HOME >> BIOLOGY >> NEWS
Anti-fungal drug kills TB bug

Scientists hoping to find new treatments for one of the worlds most deadly infectious diseases say drugs used to treat common fungal infections may provide the answer.

Tuberculosis, or TB, is a highly contagious disease of the lungs that was thought to have been virtually eliminated by the 1960s, but is now resurgent and kills nearly two million people worldwide every year. New infections are occurring at a rate of one per second.

Of equal concern is the dramatic rise in the incidence of new strains of TB that are resistant to traditional antibiotics. As a result, the World Health Organisation, the Bill Gates Foundation and the European Union have all launched initiatives to tackle the problem.

Now, biologists at The University of Manchester have shown that chemicals called azoles the active agent in many antifungal drugs kill the TB bacteria, and could be effective in tackling the emerging drug-resistant strains.

"TB is back with a vengeance with a third of the worlds population currently infected," said Professor Andrew Munro, who led the research in Manchesters Faculty of Life Sciences.

"The bacterium survives the initial attack by the bodys immune system and then lies dormant, usually in the lungs, waiting for any sign of weakness, such as a secondary infection. Its resurgence over the last 20 years has been closely associated with the AIDS epidemic, which destroys the human immune system and has allowed TB to get a grip once again."

London is the TB capital of Europe, although most large cities here and in North America have seen rapid increases in the number of TB infections. However, the problem is most acute in Africa and Asia where HIV/AIDS is also most prolific and a shortage of traditional TB medicines and problems with patient compliance has led to the emergence of drug-resistant strains of the disease.

"There were only ever a limited number of drugs that were effective against TB
'"/>

Contact: Aeron Haworth
aeron.haworth@manchester.ac.uk
44-161-275-8383
University of Manchester
12-Mar-2007


Page: 1 2 3

Related biology news :

1. Anti-fungal drug may help treat cancer
2. Fat kills cancer
3. DNA analysis suggests under-reported kills of threatened whales
4. Ebola-outbreak kills 5000 gorillas
5. HIV-1 kills immune cells in the gut that may never bounce back
6. Scientists design a PSA-activated protoxin that kills prostate cancer
7. The LouseBuster kills
8. Experimental RNA-based drug kills prostate cancer cells effectively and safely
9. Newly discovered protein kills anthrax bacteria by exploding their cell walls
10. No place like home: Ant navigation skills used in robot navigation
11. New research shows bats have complex skills to deal with clutter

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... , April 5, 2017  The Allen Institute for ... Cell Explorer: a one-of-a-kind portal and dynamic digital window ... imaging data, the first application of deep learning to ... stem cell lines and a growing suite of powerful ... for these and future publicly available resources created and ...
(Date:3/30/2017)... March 30, 2017  On April 6-7, 2017, Sequencing.com ... Genome hackathon at Microsoft,s headquarters in ... will focus on developing health and wellness apps that ... Hack the Genome is the first hackathon for ... world,s largest companies in the genomics, tech and health ...
(Date:3/27/2017)... 27, 2017  Catholic Health Services (CHS) has ... Society (HIMSS) Analytics for achieving Stage 6 on ... . In addition, CHS previously earned a place ... an electronic medical record (EMR). "HIMSS ... of EMR usage in an outpatient setting.  This ...
Breaking Biology News(10 mins):
(Date:6/27/2017)... ... 2017 , ... Indiana-based Xylogenics announced today the release of ... The efficiencies created by the newest strain design will have an immediate ... wherein individual production plants are planning to invest upwards of $350 million annually ...
(Date:6/26/2017)... (PRWEB) , ... June 26, 2017 , ... ... that Melissa Kirkegaard, the former Associate Director of Product Development R&D at Allergan ... and pharmaceutical products at both start-up and established biopharma companies, has joined the ...
(Date:6/26/2017)... ... 26, 2017 , ... The Workgroup for Electronic Data Interchange (WEDI) , ... in healthcare information exchange and a statutory advisor to the U.S. Department of Health ... Office of the National Coordinator for Health Information Technology, will deliver the keynote at ...
(Date:6/23/2017)... ... June 23, 2017 , ... Biova, LLC., the leader in water ... Board of Directors. Dr. Henig will bring a wealth of scientific experience in the ... the Chief Technical and Scientific Officer of four major global companies in the last ...
Breaking Biology Technology:
Cached News: