Genedata Screener 13.0 with Support for High Throughput Flow Cytometry and DMPK Unveiled at ELRIG 4Spirax Sarco Announces New Features to Anytime Platform 2ContraVir to Present at Rodman & Renshaw 17th Annual Global Investment Conference 2
Cached News: