HOME >> BIOLOGY >> NEWS
Are yeast cells bringing us a step closer in treating obesity?

For the first time, researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected with the Catholic University of Leuven have shown clearly that receptors in yeast cells detect and react to nutrients in the cell. The chance is great that this is also the case with human cells. Because about 40% of today's medicines act on receptors in our cells, this research opens new possibilities for the treatment of metabolic disorders such as diabetes and obesity.

Detecting sugars in the cell

Every living thing is composed of cells, which communicate with each other and the external world by means of receptor proteins on the cell membrane. These proteins receive signals from outside the cell by binding themselves with particular substances (such as hormones), which then produces a reaction by the cell to regulate processes internal or external to the cell. A number of medicines play on this cellular operation to produce beneficial responses for our health. Now, for the first time, Katleen Lemaire and her colleagues, under the direction of Johan Thevelein of VIB and the Catholic University of Leuven, have discovered receptor proteins in yeast cells that detect and react to glucose and sucrose.

The detection of glucose, the transport sugar in the blood, is of major importance for all the cells in the body. Glucose is not only absorbed and metabolized by the cells - it also regulates many cellular reactions. When too much or too little glucose is present in the blood - as in diabetes, for example - this process can break down. The discovery that receptor proteins react to sugars like glucose is very important to the search for treatments for metabolic diseases. Indeed, these proteins could be good targets for new medicines to compensate for the surplus or shortage of a particular sugar.

Yeast as model for humans

The VIB scientists are conducting their research on yeast proteins. It often turns out t
'"/>

Contact: Sooike Stoops
sooike.stoops@vib.be
32-9-244-6611
VIB, Flanders Interuniversity Institute of Biotechnology
21-Oct-2004


Page: 1 2

Related biology news :

1. Tiny tweezers and yeast help St. Jude show how cancer drug works
2. Hives ferment a yeasty brew, attract beetle pest
3. Vitamin extends life in yeast, Dartmouth Medical School researchers find
4. Protein structures for the entire yeast proteome
5. Primitive yeast yields secrets of human cholesterol and drug metabolism
6. MIT: Engineered yeast speeds ethanol production
7. Engineered yeast speeds ethanol production
8. From a lowly yeast, researchers divine a clue to human disease
9. Potassium limitation, ammonium toxicity and amino acid excretion in yeast
10. Dartmouth and GlycoFi report full humanization of therapeutic proteins from yeast
11. GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Are yeast cells bringing step closer treating obesity

(Date:11/5/2014)... professor of biology in the UTSA College of ... nation selected to receive a two-year $300,00 National ... Research (EAGER). The funding supports President Obama,s BRAIN ... create new technology that will demystify complex brain ... in neuroscience are broken into the interactions of ...
(Date:11/4/2014)... SALT LAKE CITY, Nov. 5, 2014 – University of ... uses enzymes to help jet fuel produce electricity without ... can be used to power portable electronics, off-grid power ... appears online today in the American Chemical Society journal ... into electricity through a chemical reaction between a fuel ...
(Date:11/4/2014)... 2014) — Think about the way our bodies are ... cells know that they are supposed to become a ... tissues find the correct place and alignment? Researchers at ... questions. , In a new study, UM researchers describe ... their surrounding neighbors, at the head-trunk region. Their discovery ...
Breaking Biology News(10 mins):UTSA biology professor awarded $300,000 NSF grant for brain research 2UTSA biology professor awarded $300,000 NSF grant for brain research 3Jet-fueled electricity at room temperature 2The inside story: How the brain and skull stay together 2
(Date:11/24/2014)... 2014 The new video, “ ... TOLEDO demonstrates how to reduce the number of ... sample panel design can be complicated, requiring multiple ... against corrosion and deposition. Dedicated single and dual ... of panel space. Additionally, installing and maintaining each ...
(Date:11/22/2014)... During his lifetime Richard L. Sharp was a ... with great people and take risks to achieve success. ... at his extraordinarily courageous attitude when taking on challenges. ... with his death impending—that’s how he continued looking for ... take his life. , Carrying on Sharp’s relentless dream ...
(Date:11/22/2014)... 2014 The “Chiral Chromatography Columns ... Material (Metal, Glass, Plastic), by Application [GC, LC ... Forecast to 2018” analyses and studies the major ... America, Europe, Asia, and Rest of the World. ... figures spread through 135 pages and in-depth TOC ...
(Date:11/21/2014)... Nov. 21, 2014   TRU-D SmartUVC LLC and ... superbug-killing UVC automated disinfection robot, TRU-D SmartUVC, at FIS 2014 ... Nov. 23 to 26 at Stand 23. The ... United Kingdom,s largest infection-related event of its ... to one of the leading events of its type throughout ...
Breaking Biology Technology:New Video Shows How to Simplify Cycle Chemistry Sample Panels to Save Time and Costs 2Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 2Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 3Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 2Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 3Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 4Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 5TRU-D SmartUVC to Showcase Superbug-Killing Robot at FIS 2014 2TRU-D SmartUVC to Showcase Superbug-Killing Robot at FIS 2014 3
Cached News: