HOME >> BIOLOGY >> NEWS
Are yeast cells bringing us a step closer in treating obesity?

For the first time, researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected with the Catholic University of Leuven have shown clearly that receptors in yeast cells detect and react to nutrients in the cell. The chance is great that this is also the case with human cells. Because about 40% of today's medicines act on receptors in our cells, this research opens new possibilities for the treatment of metabolic disorders such as diabetes and obesity.

Detecting sugars in the cell

Every living thing is composed of cells, which communicate with each other and the external world by means of receptor proteins on the cell membrane. These proteins receive signals from outside the cell by binding themselves with particular substances (such as hormones), which then produces a reaction by the cell to regulate processes internal or external to the cell. A number of medicines play on this cellular operation to produce beneficial responses for our health. Now, for the first time, Katleen Lemaire and her colleagues, under the direction of Johan Thevelein of VIB and the Catholic University of Leuven, have discovered receptor proteins in yeast cells that detect and react to glucose and sucrose.

The detection of glucose, the transport sugar in the blood, is of major importance for all the cells in the body. Glucose is not only absorbed and metabolized by the cells - it also regulates many cellular reactions. When too much or too little glucose is present in the blood - as in diabetes, for example - this process can break down. The discovery that receptor proteins react to sugars like glucose is very important to the search for treatments for metabolic diseases. Indeed, these proteins could be good targets for new medicines to compensate for the surplus or shortage of a particular sugar.

Yeast as model for humans

The VIB scientists are conducting their research on yeast proteins. It often turns out t
'"/>

Contact: Sooike Stoops
sooike.stoops@vib.be
32-9-244-6611
VIB, Flanders Interuniversity Institute of Biotechnology
21-Oct-2004


Page: 1 2

Related biology news :

1. Tiny tweezers and yeast help St. Jude show how cancer drug works
2. Hives ferment a yeasty brew, attract beetle pest
3. Vitamin extends life in yeast, Dartmouth Medical School researchers find
4. Protein structures for the entire yeast proteome
5. Primitive yeast yields secrets of human cholesterol and drug metabolism
6. MIT: Engineered yeast speeds ethanol production
7. Engineered yeast speeds ethanol production
8. From a lowly yeast, researchers divine a clue to human disease
9. Potassium limitation, ammonium toxicity and amino acid excretion in yeast
10. Dartmouth and GlycoFi report full humanization of therapeutic proteins from yeast
11. GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... IBM ) is introducing several innovative partner startups at VivaTech ... startups and global businesses, taking place in Paris ... will showcase the solutions they have built with IBM Watson ... France is one of the most dynamic ... in the number of startups created between 2012 and 2015*, ...
(Date:4/24/2017)... 24, 2017 Janice Kephart , ... Identity Strategy Partners, LLP (IdSP) , today issues ... President Trump,s March 6, 2017 Executive Order: ... vetting can be instilled with greater confidence, enabling ... all refugee applications are suspended by until at ...
(Date:4/13/2017)... According to a new market research report "Consumer IAM Market ... Authorization), Service, Authentication Type, Deployment Mode, Vertical, and Region - Global Forecast ... from USD 14.30 Billion in 2017 to USD 31.75 Billion by 2022, ... ... MarketsandMarkets Logo ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... JOHNSTON, Iowa (PRWEB) , ... October 12, 2017 ... ... company based in Vilnius, Lithuania, announced today that they have entered into a ... collaboration is to provide CRISPR researchers with additional tools for gene editing across ...
(Date:10/12/2017)... ... 12, 2017 , ... BioMedGPS announces expanded coverage of SmartTRAK ... module, US Hemostats & Sealants. , SmartTRAK’s US Market for Hemostats and Sealants ... sealants and biologic sealants used in surgical applications. BioMedGPS estimates the market will ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... Rosalind™, the first-ever genomics analysis platform specifically designed for life science researchers ... honor of pioneering researcher Rosalind Franklin, who made a major contribution to ...
(Date:10/11/2017)... ... October 11, 2017 , ... The ... endogenous context, enabling overexpression experiments and avoiding the use of exogenous expression plasmids. ... is transformative for performing systematic gain-of-function studies. , This complement to loss-of-function ...
Breaking Biology Technology:
Cached News: