Biogen Idec acquires Brandeis spin-out

WALTHAM, MassSyntonix Pharmaceuticals, a spin-out company formed by Brandeis University, Brigham and Women's Hospital, and Children's Hospital Boston announced today that it was acquired by biotech giant Biogen Idec (NASDAQ: BIIB - News). Syntonix, a privately held biopharmaceutical company, was founded in 1997 based on breakthrough discoveries from the laboratories of Neil Simister, Ph.D. (Brandeis), Wayne Lencer, M.D. (Children's), and Richard S. Blumberg, M.D. (Brigham). Their research harnesses the human body's natural immunological pathways for novel methods of drug delivery.

"We founded Syntonix with the hope of translating our basic discoveries into improvements in healthcare. The company developed and expanded our technologies to the stage where they have preclinical candidates for treating hemophilia and infertility. Biogen Idec's acquisition is an excellent outcome because they have the expertise in manufacturing and development to bring these drugs to the clinic," said Neil Simister, a Brandeis biology professor and one of Syntonix' founders.

"Brandeis University has a very strong science faculty. This acquisition by Biogen Idec is evidence of the strength of Brandeis' technology. Brandeis has spun-out a number of companies; however, this is the first to be acquired by a large biotech. We are very pleased to have Biogen Idec as our new licensee and we look forward to their success with this technology," said Irene Abrams, the Director of the Office of Technology Licensing at Brandeis University.

Syntonix's lead product, FIX:Fc, is a proprietary long-acting factor IX product for the treatment of hemophilia B. It has the potential to reduce the frequency of intravenous injections required for disease management. Syntonix is expected to file an investigational new drug application with the Food and Drug Administration for FIX:Fc in 2007.

The transaction closed on Januray 31, 2007. In connection with the closing of th

Contact: Laura Gardner
Brandeis University

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