HOME >> BIOLOGY >> NEWS
Bacteria have their own immune system protecting against outside DNA

m Navarre, a senior fellow at the UW and primary author of the study. "This research gives us an explanation of how pathogenic bacteria have evolved over millions of years."

The researchers also learned that the H-NS protein is able to recognize foreign DNA on the basis of its increased content of adenine and thymine, the building blocks of DNA.

"It has been a great mystery why disease-causing genes of bacteria usually contain more adenine and thymine," said Michael McClelland, professor and director of the Molecular Biology Program at the Kimmel Cancer Center. "Now we know this is because such sequences are easier to recruit and regulate than other DNA."

This research could also have major implications for the biotech industry, which uses bacteria for the production of recombinant proteins for medicine and research. These proteins, such as insulin or human growth hormone, are created when a piece of human DNA corresponding to that protein is introduced into bacteria. The bacteria then reproduce many times over, creating more of the protein each time they reproduce. The proteins are purified out from the bacteria, leaving behind only the useful protein. However, in that process, the yield of some human proteins produced in bacteria can be low. The new research indicates that the H-NS "immune system" may be responsible for interfering with the expression of human genes in bacteria.

"Having a better understanding of this system could help the biotech industry make recombinant proteins more efficiently," said Fang. "More foreign protein can be produced in bacteria that don't have the H-NS molecule."


'"/>

Contact: Justin Reedy
jreedy@u.washington.edu
206-685-0382
University of Washington
8-Jun-2006


Page: 1 2

Related biology news :

1. Bacteria may not hasten death
2. A friendly foe -- Bacteria residing in the gut boost immune response to tumors
3. Bacteria ferry nanoparticles into cells for early diagnosis, treatment
4. Bacteria show promise in fending off global amphibian killer
5. Bacteria control how infectious they become, study finds
6. Better together: Bacterial endosymbionts are essential for the reproduction of a fungus
7. Bacterial response to oxidation studied as toxin barometer
8. Bacteria from patients dental plaque causes ventilator-associated pneumonia
9. Bacterial walls come tumbling down
10. Bacteria could steady buildings against earthquakes
11. Bacteria research offers hope for new vaccine against meningococci

Post Your Comments:
(Date:3/17/2015)...  MecklerMedia Corporation (OTCQX: MECK) announced its ... ever held in New York City ... 2015 at the Javits Convention Center. ... Acorn Product Development; Axis NJ; c-Link Systems; CoroWare; ... NewBotic Corporation; Neya Systems LLC; Reliabotics; RoboKind; RocketFarm ...
(Date:3/12/2015)... FAIRFAX, Va. , March 12, 2015 ... company and a member of the Texas Instruments Design ... Chandrababu Naidu has demonstrated its IriShield USB MK2120U ... iris scanning facility for pension distribution. ... and assembled to be marketed in India ...
(Date:3/12/2015)... 2015 Beta Systems today ... access management (IAM) solution for a fixed price ... System,s new IAM package, customers benefit from the ... multiple IAM implementations across different industries. The new ... as any necessary services and consulting. It spans ...
Breaking Biology News(10 mins):MecklerMedia's RoboUniverse New York Announces Sponsors and Exhibitors, May 11-13, 2015 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 3Beta Systems Fast Forward IAM Available Now: a Standardized IAM Package at a Fixed Price 2
(Date:3/25/2015)... March 25, 2015 /PRNewswire/ - SQI Diagnostics Inc. ("SQI" or ... a result of recent discussions with certain shareholders representing ... the Company, after dealing with certain matters including the ... of shareholders on March 26, 2015 (the "Meeting") it ... of directors will take place when the Meeting reconvenes. ...
(Date:3/25/2015)... Laboratory workers can turn to ... Balances to get best-performing features while still remaining ... from the trusted brand include: , Cole-Parmer ... efficiency by providing a large weighing surface for ... include parts counting, percent weighing, checkweighing, animal/dynamic weighing, ...
(Date:3/25/2015)... CORAL SPRINGS, Fla. , March 25, 2015 ... (HIT) strategy and management consulting firm, has launched ... reference publication to simplify tracking of ePrescribing regulatory ... "The ePrescribing regulatory landscape continues to ... offerings to deliver what the industry, and ultimately ...
(Date:3/25/2015)... LOUIS and the HAGUE, Netherlands ... of two-year results of LES Stimulation therapy for chronic ... the journal Surgery [ Surgery . ... efficacy of its minimally-invasive therapy. The ... average duration of 11 years and taking prescribed daily ...
Breaking Biology Technology:SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 2SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 3SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 4SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 5New Economical Top-Loading and Analytical Symmetry Balances from Cole-Parmer 2Point-of-Care Partners Launches the ePrescribing State Law Capsule 2EndoStim LES Stimulation therapy demonstrates long term safety and efficacy results in treating reflux patients 2EndoStim LES Stimulation therapy demonstrates long term safety and efficacy results in treating reflux patients 3
Cached News: