HOME >> BIOLOGY >> NEWS
Alcohol-induced bone disease

Chronic and heavy alcohol consumption is known to contribute to low bone mass, decreased bone formation, an increased incidence of fractures, and delays in fracture healing. A review of human, animal and cell-culture studies of alcohol's detrimental effects on bone has determined that osteoblast development and function are particularly at risk. The review is published in the December issue of Alcoholism: Clinical & Experimental Research.

"The maintenance of healthy bone in human adults occurs through a process called 'bone remodeling,'" said Dennis A. Chakkalakal, research scientist at the Omaha Veterans Affairs Medical Center, associate professor in the department of surgery at Creighton University, and sole author of the review. "At any given time during adult life, and in various parts of the skeleton, small portions of the 'old bone' are removed by cells called 'osteoclasts,' and new bone is formed by cells called 'osteoblasts.' In a healthy person, the two activities are in balance so that there is no net loss of bone."

However, chronic and heavy drinking can disrupt the balance by suppressing new bone formation. "The empty space created by normal bone-removing activity is inadequately filled by newly formed bone," said Chakkalakal. "This process continues at other skeletal sites during the next remodeling cycle. The cumulative effect of this process during several remodeling cycles is manifested as measurable bone loss over a period of just a few years."

"Many people know about alcohol's effects on the liver and the damage it can cause to this organ after years of heavy drinking," said Terrence M. Donohue, Jr., VA Research Career Scientist at the Omaha VA Medical Center and professor of internal medicine at the University of Nebraska Medical Center. "Considerably fewer people know about alcohol-induced bone disease."

Key highlights of the review include:

  • "Alcohol-induced bone disease" refers t
    '"/>



  • 14-Dec-2005


    Page: 1 2 3 4

    Related biology news :

    1. Gilbert Foundation and American Fed for Aging Research award grants on Alzheimers disease
    2. Antioxidant overload may underlie a heritable human disease
    3. Female gender provides an advantage in renal diseases
    4. The female advantage in kidney disease does not extend to diabetic women
    5. Link between sunspots, rain helps predict disease in east Africa
    6. Cornell scientists link E. coli bacteria to Crohns disease
    7. Taking a supplement of glycine helps prevent degenerative diseases such as arthrosis or osteoporosis
    8. Link identified between Alzheimers disease and glaucoma
    9. Huntingtons disease study shows animal models on target
    10. Geisinger scientist seeks cure for Lou Gehrigs disease, creating device to find treatment
    11. News conference on plant diseases and issues important to California

    Post Your Comments:
    *Name:
    *Comment:
    *Email:


    (Date:7/2/2020)... Calif. (PRWEB) , ... July 01, 2020 , ... ... company, presented its phase 1a findings of Neihulizumab, a biologic for the treatment ... in June 2020. Led by hemato-oncologist Dr. Paul J Martin of the Fred ...
    (Date:7/1/2020)... ... July 01, 2020 , ... Cure Glioblastoma, a registered ... common and aggressive adult brain cancer—announced today the appointments of its first Senior ... with supporting the organization’s initiatives and overall vision. , "Senior Fellows are more ...
    (Date:6/25/2020)... (PRWEB) , ... June 24, 2020 , ... ... cloud-based enterprise software and software-driven clinical data services that accelerate drug development, is ... low-dose selinexor, an XPO1 inhibitor, in hospitalized patients with severe COVID-19. This is ...
    Breaking Biology News(10 mins):
    (Date:7/10/2020)... Va. (PRWEB) , ... July 08, 2020 , ... ... testing services and products, announces a significant expansion of laboratory operations through its ... collection for agencies implementing testing programs. , Bode-CARES provides a ...
    (Date:7/10/2020)... LEXINGTON, Mass. (PRWEB) , ... July 09, 2020 ... ... novel approaches to cell therapy, today announced the hiring of Allen R. Nissenson, ... executive team and oversee the clinical development of Sentien’s lead product, SBI-101. ...
    (Date:7/1/2020)... ... June 29, 2020 , ... ... date growth of 40% in 2020, despite many obstacles created as a result ... to increase revenue for its partnered medical practices and medical manufacturers by expanding ...
    (Date:6/28/2020)... ... 25, 2020 , ... The Indoor Lab, a leading provider of sensor solutions ... all types to ensure cleanliness, distancing and occupancy with its patent pending WipeAway™ technology ... business will provide a health performance index system that scores all aspects of compliance ...
    Breaking Biology Technology:
    Cached News: