HOME >> BIOLOGY >> NEWS
Big hips, big belly? It's in your genes, Joslin-led study shows

Boston -- Do you have big hips or a "beer" belly? Are you "apple-shaped" or "pear-shaped"? It makes a difference, since we know that abdominal obesity is linked to diabetes and many other metabolic conditions, i.e., the metabolic syndrome. What's new is that, according to a new study led by researchers at Joslin Diabetes Center in Boston, both obesity and body shape seem to be controlled by important genes that are part of the mechanisms regulating normal development.

"By looking at your genes, we can tell how fat you are and how your body fat will be distributed," said lead researcher C. Ronald Kahn, M.D., President of Joslin and the Mary K. Iacocca Professor of Medicine at Harvard Medical School. In lower animals, he added, it's long been known that genes play an important role in the body's development. "Genes tell the body where the head goes and where the tail goes, what goes on the front and what goes on the back. In insects, genes determine if the wings go on the front or back and whether they will be large or small. So it's not surprising that in humans, genes may determine how many fat cells we have and where they are located," he said.

Together with Joslin post-doctoral fellow Stephane Gesta, Ph.D., and colleagues at the University of Leipzig in Germany, the researchers for the first time used gene chips as a tool to understand what genes might control the development of fat inside the abdomen versus fat under the skin. The resulting study will be published online today, April 10, in the journal Proceedings of the National Academy of Sciences.

When it comes to obesity, the location of body fat can significantly impact one's risk for developing serious chronic diseases. Obesity, which is reaching worldwide epidemic proportions, is a major risk factor for type 2 diabetes, cardiovascular disease, cancer and other metabolic disorders. Doctors have long recognized that people who are "apple-shaped" -- with their fat concentrated in the
'"/>


10-Apr-2006


Page: 1 2 3

Related biology news :

1. Gene regulation, not just genes, is what sets humans apart
2. Hot flashes -- Studies explore the role of genes, obesity and alcohol
3. Parents genes, not parents arguing, may cause childrens conduct problems
4. Scientists identify 36 genes, 100 neuropeptides in honey bee brains
5. High tech detectives screen thousands of genes, proteins to solve puzzle of lung disease
6. Early family experience can reverse the effects of genes, UCLA psychologists report
7. Environment, not genes, key in family relationships
8. Research zeros in on bipolar disorder genes, link with thyroid condition
9. Joslin-led study uncovers role of appetite hormone MCH in insulin production
10. Joslin-led study reveals new findings on insulin signaling in the liver
11. Joslin-led study reveals findings on how insulin-producing beta cells grow and function

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/18/2020)... ... July 16, 2020 , ... A study ... the Invictus Medical Neoasis™ active noise control device to attenuate typical noises in ... Neoasis™ device attenuated the alarm sounds from patient monitors, ventilators and other bedside ...
(Date:7/10/2020)... ... 2020 , ... Today CJ BIO announced the first in a series of ... taste” phenomenon that is revolutionizing ingredient mixes, nutritional content and flavor profiles across a ... July 13, 2020 at11:00 AM (CDT) during SHIFT20, the virtual edition of the IFT ...
(Date:7/2/2020)... FREDERICK, Md. (PRWEB) , ... ... ... company, Molecular Biology Systems, B.V. (MBS) has announced a publication detailing the ... a one-step reverse transcription polymerase chain reaction (RT-PCR) in 16 minutes. The ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... July 29, 2020 , ... The SDX® Respiratory ... 16 countries, has reached its 20th anniversary of worldwide use. Introduced in the ... top universities including University of Pennsylvania, University of Michigan, University of Maryland, University ...
(Date:7/18/2020)... TORONTO (PRWEB) , ... July 16, 2020 , ... After ... begins. The completion of a great surgery is only the beginning of a successful ... the research community. , Join Brad Gien, Global Head of Surgery from Envigo ...
(Date:7/18/2020)... ... 2020 , ... dicentra , a leading Contract Research ... is pleased to announce that Charles Galea has joined its clinical trials division ... an accomplished and results-driven sales executive with over 10 years of expertise in ...
(Date:7/10/2020)... ... 2020 , ... In most research using the zebrafish model, ... in zebrafish embryos, maintaining optical transparency to facilitate microscopic imaging. Over the past ... the zebrafish model to investigate the causes of leukaemia and its relationship with ...
Breaking Biology Technology:
Cached News: