HOME >> BIOLOGY >> NEWS
Are yeast cells bringing us a step closer in treating obesity?

For the first time, researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected with the Catholic University of Leuven have shown clearly that receptors in yeast cells detect and react to nutrients in the cell. The chance is great that this is also the case with human cells. Because about 40% of today's medicines act on receptors in our cells, this research opens new possibilities for the treatment of metabolic disorders such as diabetes and obesity.

Detecting sugars in the cell

Every living thing is composed of cells, which communicate with each other and the external world by means of receptor proteins on the cell membrane. These proteins receive signals from outside the cell by binding themselves with particular substances (such as hormones), which then produces a reaction by the cell to regulate processes internal or external to the cell. A number of medicines play on this cellular operation to produce beneficial responses for our health. Now, for the first time, Katleen Lemaire and her colleagues, under the direction of Johan Thevelein of VIB and the Catholic University of Leuven, have discovered receptor proteins in yeast cells that detect and react to glucose and sucrose.

The detection of glucose, the transport sugar in the blood, is of major importance for all the cells in the body. Glucose is not only absorbed and metabolized by the cells - it also regulates many cellular reactions. When too much or too little glucose is present in the blood - as in diabetes, for example - this process can break down. The discovery that receptor proteins react to sugars like glucose is very important to the search for treatments for metabolic diseases. Indeed, these proteins could be good targets for new medicines to compensate for the surplus or shortage of a particular sugar.

Yeast as model for humans

The VIB scientists are conducting their research on yeast proteins. It often turns out t
'"/>

Contact: Sooike Stoops
sooike.stoops@vib.be
32-9-244-6611
VIB, Flanders Interuniversity Institute of Biotechnology
21-Oct-2004


Page: 1 2

Related biology news :

1. Tiny tweezers and yeast help St. Jude show how cancer drug works
2. Hives ferment a yeasty brew, attract beetle pest
3. Vitamin extends life in yeast, Dartmouth Medical School researchers find
4. Protein structures for the entire yeast proteome
5. Primitive yeast yields secrets of human cholesterol and drug metabolism
6. MIT: Engineered yeast speeds ethanol production
7. Engineered yeast speeds ethanol production
8. From a lowly yeast, researchers divine a clue to human disease
9. Potassium limitation, ammonium toxicity and amino acid excretion in yeast
10. Dartmouth and GlycoFi report full humanization of therapeutic proteins from yeast
11. GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Are yeast cells bringing step closer treating obesity

(Date:3/23/2015)... Mass , March 23, 2015 SoundView Technology ... of NXT-ID,s (NASDAQ: NXTD ) Wocket smart wallet. SoundView was ... user feedback on their experience with the Wocket in multiple ... at CVS, Whole Foods and other retailers, making both debit ... Kris Tuttle also says, "If the company meets their ...
(Date:3/23/2015)... March 23, 2015  In the 2014 fiscal year, ... conviction losses. This figure accounts for a fraction of ... The Nilson Report, exceeds $11 billion globally. The polygraph ... a crime has occurred. Investor Mark Saint Juste ... Joe Paolella partnered to administer the test ...
(Date:3/20/2015)... Research and Markets ( http://www.researchandmarkets.com/research/4stcg3/india_sensors ... "India Sensors Market Forecast and Opportunities 2020" ... market is projected to grow at a CAGR ... automotive, industrial and healthcare sectors are the key ... addition, adoption of MEMS technology in sensors is ...
Breaking Biology News(10 mins):Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3
(Date:4/28/2015)... More than 50% of patients with Parkinson’s ... the course of their disease, and clinicians are challenged ... disease progresses. ReachMD , the 24/7 health education ... series dedicated to PD psychosis, featuring interviews and commentary ... psychiatric conditions. , The new series titled Perspectives ...
(Date:4/28/2015)... York (PRWEB) April 28, 2015 Dr. ... sales, marketing, and customer service operations across the products ... Test , the first and only FDA-cleared test to ... to aid in embryo selection during IVF. , Dr. ... the field of Reproductive Sciences, including both laboratory management ...
(Date:4/27/2015)... , April 27, 2015  For about a ... is their ability to utilize and catabolize glucose ... cancer cells is called the ,Warburg phenomenon", that ... of high oxygen presence, leading to enhanced lactate ... cells still choose glucose fermentation. A variety of ...
(Date:4/27/2015)... , April 27, 2015  Edico Genome today ... geneticists from Harvard and Stanford Universities showed the ... genome sequence with 300x depth of coverage by ... to 60 hours with standard software. ... challenge, especially for individual research and clinical labs, ...
Breaking Biology Technology:ReachMD Launches Series Focusing on Parkinson’s Disease Psychosis 2Progyny Appoints Gary Harton as Group Senior Vice President, Commercial Development 2Study Indicates Cancer Cells Alter Glucose Metabolism to Enhance Energy Production and Cell Growth 2Edico Genome, in Collaboration with Researchers from Harvard and Stanford Universities, Speeds Analysis of Whole Genome Sequence with 300x Depth of Coverage Tenfold 2Edico Genome, in Collaboration with Researchers from Harvard and Stanford Universities, Speeds Analysis of Whole Genome Sequence with 300x Depth of Coverage Tenfold 3
Cached News: