HOME >> BIOLOGY >> NEWS
Being obese and a couch potato may have a biological basis in the brain

Bethesda, MD (August 14, 2006) -- Some brains may be wired to encourage fidgeting and other restless behaviors that consume calories and help control weight, according to new research published by The American Physiological Society.

The study found that the brains of rats bred to be lean are more sensitive to a chemical produced in the brain, orexin A, which stimulates appetite and spontaneous physical activity such as fidgeting and other unconscious movements. Compared to rats bred to be obese, the lean rats had a far greater expression of orexin receptors in the hypothalamus.

"The greater expression of orexin receptors suggests the lean rats' brains were more sensitive to the orexin the brain produces," said Catherine M. Kotz, the study's senior researcher. "The results point to a biological basis for being a couch potato."

This line of research suggests that frequent minor unconscious movements such as fidgeting and other behaviors associated with restlessness burn calories and help control weight, Kotz said. Further, it suggests a strategy to reduce weight gain and could lead to the development of a drug to stimulate minor activity.

The study "Elevated hypothalamic orexin signaling, sensitivity to orexin A and spontaneous physical activity in obesity resistant rats," appears in the online edition of the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology published by The American Physiological Society. The study was done by Jennifer A. Teske and Allen S. Levine of the University of Minnesota and the Minnesota Obesity Center, St. Paul; Michael Kuskowski, VA Medical Center, Minneapolis; James A. Levine, Mayo Clinic, Rochester, Minnesota; and Catherine M. Kotz, the VA Medical Center, University of Minnesota, and the Minnesota Obesity Center.

Study looks at obese versus lean rats

"Many people focus on diet, but it may be more feasible for some people to stand or move
'"/>

Contact: Christine Guilfoy
cguilfoy@the-aps.org
301-634-7253
American Physiological Society
14-Aug-2006


Page: 1 2 3

Related biology news :

1. Its safe for obese moms-to-be to lose weight during pregnancy, new SLU research finds
2. Difficult births in obese women due to uterus failure
3. Disease of older adults now seen in young, obese adults
4. Chemical compounds restore normal glucose levels and insulin action in obese mice
5. Stress imaging tests predict prognosis of heart disease in obese persons
6. Scientists find gene in obese mice that increases type 2 diabetes
7. Studies of obese children reveal body-weight control hormone
8. Muscle of obese programmed to amass fat, genetic study finds
9. Gene makes muscles in the obese store more fat
10. Fat buildup found in hearts of obese or diabetic heart failure patients
11. 15 generations of untrained jocks, couch potatoes show big physiological adaptations

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/18/2020)... ... July 17, 2020 , ... Commercial launch readiness is a critical ... discover a COVID cure or vaccine, the global economic downturn will only increase price ... not going away and capturing full value from every product launch is critical. However, ...
(Date:7/10/2020)... ... July 09, 2020 , ... Today CJ BIO announced ... will share insight on the “fifth taste” phenomenon that is revolutionizing ingredient mixes, nutritional ... Advantage will be live on Monday, July 13, 2020 at11:00 AM (CDT) during SHIFT20, ...
(Date:7/2/2020)... ... July 01, 2020 , ... AltruBio Inc. http://www.altrubio.com , ... biologic for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD), at European Hematology ... Martin of the Fred Hutchinson Cancer Research Center, this single-arm, open-label Phase 1 ...
Breaking Biology News(10 mins):
(Date:7/1/2020)... (PRWEB) , ... June 29, 2020 , ... ... access to competitively procured purchasing contracts to its membership, recently named BioFit ... TIPS members with the opportunity to purchase ergonomic seating, cafeteria tables, book trucks ...
(Date:6/28/2020)... NIGUEL, Calif. (PRWEB) , ... June 25, 2020 , ... ... announced the launch of Safe Space™ for businesses of all types to ensure cleanliness, ... 3D LiDAR. , A Safe Space™ enabled business will provide a health ...
(Date:6/28/2020)... ... June 25, 2020 , ... ... photodynamic therapy for treating cancer, today announced the company has entered a license ... The agreement provides Lumeda globally exclusive rights to Roswell Park intellectual property ...
(Date:6/23/2020)... ... June 23, 2020 , ... Kerafast Inc. , developers ... announced the availability of the Delta-G-VSV Pseudotyping System for coronavirus research applications. The ... of SARS-CoV-2 viral entry and COVID-19 vaccine effectiveness at just biosafety level 2 ...
Breaking Biology Technology:
Cached News: