Animal study: Compounds in cranberries may have heart-healthy effects

MADISON - Compounds that occur naturally in cranberries may be good for the heart, researchers at the University of Wisconsin-Madison have found.

Early results from studies indicate that feeding cranberry juice powder seems to relax and open blood vessels in pigs that are genetically susceptible to developing atherosclerosis, or clogged arteries. Kris Kruse-Elliott, a veterinary anesthesiologist at the UW-Madison School of Veterinary Medicine, presented her results at the American Physiological Society's annual meeting in San Diego in April.

She and co-researcher Jess Reed, a nutritionist in the Department of Animal Sciences, set out to evaluate various whole foods that contain antioxidants, flavonoids and polyphenols, all compounds that may protect against heart disease. Cranberries contain all three, so they fed cranberry juice powder to pigs that were genetically predisposed to develop high cholesterol and atherosclerosis, just as some humans are.

"When these pigs were fed cranberry juice powder made from whole cranberries for six months, their vessels acted more like normal pigs," Kruse-Elliott says, meaning that the pigs' blood vessels relaxed and opened more.

Abnormal blood vessel function is an important component of heart disease. Finding ways to improve vessel function in patients with high cholesterol and atherosclerosis is critical to helping protect these patients from consequences such as heart attack or stroke.

"The next step is to determine what specific components of cranberries are most important to the improvements in vascular function that we observed, exactly how they modify blood vessel relaxation, and how they can be most easily consumed as part of the diet," Kruse-Elliott says. That last factor may be key. While pigs may not mind the intense tartness of concentrated cranberries, someone will need to make cranberry juice powder palatable to people before the next "heart-protection" diet is born.


Contact: Tania Banak
University of Wisconsin-Madison

Page: 1

Related biology news :

1. Animal studies in the land of the midnight sun illuminate biological clocks
2. Animal testing alternative has ticks trembling at the knees
3. Animals resistant to drunken behavior offer clues to alcoholisms roots
4. Animal physiology conference sheds light on human physiology
5. Koshland Science Museum Program: Animals and their habitat
6. Science Conference Innovations in Bioscience for Animal and Human Health
7. Animal brains hard-wired to recognize predators foot movements, Queens study suggests
8. National Academies Advisory: April 10 Meeting on Distress in Lab Animals
9. Animals can change genes quickly to keep up with viral ingenuity
10. Animal model of Parkinsons disease reveals striking sensitivity to common environmental toxins
11. Animals warn of human health hazards in new Canary Database

Post Your Comments:

(Date:6/21/2016)... 21, 2016 NuData Security announced today that ... of principal product architect and that Jon ... customer development. Both will report directly to ... moves reflect NuData,s strategic growth in its product ... customer demand and customer focus values. ...
(Date:6/16/2016)... FRANCISCO , June 16, 2016 ... size is expected to reach USD 1.83 ... by Grand View Research, Inc. Technological proliferation and ... banking applications are expected to drive the market ... ) , The development of advanced ...
(Date:6/9/2016)... an innovation leader in attendance control systems is proud to announce the introduction of ... make sure the right employees are actually signing in, and to even control the ... ... ... ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... 2016 /PRNewswire/ - BIOREM Inc. (TSX-V: BRM) ("Biorem" or "the ... major shareholders, Clean Technology Fund I, LP and Clean ... based venture capital funds which together hold approximately ... fully diluted, as converted basis), that they have entered ... equity holdings in Biorem to TUS Holdings Co. Ltd. ...
(Date:6/27/2016)... N.C. (PRWEB) , ... June 27, 2016 , ... ... commercial operations for Amgen, will join the faculty of the University of ... as adjunct professor of strategy and entrepreneurship at UNC Kenan-Flagler, with a focus ...
(Date:6/24/2016)... , ... June 24, 2016 , ... While the majority ... as the Cary 5000 and the 6000i models are higher end machines that use ... height of the spectrophotometer’s light beam from the bottom of the cuvette holder. ...
(Date:6/23/2016)... /PRNewswire/ - FACIT has announced the creation of ... company, Propellon Therapeutics Inc. ("Propellon" or "the Company"), ... portfolio of first-in-class WDR5 inhibitors for the treatment ... represent an exciting class of therapies, possessing the ... cancer patients. Substantial advances have been achieved with ...
Breaking Biology Technology:
Cached News: