HOME >> BIOLOGY >> NEWS
Aspirin is safer than warfarin and just as effective for treating blocked arteries in the brain

To reduce the risk of stroke, partial blockage of arteries in the brain (intracranial stenosis) has for decades been treated with drugs such as aspirin and warfarin that reduce blood clotting. However, doctors have never had good evidence for choosing one therapy over the other. Now, results of a double-blind, randomized clinical trial show for the first time that aspirin works as well as warfarin with fewer side effects. The study was funded by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH).

"This trial is good news. A simple low-cost drug works just as well as one that requires complicated and expensive monitoring and dose adjustments," says John R. Marler, M.D., the Associate Director for Clinical Trials at NINDS. The study appears in the March 31, 2005, issue of the New England Journal of Medicine.*

Intracranial stenosis is caused by atherosclerosis -- fatty deposits that build up on the inner walls of the arteries and restrict blood flow. Intracranial stenosis causes about 10 percent of the 900,000 strokes and transient ischemic attacks (TIAs) in the United States each year. TIAs are transient strokes that last only a few minutes and occur when the blood supply to part of the brain is briefly interrupted. People with a stroke or TIA due to intracranial stenosis have a greatly increased risk of a second stroke as much as 15 percent per year. Studies in the 1950s suggested that anticoagulants (a class of drugs that reduce blood clotting), such as warfarin, can reduce the risk of stroke in people with this disease.

In the new study, called the Warfarin Aspirin Symptomatic Intracranial Disease (WASID) trial, investigators at 59 medical centers across the United States, led by Marc I. Chimowitz, M.D., of Emory University in Atlanta, compared warfarin to 1300 milligrams (mg) per day of aspirin in a total of 569 patients for an average of 1.8 years. All of the pat
'"/>

Contact: Natalie Frazin or Paul Girolami
301-496-5924
NIH/National Institute of Neurological Disorders and Stroke
30-Mar-2005


Page: 1 2 3

Related biology news :

1. Aspirin + cholesterol drugs + blood pressure drugs = Less severe strokes
2. Aspirin might prevent Vioxx cardiac damage
3. Decoding mushrooms secrets could combat carbon, find better biofuels and safer soils
4. FSU researchers reap $1-million grant to make medical implants safer
5. Natural polyester makes new sutures stronger, safer
6. Study finds surfing safer than soccer
7. New study finds amniocentesis safer for pregnant women
8. OHSU eye doctor says laser surgery safer than contacts
9. Pregnant drivers, football players safer thanks to a top Virginia Tech researcher
10. New procedure safer for detecting fetal anemia
11. New technique points to safer, more efficient vaccination

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/7/2018)... ... September 05, 2018 , ... Following up on the launch ... year, IPS-Integrated Project Services, LLC and G-CON Manufacturing have successfully designed and delivered ... solution provides a pre-fabricated modular cleanroom infrastructure for the drug manufacturers’ requirements for ...
(Date:8/31/2018)... ... August 30, 2018 , ... CallTower is pleased ... more than 20-years of telecommunications experience and over ten years in executive leadership. Prior ... acquired by CallTower in early 2018. , In this new role, Jason ...
(Date:8/29/2018)... CAMBRIDGE, Mass. (PRWEB) , ... August 28, 2018 ... ... QipWorks, today introduced an annual awards program that recognizes women of excellence in ... recipient. , Sponsored by QipWorks, the Johanna Dwyer Women in IP Award aims ...
Breaking Biology News(10 mins):
(Date:8/29/2018)... ... August 28, 2018 , ... Cognition Corporation ®, a software company ... for NAVIGATE2018 . , Ryan Ward, Director of Engineering at Zimmer Biomet, ... An experienced engineer and manager with Zimmer Biomet for almost 15 years, Mr. Ward ...
(Date:8/26/2018)... ... August 23, 2018 , ... LabRoots , ... from around the world, will host the 4th Annual Microbiology and Immunology Virtual ... and disciplines, encompassing various research areas including medicine, agriculture, and space. , ...
(Date:8/21/2018)... Conn. (PRWEB) , ... August 21, 2018 , ... The ... 40, an annual recognition of the fastest growing technology companies in Connecticut. This year’s ... be held on Wednesday, October 3, at the Connecticut Convention Center in Hartford. A ...
(Date:8/14/2018)... ... August 13, 2018 , ... Labconco Corporation manufactures laboratory equipment, ... In addition, Labconco produces other lab equipment, such as glassware washers and freeze ... and consistency in design and manufacturing. , Through this webinar, which is ...
Breaking Biology Technology:
Cached News: