HOME >> BIOLOGY >> NEWS
Are yeast cells bringing us a step closer in treating obesity?

For the first time, researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected with the Catholic University of Leuven have shown clearly that receptors in yeast cells detect and react to nutrients in the cell. The chance is great that this is also the case with human cells. Because about 40% of today's medicines act on receptors in our cells, this research opens new possibilities for the treatment of metabolic disorders such as diabetes and obesity.

Detecting sugars in the cell

Every living thing is composed of cells, which communicate with each other and the external world by means of receptor proteins on the cell membrane. These proteins receive signals from outside the cell by binding themselves with particular substances (such as hormones), which then produces a reaction by the cell to regulate processes internal or external to the cell. A number of medicines play on this cellular operation to produce beneficial responses for our health. Now, for the first time, Katleen Lemaire and her colleagues, under the direction of Johan Thevelein of VIB and the Catholic University of Leuven, have discovered receptor proteins in yeast cells that detect and react to glucose and sucrose.

The detection of glucose, the transport sugar in the blood, is of major importance for all the cells in the body. Glucose is not only absorbed and metabolized by the cells - it also regulates many cellular reactions. When too much or too little glucose is present in the blood - as in diabetes, for example - this process can break down. The discovery that receptor proteins react to sugars like glucose is very important to the search for treatments for metabolic diseases. Indeed, these proteins could be good targets for new medicines to compensate for the surplus or shortage of a particular sugar.

Yeast as model for humans

The VIB scientists are conducting their research on yeast proteins. It often turns out t
'"/>

Contact: Sooike Stoops
sooike.stoops@vib.be
32-9-244-6611
VIB, Flanders Interuniversity Institute of Biotechnology
21-Oct-2004


Page: 1 2

Related biology news :

1. Tiny tweezers and yeast help St. Jude show how cancer drug works
2. Hives ferment a yeasty brew, attract beetle pest
3. Vitamin extends life in yeast, Dartmouth Medical School researchers find
4. Protein structures for the entire yeast proteome
5. Primitive yeast yields secrets of human cholesterol and drug metabolism
6. MIT: Engineered yeast speeds ethanol production
7. Engineered yeast speeds ethanol production
8. From a lowly yeast, researchers divine a clue to human disease
9. Potassium limitation, ammonium toxicity and amino acid excretion in yeast
10. Dartmouth and GlycoFi report full humanization of therapeutic proteins from yeast
11. GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/22/2016)... -- On Monday, the Department of Homeland Security (DHS) ... for the Biometric Exit Program. The Request for Information ... explains that CBP intends to add biometrics to confirm ... States , in order to deter visa overstays, ... Logo - http://photos.prnewswire.com/prnh/20160622/382209LOGO ...
(Date:6/16/2016)... The global Biometric ... USD 1.83 billion by 2024, according to a ... proliferation and increasing demand in commercial buildings, consumer ... the market growth.      (Logo: ... of advanced multimodal techniques for biometric authentication and ...
(Date:6/9/2016)... Paris Police Prefecture ... solution to ensure the safety of people and operations in ... major tournament Teleste, an international technology group specialised ... today that its video security solution will be utilised by ... public safety across the country. The system roll-out is scheduled ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... ... June 24, 2016 , ... While the majority of commercial spectrophotometers ... 5000 and the 6000i models are higher end machines that use the more unconventional ... spectrophotometer’s light beam from the bottom of the cuvette holder. , FireflySci has ...
(Date:6/23/2016)... TORONTO , June 23, 2016 /PRNewswire/ - ... Ontario biotechnology company, Propellon ... the development and commercialization of a portfolio of ... cancers. Epigenetic targets such as WDR5 represent an ... contribute significantly in precision medicine for cancer patients. ...
(Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge (BDC), ... new ways to harness living systems and biotechnology, announced ... (MoMA) in New York City . ... participating students, showcased projects at MoMA,s Celeste Bartos Theater ... Antonelli , MoMA,s senior curator of architecture and design, ...
(Date:6/23/2016)... LOUISVILLE, Ky. , June 23, 2016 /PRNewswire/ ... from two Phase 1 clinical trials of its ... double-blind, placebo-controlled, single and multiple ascending dose studies ... and pharmacodynamics (PD) of subcutaneous injection in healthy ... APL-2 subcutaneously (SC) either as a single dose ...
Breaking Biology Technology:
Cached News: