HOME >> BIOLOGY >> NEWS
Anti-wrinkle compound causes pathological reaction in skin cells

Quebec City, April 11, 2007 -- Researchers from Universit Lavals Faculty of Medicine have discovered that a compound commonly used in many antiwrinkle products causes a pathological reaction in skin cells. Guillaume Morissette, Lucie Germain, and Franois Marceau present their conclusions about the mode of action of this substancecalled DMAEin the latest edition of the British Journal of Dermatology.

DMAE (2-dimethylaminoethanol) is used in many antiwrinkle products dubbed "instant anti-aging face-lifts." This compound, as well as other chemically similar ones, are also found in cosmetics, creams, lipsticks, shampoos, soaps, and baby lotions, although the way they work is not yet understood.

In vitro tests conducted by Dr. Marceaus team revealed that the application of DMAE induces a quick and spectacular swelling of skin cell vacuoles called fibroblasts, which act as reservoirs and interface between the inside and the outside of the cell.

In the hours following the application of DMAE, the researchers observed an important slowing down of cell divisionsometimes coming to a complete stop, the inhibition of certain metabolic reactions, and the death of a significant percentage of fibroblasts. The mortality rate of fibroblasts, which varied according to DMAE concentration, was above 25% after 24 hours in the case of a concentration similar to the one resulting from normal use of an antiwrinkle cream. The thickening of the skin induced by the pathological swelling of the fibroblasts would explain the antiwrinkle effect of DMAE, according to the researchers.

"Even though DMAE is similar to medication, there is very little scientific documentation about its pharmacological and toxicological effects," explains Dr. Marceau, who stresses his goal is not to condemn the use of this compound. "Were not saying DMAE is dangerous to people exposed to it, but our results indicate its time to begin serious research to determine whether or n
'"/>

Contact: Jean-Franois Hupp
jean-francois.huppe@dap.ulaval.ca
418-656-7785
Universit Laval
11-Apr-2007


Page: 1 2

Related biology news :

1. A compound from olive-pomace oil gets 80 percent slowing down of HIV spread
2. New compound effectively treats fungal infections
3. Natural compound and exercise boost memory in mice
4. Lipoic acid explored as anti-aging compound
5. Pharmaceutical compounds found in nations fresh water
6. Chinese medicinal compound stops formation of cysts in polycystic kidney disease in lab
7. EPA selects Phylonix to screen compound library in zebrafish
8. Marine moss reveals clues to anticancer compound
9. New compound prevents alcoholic behavior, relapse in animals by blocking stress response
10. Light-activated compound silences nerves, may one day help epileptics
11. New compound isolated from Madagascan plant shows activity against malaria

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/13/2017)... According to a new market research report "Consumer IAM Market by ... Service, Authentication Type, Deployment Mode, Vertical, and Region - Global Forecast to ... USD 14.30 Billion in 2017 to USD 31.75 Billion by 2022, at ... ... MarketsandMarkets Logo ...
(Date:4/11/2017)... Research and Markets has announced the addition ... their offering. ... tracking market to grow at a CAGR of 30.37% during the ... 2017-2021, has been prepared based on an in-depth market analysis with ... its growth prospects over the coming years. The report also includes ...
(Date:4/11/2017)... NXT-ID, Inc. (NASDAQ:   NXTD ) ("NXT-ID" or ... independent Directors Mr. Robin D. Richards and Mr. ... the company,s corporate governance and expertise. ... Gino Pereira , Chief Executive Officer said," ... and benefiting from their considerable expertise as we move forward ...
Breaking Biology News(10 mins):
(Date:4/27/2017)... and RESEARCH TRIANGLE PARK, N.C. ... (NASDAQ: UTHR ) today announced that its ... $250 million of the company,s common stock. This program ... December 31, 2017. Purchases may be made in the ... transactions from time to time as determined by United ...
(Date:4/27/2017)... ... April 27, 2017 , ... Mitotech S.A, a Luxembourg ... Hereditary Optic Neuropathy (LHON) patients. LHON is a rare devastating genetic disease that leads ... eye drops in a group of 20 patients carrying 11778, 14484 and 3460 mutations ...
(Date:4/27/2017)... Linda, Ca (PRWEB) , ... April 27, 2017 ... ... hear from a practicing internist, who will review how testing for 1,25-Dihydroxyvitamin D ... that prompt ordering of 25-OH-vitamin D and 1,25 dihydroxyvitamin D. , Dr. Gregory ...
(Date:4/27/2017)... ... April 27, 2017 , ... Volunteers supported by ... researchers, engineers, and industry professionals in visiting U.S. Congressional offices in Washington, D.C., ... the world photonics industry. , This year, National Photonics Initiative (NPI) ...
Breaking Biology Technology:
Cached News: