HOME >> BIOLOGY >> NEWS
Bacterial response to oxidation studied as toxin barometer

Blacksburg, Va., March 26, 2007 Common bacteria with an overt reaction to toxins that cause oxidative stress show promise as a biosensor to predict public health threats.

At the 233rd American Chemical Society national meeting in Chicago March 25-29, researchers from Virginia Tech and the Edward Via Virginia College of Osteopathic Medicine (VCOM) will report their work on a bacteria biosensor prototype and correlations to brain tissue damage.

Many environmental toxins in water, such as pesticides, heavy metals, and PCBs, kill through oxidative stress mechanisms, said Bev Rzigalinski, a pharmacologist with VCOM. Oxidative stress is caused by unbalanced molecules called free radicals and other oxidation-promoting molecules that damage cells and genetic material by removing electrons.

Gram negative heterotrophic bacteria spit potassium in the presence of oxidative stress, said Nancy Love, a professor in civil and environmental engineering and an adjunct in biology at Virginia Tech.

More like sweat potassium, said Kaoru Ikuma of Nishinomiya, Japan, an environmental engineering graduate student at Virginia Tech.

However you describe the process for the non-scientist, the bacterias response of pushing potassium out of their cells in the presence of oxidative stress is called the glutathione-gated potassium efflux (GGKE) response. Typical bacterial you find anywhere will have this response, but these particular bacteria really spew potassium, said Love.

And Rzigalinski was pleased to hear it. Perhaps the GGKE response could be used to predict potential damage to animal and human cells. But bacteria are different from mammalian cells, said Rzigalinski, who is focused on neuroscience, particularly brain injury and aging, and nanotechnology (http://nanoneuro.vcom.vt.edu/).

We wanted to see if the same type of marker would work with human cells, particularly
'"/>

Contact: Susan Trulove
STrulove@vt.edu
540-231-5646
Virginia Tech
26-Mar-2007


Page: 1 2 3

Related biology news :

1. Better together: Bacterial endosymbionts are essential for the reproduction of a fungus
2. Bacterial walls come tumbling down
3. Bacterial switch gene regulates how oceans emit sulfur into atmosphere
4. Bacterial protein shows promise in treating intestinal parasites
5. The results are in: Bacterial parasite strives for balance in host infection
6. Bacterial protein mimics host to cripple defenses
7. Say what? Bacterial conversation stoppers
8. Bacterial cooperation as a target for anti-infectious therapy
9. New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids
10. Bacterial spread all down to chance: Some strains just the lucky ones
11. OHSU study: Bacterial switching mechanism key to survival

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/6/2019)... ... November 06, 2019 , ... In ... to provide information to patients about a poorly disclosed deficiency in stem cell ... knowing the dose of the treating stem cells. This problem affects all ...
(Date:11/5/2019)... ... November 05, 2019 , ... Dr. ... and restorative dentistry to Seattle, WA, including porcelain veneers , smile makeovers, ... from the University of Washington, Dr. Kopp is passionate about serving her Seattle ...
(Date:10/30/2019)... ... October 29, 2019 , ... LGC Maine Standards releases ... Order Numbers 701sa & 704sa. The kits, in a human-urine matrix, evaluate CA, ... Each VALIDATE® kit, liquid, ready-to-use, and prepared using the CLSI EP06-A “equal delta” ...
Breaking Biology News(10 mins):
(Date:11/9/2019)... ... November 08, 2019 , ... ... intelligence (AI)-powered technology for use in pathology research, today announced the results ... samples from patients enrolled in the phase 3 selonsertib studies (STELLAR). Strong ...
(Date:11/5/2019)... ... ... Ole, a German Shepherd, was demonstrating signs of osteoarthritis in April 2019. He was ... and his willingness to play were normal, it was clear that he was in pain. ... Animal Hospital and Referral Center in San Diego, California. Dr. Mullen is an ...
(Date:10/30/2019)... ... October 30, 2019 , ... Western University of Health ... and technology play in educating the next generation of health care providers. , ... presentations by WesternU administrators and representatives of companies working with the University on ...
(Date:10/22/2019)... , ... October 22, 2019 , ... nQ Medical, Inc. ... School’s 2019 Most Fundable Companies List which was announced at a showcase event yesterday ... million in annual revenue, strong business plans, and impressive near-term growth projections to be ...
Breaking Biology Technology:
Cached News: