HOME >> BIOLOGY >> NEWS
Bacteria have their own immune system protecting against outside DNA

m Navarre, a senior fellow at the UW and primary author of the study. "This research gives us an explanation of how pathogenic bacteria have evolved over millions of years."

The researchers also learned that the H-NS protein is able to recognize foreign DNA on the basis of its increased content of adenine and thymine, the building blocks of DNA.

"It has been a great mystery why disease-causing genes of bacteria usually contain more adenine and thymine," said Michael McClelland, professor and director of the Molecular Biology Program at the Kimmel Cancer Center. "Now we know this is because such sequences are easier to recruit and regulate than other DNA."

This research could also have major implications for the biotech industry, which uses bacteria for the production of recombinant proteins for medicine and research. These proteins, such as insulin or human growth hormone, are created when a piece of human DNA corresponding to that protein is introduced into bacteria. The bacteria then reproduce many times over, creating more of the protein each time they reproduce. The proteins are purified out from the bacteria, leaving behind only the useful protein. However, in that process, the yield of some human proteins produced in bacteria can be low. The new research indicates that the H-NS "immune system" may be responsible for interfering with the expression of human genes in bacteria.

"Having a better understanding of this system could help the biotech industry make recombinant proteins more efficiently," said Fang. "More foreign protein can be produced in bacteria that don't have the H-NS molecule."


'"/>

Contact: Justin Reedy
jreedy@u.washington.edu
206-685-0382
University of Washington
8-Jun-2006


Page: 1 2

Related biology news :

1. Bacteria may not hasten death
2. A friendly foe -- Bacteria residing in the gut boost immune response to tumors
3. Bacteria ferry nanoparticles into cells for early diagnosis, treatment
4. Bacteria show promise in fending off global amphibian killer
5. Bacteria control how infectious they become, study finds
6. Better together: Bacterial endosymbionts are essential for the reproduction of a fungus
7. Bacterial response to oxidation studied as toxin barometer
8. Bacteria from patients dental plaque causes ventilator-associated pneumonia
9. Bacterial walls come tumbling down
10. Bacteria could steady buildings against earthquakes
11. Bacteria research offers hope for new vaccine against meningococci

Post Your Comments:
(Date:10/31/2014)... live in Nuristan Province – some 60 years after ... glands are more valuable than gold , Study appears ... , NEW YORK (October 31, 2014) – More ... strange deer with vampire-like fangs still persists in the ... research team led by the Wildlife Conservation Society (WCS), ...
(Date:10/31/2014)... wide part of the electromagnetic spectrum from the infrared ... Sweden. The MAX IV facility presents a range of ... parts in a storage - ring synchrotron system that ... metres. Nevertheless, if these various challenges can be addressed ... source brightness and transverse coherence will be possible. ...
(Date:10/31/2014)... air out of a nagging mystery about the development of ... to why animal species didn,t flourish sooner, once sufficient oxygen ... end of the Proterozoic period, about 800 million years ago ... most researchers think there also was plenty of oxygen? , ... all. , In a study published Oct. 30 in ...
Breaking Biology News(10 mins):Strange, fanged deer persists in Afghanistan 2A new generation of storage -- ring 2Lack of oxygen delayed the rise of animals on Earth 2
(Date:10/31/2014)... 2014 Having access to safe drinking ... battle in many corners of the globe. It’s a ... in northwestern Bolivia where many have been sickened by ... Fairfield University’s School of Engineering has been working to ... (UAC), “the united college for the peasants.” A branch ...
(Date:10/31/2014)... 2014 Caustic soda is utilized in the ... At present, China takes lead in the global caustic soda ... a number of facilities in the USA, Germany, Brazil and ... soda market in terms of output and production capacities. , ... average by 3% per year in the years ahead. The ...
(Date:10/31/2014)... IL (PRWEB) October 30, 2014 ... Insight Product Development’s decades-long heritage in successful medical ... world context for what it takes to successfully ... space. As part of a two-hour on-site class, ... Kellogg school of business, McCormick School of Engineering, ...
(Date:10/31/2014)... MA (PRWEB) October 30, 2014 ... Latin America were hosted by Charm Sciences at ... During their week in the US, the participants ... residue control, hygiene management, and process verification, and ... facility. , This was the first visit to ...
Breaking Biology Technology:Fairfield University School of Engineering project reduces illness in rural community 2Fairfield University School of Engineering project reduces illness in rural community 3China to Dominate Caustic Soda Market Through 2018, Says Merchant Research & Consulting in Its New Study 2Insight Product Development Gives Northwestern University Students Foundation for Innovation Success 2Insight Product Development Gives Northwestern University Students Foundation for Innovation Success 3Charm Sciences Hosts Executives from Latin America for Dairy Safety Executive Seminar 2
Cached News: