HOME >> BIOLOGY >> NEWS
Animal experiments more stressful than previously recognized

WASHINGTON--Mice, rabbits, rats, beagles, geese, and other animals all show measurable physiological stress responses to routine laboratory procedures that have been up until now viewed as relatively benign. The findings come in a new report published in Contemporary Topics in Laboratory Animal Science, based on an extensive review of the scientific literature by ethologist Jonathan Balcombe, Ph.D., of Physicians Committee for Responsible Medicine (PCRM). For example, a mouse who is picked up and briefly held experiences several physiological reactions. As stress-response hormones flood the bloodstream, the mouse exhibits a racing pulse and a spike in blood pressure. These symptoms can persist for up to an hour after each event. Immune response is also affected. In rats and mice, the growth of tumors is strongly influenced by how much the animals are handled.

Dr. Balcombe's paper appears in the journal's current issue, Autumn 2004, available mid-December.

Until now, humane concerns focused mainly on the experiments themselves. The new findings suggest that routine procedures, such as blood draws and use of stomach tubes, are terrifying for animals. "In essence, there is no such thing as a humane animal experiment," says Dr. Balcombe. "Fear or panic ensues when the animal is touched or stuck with a needle."

The paper, a review of 80 previously published studies, is titled, "Laboratory Routines Cause Animal Stress," and focuses on three routine procedures: handling, blood collection and force-feeding. Independent of the invasive experiments themselves, these daily routines can cause an animal to experience elevated bloodstream concentrations of corticosterone, prolactin, glucose, and epinephrine, all indicators of stress. Impaired immune response has also been recorded in animals after anxiety-producing contact with lab personnel.

"Research on tumor development, immune function, endocrine and cardiovascular disorders
'"/>

Contact: Jeanne Stuart McVey
jeannem@pcrm.org
202-686-2210 x316
Physicians Committee for Responsible Medicine
28-Dec-2004


Page: 1 2

Related biology news :

1. Animal studies in the land of the midnight sun illuminate biological clocks
2. Animal testing alternative has ticks trembling at the knees
3. Animals resistant to drunken behavior offer clues to alcoholisms roots
4. Animal physiology conference sheds light on human physiology
5. Koshland Science Museum Program: Animals and their habitat
6. Science Conference Innovations in Bioscience for Animal and Human Health
7. Animal brains hard-wired to recognize predators foot movements, Queens study suggests
8. National Academies Advisory: April 10 Meeting on Distress in Lab Animals
9. Animals can change genes quickly to keep up with viral ingenuity
10. Animal model of Parkinsons disease reveals striking sensitivity to common environmental toxins
11. Animals warn of human health hazards in new Canary Database

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/30/2020)... ... May 29, 2020 , ... ... transformation for enterprises globally, has collaborated with EchoNous Inc. to develop the cloud-based ... can measure systolic heart function, which has been clinically tested versus expert measurements, ...
(Date:5/26/2020)... ... May 26, 2020 , ... ... solutions for biopharmaceutical R&D, today announced that Gritstone Oncology, Inc., a clinical-stage ... bispecific T cell engagers and TCR-based therapeutics, has implemented Genedata Biologics ...
(Date:5/21/2020)... ... 2020 , ... Law Enforcement has always been a highly stressful career – ... of these men and women put them constantly in harm’s way both from the ... have always had to face very high daily stress. Now, COVID-19 introduces another even ...
Breaking Biology News(10 mins):
(Date:7/7/2020)... ... July 06, 2020 , ... ... from Roche, Eli Lilly, Bristol-Myers Squibb, the University of Chicago, Massachusetts General Hospital, ... has hosted an elite awards program, highlighting outstanding examples of how technology innovations ...
(Date:6/28/2020)... ... June 25, 2020 , ... ... to develop a vaccine or drug treatment. In an effort to better understand ... publicly released the world’s largest imaging dataset portraying therapeutic compound effects from over ...
(Date:6/23/2020)... , ... June 22, 2020 , ... ... offering an Amniosomes special offer. This includes buy three, get the fourth unit ... (888) 568-6909. , Amniotic derived exosomes, known as exosomes, have been a game ...
(Date:6/11/2020)... ... June 09, 2020 , ... ... of a Small Business Innovation Research (SBIR) program funded by the National Institute ... Toxin Detection in the Field”. The project’s goal was to engineer and develop ...
Breaking Biology Technology:
Cached News: