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American Chemical Society's Weekly PressPac -- May 30, 2007

the blood-brain barrier (BBB) is a tightly knit layer of cells lining the 400 miles of blood vessels in the brain. Intended to protect delicate nerve cells from potentially toxic compounds in the blood, and assure a steady-state chemical environment, the BBB also prevents most actual and would- be drugs from entering the brain.

In doing so, the BBB frustrates efforts by scientists to develop new drugs that could benefit millions of people with clinical depression, stroke, Parkinson's disease, and a range of other conditions. The article describes research efforts to develop medications that are better at penetrating the barrier.

ARTICLE # 5 EMBARGOED FOR 9 A.M., EASTERN TIME, June 4, 2007
"Brain Barricade: Tackling the grueling challenge of getting brain therapies across the blood brain barrier"

This story will be available on June 4 at http://pubs.acs.org/cen/science/85/8523sci1.html

FOR ADVANCE INFORMATION, CONTACT:
Michael Bernstein
ACS News Service
Phone: 202-872-6042
Fax: 202-872-4370
Email: m_bernstein@acs.org

Journalists' Resources

General Chemistry Glossary http://antoine.frostburg.edu/chem/senese/101/glossary.shtml

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Forensic Science

Concise summaries of articles on forensic science published from 2005-2006 in a dozen major journals, courtesy of ACS' Analytical Chemistry

http://pubs.acs.org/cgi-bin/sample.cgi/ancham/asap/html/ac070871s.html


Contact: Michael Woods
m_woods@acs.org
202-872-4400
American Chemical Society
4-Jun-2007


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